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Change of function and brain activity in patients of right spastic arm paralysis combined with aphasia after contralateral cervical seventh nerve transfer surgery.

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Title: Change of function and brain activity in patients of right spastic arm paralysis combined with aphasia after contralateral cervical seventh nerve transfer surgery.
Authors: Feng, Juntao (AUTHOR), Lv, Minzhi (AUTHOR), Ma, Xingyi (AUTHOR), Li, Tie (AUTHOR), Xu, Miaomiao (AUTHOR), Yang, Jingrui (AUTHOR), Su, Fan (AUTHOR), Hu, Ruiping (AUTHOR), Li, Jie (AUTHOR), Qiu, Yanqun (AUTHOR), Liu, Ying (AUTHOR), Shen, Yundong (AUTHOR), Xu, Wendong (AUTHOR)
Source: European Journal of Neuroscience. Aug2024, Vol. 60 Issue 3, p4254-4264. 11p.
Subjects: Spastic paralysis, Prefrontal cortex, Cervical plexus, Functional magnetic resonance imaging, Aphasic persons
Abstract: Left hemisphere injury can cause right spastic arm paralysis and aphasia, and recovery of both motor and language functions shares similar compensatory mechanisms and processes. Contralateral cervical seventh cross transfer (CC7) surgery can provide motor recovery for spastic arm paralysis by triggering interhemispheric plasticity, and self‐reports from patients indicate spontaneous improvement in language function but still need to be verified. To explore the improvements in motor and language function after CC7 surgery, we performed this prospective observational cohort study. The Upper Extremity part of Fugl‐Meyer scale (UEFM) and Modified Ashworth Scale were used to evaluate motor function, and Aphasia Quotient calculated by Mandarin version of the Western Aphasia Battery (WAB‐AQ, larger score indicates better language function) was assessed for language function. In 20 patients included, the average scores of UEFM increased by.40 and 3.70 points from baseline to 1‐week and 6‐month post‐surgery, respectively. The spasticity of the elbow and fingers decreased significantly at 1‐week post‐surgery, although partially recurred at 6‐month follow‐up. The average scores of WAB‐AQ were increased by 9.14 and 10.69 points at 1‐week and 6‐month post‐surgery (P <.001 for both), respectively. Post‐surgical fMRI scans revealed increased activity in the bilateral hemispheres related to language centrals, including the right precentral cortex and right gyrus rectus. These findings suggest that CC7 surgery not only enhances motor function but may also improve the aphasia quotient in patients with right arm paralysis and aphasia due to left hemisphere injuries. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Change of function and brain activity in patients of right spastic arm paralysis combined with aphasia after contralateral cervical seventh nerve transfer surgery.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Feng%2C+Juntao%22&quot;&gt;Feng, Juntao&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lv%2C+Minzhi%22&quot;&gt;Lv, Minzhi&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ma%2C+Xingyi%22&quot;&gt;Ma, Xingyi&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Li%2C+Tie%22&quot;&gt;Li, Tie&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Xu%2C+Miaomiao%22&quot;&gt;Xu, Miaomiao&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yang%2C+Jingrui%22&quot;&gt;Yang, Jingrui&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Su%2C+Fan%22&quot;&gt;Su, Fan&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hu%2C+Ruiping%22&quot;&gt;Hu, Ruiping&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Li%2C+Jie%22&quot;&gt;Li, Jie&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Qiu%2C+Yanqun%22&quot;&gt;Qiu, Yanqun&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Liu%2C+Ying%22&quot;&gt;Liu, Ying&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Shen%2C+Yundong%22&quot;&gt;Shen, Yundong&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Xu%2C+Wendong%22&quot;&gt;Xu, Wendong&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neuroscience%22&quot;&gt;European Journal of Neuroscience&lt;/searchLink&gt;. Aug2024, Vol. 60 Issue 3, p4254-4264. 11p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Spastic+paralysis%22&quot;&gt;Spastic paralysis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prefrontal+cortex%22&quot;&gt;Prefrontal cortex&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cervical+plexus%22&quot;&gt;Cervical plexus&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Functional+magnetic+resonance+imaging%22&quot;&gt;Functional magnetic resonance imaging&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Aphasic+persons%22&quot;&gt;Aphasic persons&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Left hemisphere injury can cause right spastic arm paralysis and aphasia, and recovery of both motor and language functions shares similar compensatory mechanisms and processes. Contralateral cervical seventh cross transfer (CC7) surgery can provide motor recovery for spastic arm paralysis by triggering interhemispheric plasticity, and self‐reports from patients indicate spontaneous improvement in language function but still need to be verified. To explore the improvements in motor and language function after CC7 surgery, we performed this prospective observational cohort study. The Upper Extremity part of Fugl‐Meyer scale (UEFM) and Modified Ashworth Scale were used to evaluate motor function, and Aphasia Quotient calculated by Mandarin version of the Western Aphasia Battery (WAB‐AQ, larger score indicates better language function) was assessed for language function. In 20 patients included, the average scores of UEFM increased by.40 and 3.70 points from baseline to 1‐week and 6‐month post‐surgery, respectively. The spasticity of the elbow and fingers decreased significantly at 1‐week post‐surgery, although partially recurred at 6‐month follow‐up. The average scores of WAB‐AQ were increased by 9.14 and 10.69 points at 1‐week and 6‐month post‐surgery (P &lt;.001 for both), respectively. Post‐surgical fMRI scans revealed increased activity in the bilateral hemispheres related to language centrals, including the right precentral cortex and right gyrus rectus. These findings suggest that CC7 surgery not only enhances motor function but may also improve the aphasia quotient in patients with right arm paralysis and aphasia due to left hemisphere injuries. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=178854268
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        Value: 10.1111/ejn.16436
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        Text: English
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        PageCount: 11
        StartPage: 4254
    Subjects:
      – SubjectFull: Spastic paralysis
        Type: general
      – SubjectFull: Prefrontal cortex
        Type: general
      – SubjectFull: Cervical plexus
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      – SubjectFull: Functional magnetic resonance imaging
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      – SubjectFull: Aphasic persons
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      – TitleFull: Change of function and brain activity in patients of right spastic arm paralysis combined with aphasia after contralateral cervical seventh nerve transfer surgery.
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              M: 08
              Text: Aug2024
              Type: published
              Y: 2024
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