The effectiveness of cognitive behavioural therapy for depression in women with breast cancer: a systematic review and meta-analysis.

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Title: The effectiveness of cognitive behavioural therapy for depression in women with breast cancer: a systematic review and meta-analysis.
Authors: Wieland, Stephania (AUTHOR), Melton, Sarah (AUTHOR), Bastounis, Anastasios (AUTHOR), Carter, Tim (AUTHOR)
Source: Behavioural & Cognitive Psychotherapy. Jul2024, Vol. 52 Issue 4, p394-413. 20p.
Subjects: Depression in women, Behavior therapy, Cognitive therapy, Metastatic breast cancer, Cancer patients
Abstract: Background: Depression is a common co-morbidity in women with breast cancer. Previous systematic reviews investigating cognitive behavioural therapy (CBT) for depression in this population based their conclusions on findings from studies with varying and often limited specificity, quality and/or quantity of CBT within their interventions. Aim: To determine the effectiveness of a specific, well-evidenced CBT protocol for depression in women with breast cancer. Method: Online databases were systematically searched to identify randomised controlled trials (RCTs) testing CBT (aligned to Beck's protocol) as a treatment for depression in women with breast cancer. Screening, data extraction and risk of bias assessment were independently undertaken by two study authors. Both narrative synthesis and meta-analysis were used to analyse the data. The meta-analysis used a random effects model to compare CBT with non-active/active controls of depression using validated, self-report measures. Results: Six RCTs were included in the narrative synthesis, and five in the meta-analysis (n = 531 participants). Overall, CBT demonstrated an improvement in depression scores in the CBT condition versus active and non-active controls at post-intervention (SMD = –0.93 [95% CI –1.47, –0.40]). Narratively, five out of six RCTs reported statistically significant improvements in depression symptoms for CBT over control conditions for women with breast cancer. Conclusion: CBT aligned to Beck's protocol for depression appears effective for treating depression in women with breast cancer. However, further research is needed for women with stage IV breast cancer. The clinical recommendation is that therapists utilise Beck's CBT protocol for depression, whilst considering the complex presentation and adapt their practice accordingly. [ABSTRACT FROM AUTHOR]
Copyright of Behavioural & Cognitive Psychotherapy is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The effectiveness of cognitive behavioural therapy for depression in women with breast cancer: a systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AR" term="%22Wieland%2C+Stephania%22">Wieland, Stephania</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Melton%2C+Sarah%22">Melton, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bastounis%2C+Anastasios%22">Bastounis, Anastasios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Carter%2C+Tim%22">Carter, Tim</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Behavioural+%26+Cognitive+Psychotherapy%22">Behavioural & Cognitive Psychotherapy</searchLink>. Jul2024, Vol. 52 Issue 4, p394-413. 20p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Depression+in+women%22">Depression in women</searchLink><br /><searchLink fieldCode="DE" term="%22Behavior+therapy%22">Behavior therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Metastatic+breast+cancer%22">Metastatic breast cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+patients%22">Cancer patients</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Depression is a common co-morbidity in women with breast cancer. Previous systematic reviews investigating cognitive behavioural therapy (CBT) for depression in this population based their conclusions on findings from studies with varying and often limited specificity, quality and/or quantity of CBT within their interventions. Aim: To determine the effectiveness of a specific, well-evidenced CBT protocol for depression in women with breast cancer. Method: Online databases were systematically searched to identify randomised controlled trials (RCTs) testing CBT (aligned to Beck's protocol) as a treatment for depression in women with breast cancer. Screening, data extraction and risk of bias assessment were independently undertaken by two study authors. Both narrative synthesis and meta-analysis were used to analyse the data. The meta-analysis used a random effects model to compare CBT with non-active/active controls of depression using validated, self-report measures. Results: Six RCTs were included in the narrative synthesis, and five in the meta-analysis (n = 531 participants). Overall, CBT demonstrated an improvement in depression scores in the CBT condition versus active and non-active controls at post-intervention (SMD = –0.93 [95% CI –1.47, –0.40]). Narratively, five out of six RCTs reported statistically significant improvements in depression symptoms for CBT over control conditions for women with breast cancer. Conclusion: CBT aligned to Beck's protocol for depression appears effective for treating depression in women with breast cancer. However, further research is needed for women with stage IV breast cancer. The clinical recommendation is that therapists utilise Beck's CBT protocol for depression, whilst considering the complex presentation and adapt their practice accordingly. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Behavioural & Cognitive Psychotherapy is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1017/S1352465824000092
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      – Code: eng
        Text: English
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        Type: general
      – SubjectFull: Behavior therapy
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      – SubjectFull: Cognitive therapy
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      – SubjectFull: Metastatic breast cancer
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      – SubjectFull: Cancer patients
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              M: 07
              Text: Jul2024
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              Y: 2024
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