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Preoperative antiplatelet therapy may be a risk factor for postoperative ischemic complications in intracranial hemorrhage patients.

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Title: Preoperative antiplatelet therapy may be a risk factor for postoperative ischemic complications in intracranial hemorrhage patients.
Authors: Yang, Junhua (AUTHOR), Wang, Kaiwen (AUTHOR), Han, Chao (AUTHOR), Liu, Qingyuan (AUTHOR), Zhang, Shuo (AUTHOR), Wu, Jun (AUTHOR), Jiang, Pengjun (AUTHOR), Yang, Shuzhe (AUTHOR), Guo, Rui (AUTHOR), Mo, Shaohua (AUTHOR), Yang, Yi (AUTHOR), Zhang, Jiaming (AUTHOR), Liu, Yang (AUTHOR), Cao, Yong (AUTHOR), Wang, Shuo (AUTHOR)
Source: International Journal of Neuroscience. Aug2024, Vol. 134 Issue 8, p899-905. 7p.
Subjects: Preoperative risk factors, Disease risk factors, Intracranial hematoma, Intracranial hemorrhage, Survival analysis (Biometry)
Abstract: Spontaneous intracranial hemorrhage (ICH) patients are still at risk of postoperative ischemic complications (PICs) after surgery. In addition, the proportion of patients receiving antiplatelet therapy (APT) in ICH patients increased significantly with age. This study aims to evaluate the impact of preoperative antiplatelet therapy on PICs in ICH patients. This is a cohort study that retrospectively analyzed the data of ICH patients who underwent surgical treatment. PICs rate was compared between patients with preoperative ATP and those without preoperative ATP. Univariate and multivariate analyses were conducted to evaluate the impact of preoperative APT on PICs. In addition, Kaplan-Meier method was used for survival analysis and the impact of PICs on patients' postoperative outcomes was evaluated. A total of 216 patients were included in this study. There were 47 patients (21.76%) with preoperative APT; 169 patients (78.24%) without preoperative APT. The incidence of PICs in the APT group was significantly higher when compared with that in the nAPT group (36.17% vs. 20.71%, p = 0.028＜0.05). Furthermore, significant differences were both observed in multivariate analysis (p = 0.035＜0.05) and survival analysis (log rank χ2 = 5.415, p = 0.020＜0.05). However, there was no significant difference between the outcomes of patients suffering from PICs and that of patients not suffering from PICs (p = 0.377 > 0.05). In conclusion, preoperative APT may be a risk factor for PICs in ICH patients undergoing surgical treatment significantly. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
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  Data: Preoperative antiplatelet therapy may be a risk factor for postoperative ischemic complications in intracranial hemorrhage patients.
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  Data: <searchLink fieldCode="AR" term="%22Yang%2C+Junhua%22">Yang, Junhua</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Kaiwen%22">Wang, Kaiwen</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Han%2C+Chao%22">Han, Chao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Qingyuan%22">Liu, Qingyuan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Shuo%22">Zhang, Shuo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Jun%22">Wu, Jun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jiang%2C+Pengjun%22">Jiang, Pengjun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Shuzhe%22">Yang, Shuzhe</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guo%2C+Rui%22">Guo, Rui</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mo%2C+Shaohua%22">Mo, Shaohua</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Yi%22">Yang, Yi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Jiaming%22">Zhang, Jiaming</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Yang%22">Liu, Yang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cao%2C+Yong%22">Cao, Yong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Shuo%22">Wang, Shuo</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Neuroscience%22">International Journal of Neuroscience</searchLink>. Aug2024, Vol. 134 Issue 8, p899-905. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Preoperative+risk+factors%22">Preoperative risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Intracranial+hematoma%22">Intracranial hematoma</searchLink><br /><searchLink fieldCode="DE" term="%22Intracranial+hemorrhage%22">Intracranial hemorrhage</searchLink><br /><searchLink fieldCode="DE" term="%22Survival+analysis+%28Biometry%29%22">Survival analysis (Biometry)</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Spontaneous intracranial hemorrhage (ICH) patients are still at risk of postoperative ischemic complications (PICs) after surgery. In addition, the proportion of patients receiving antiplatelet therapy (APT) in ICH patients increased significantly with age. This study aims to evaluate the impact of preoperative antiplatelet therapy on PICs in ICH patients. This is a cohort study that retrospectively analyzed the data of ICH patients who underwent surgical treatment. PICs rate was compared between patients with preoperative ATP and those without preoperative ATP. Univariate and multivariate analyses were conducted to evaluate the impact of preoperative APT on PICs. In addition, Kaplan-Meier method was used for survival analysis and the impact of PICs on patients' postoperative outcomes was evaluated. A total of 216 patients were included in this study. There were 47 patients (21.76%) with preoperative APT; 169 patients (78.24%) without preoperative APT. The incidence of PICs in the APT group was significantly higher when compared with that in the nAPT group (36.17% vs. 20.71%, p = 0.028＜0.05). Furthermore, significant differences were both observed in multivariate analysis (p = 0.035＜0.05) and survival analysis (log rank χ2 = 5.415, p = 0.020＜0.05). However, there was no significant difference between the outcomes of patients suffering from PICs and that of patients not suffering from PICs (p = 0.377 > 0.05). In conclusion, preoperative APT may be a risk factor for PICs in ICH patients undergoing surgical treatment significantly. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/00207454.2022.2157724
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      – Code: eng
        Text: English
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        PageCount: 7
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    Subjects:
      – SubjectFull: Preoperative risk factors
        Type: general
      – SubjectFull: Disease risk factors
        Type: general
      – SubjectFull: Intracranial hematoma
        Type: general
      – SubjectFull: Intracranial hemorrhage
        Type: general
      – SubjectFull: Survival analysis (Biometry)
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    Titles:
      – TitleFull: Preoperative antiplatelet therapy may be a risk factor for postoperative ischemic complications in intracranial hemorrhage patients.
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              Text: Aug2024
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