Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia.

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Title: Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia.
Authors: Bucci, Paola (AUTHOR), Mucci, Armida (AUTHOR), Giordano, Giulia M. (AUTHOR), Caporusso, Edoardo (AUTHOR), Giuliani, Luigi (AUTHOR), Gibertoni, Dino (AUTHOR), Rossi, Alessandro (AUTHOR), Rocca, Paola (AUTHOR), Bertolino, Alessandro (AUTHOR), Galderisi, Silvana (AUTHOR), Piegari, Giuseppe (AUTHOR), Merlotti, Eleonora (AUTHOR), Brando, Francesco (AUTHOR), Papalino, Marco (AUTHOR), Calia, Vitalba (AUTHOR), Romano, Raffaella (AUTHOR), Barlati, Stefano (AUTHOR), Deste, Giacomo (AUTHOR), Valsecchi, Paolo (AUTHOR), Pinna, Federica (AUTHOR)
Source: European Archives of Psychiatry & Clinical Neuroscience. Sep2024, Vol. 274 Issue 6, p1343-1354. 12p.
Subjects: Cognitive interviewing, Multiple regression analysis, Cognition disorders, Medical history taking, Mental depression
Abstract: The Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients' insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet's agreement coefficient. Predictors of insight in cognitive deficits were explored by stepwise multiple regression analyses. Patients reported lower severity of cognitive impairment vs. informants. A substantial to almost perfect agreement was observed between patients' and informants' ratings. Lower insight in cognitive deficits was associated to greater severity of neurocognitive impairment and positive symptoms, lower severity of depressive symptoms, and older age. Worse real-life functioning was associated to lower insight in cognitive deficit, worse neurocognitive performance, and worse functional capacity. Our findings indicate that the CAI is a valid co-primary measure with the interview to patients providing a reliable assessment of their cognitive deficits. In the absence of informants with good knowledge of the subject, the interview to the patient may represent a valid alternative. [ABSTRACT FROM AUTHOR]
Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia.
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  Data: <searchLink fieldCode="AR" term="%22Bucci%2C+Paola%22">Bucci, Paola</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mucci%2C+Armida%22">Mucci, Armida</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Giordano%2C+Giulia+M%2E%22">Giordano, Giulia M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Caporusso%2C+Edoardo%22">Caporusso, Edoardo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Giuliani%2C+Luigi%22">Giuliani, Luigi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gibertoni%2C+Dino%22">Gibertoni, Dino</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rossi%2C+Alessandro%22">Rossi, Alessandro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rocca%2C+Paola%22">Rocca, Paola</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bertolino%2C+Alessandro%22">Bertolino, Alessandro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Galderisi%2C+Silvana%22">Galderisi, Silvana</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Piegari%2C+Giuseppe%22">Piegari, Giuseppe</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Merlotti%2C+Eleonora%22">Merlotti, Eleonora</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Brando%2C+Francesco%22">Brando, Francesco</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Papalino%2C+Marco%22">Papalino, Marco</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Calia%2C+Vitalba%22">Calia, Vitalba</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Romano%2C+Raffaella%22">Romano, Raffaella</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Barlati%2C+Stefano%22">Barlati, Stefano</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Deste%2C+Giacomo%22">Deste, Giacomo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Valsecchi%2C+Paolo%22">Valsecchi, Paolo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pinna%2C+Federica%22">Pinna, Federica</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. Sep2024, Vol. 274 Issue 6, p1343-1354. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Cognitive+interviewing%22">Cognitive interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+regression+analysis%22">Multiple regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+history+taking%22">Medical history taking</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink>
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  Data: The Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients' insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet's agreement coefficient. Predictors of insight in cognitive deficits were explored by stepwise multiple regression analyses. Patients reported lower severity of cognitive impairment vs. informants. A substantial to almost perfect agreement was observed between patients' and informants' ratings. Lower insight in cognitive deficits was associated to greater severity of neurocognitive impairment and positive symptoms, lower severity of depressive symptoms, and older age. Worse real-life functioning was associated to lower insight in cognitive deficit, worse neurocognitive performance, and worse functional capacity. Our findings indicate that the CAI is a valid co-primary measure with the interview to patients providing a reliable assessment of their cognitive deficits. In the absence of informants with good knowledge of the subject, the interview to the patient may represent a valid alternative. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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