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A 3‐year retrospective review of hospital admissions involving opioid toxicity in South Australia.

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Title: A 3‐year retrospective review of hospital admissions involving opioid toxicity in South Australia.
Authors: Sarantou, Maria (AUTHOR), Burke, Anne L. J. (AUTHOR), Semple, Tim (AUTHOR), Johnson, Jacinta L. (AUTHOR)
Source: Drug & Alcohol Review. Sep2024, Vol. 43 Issue 6, p1607-1612. 6p.
Subjects: Cost estimates, Public hospitals, Nosology, Hospital admission & discharge, Artificial respiration
Abstract: Introduction: This article aims to characterise hospital admissions involving opioid toxicity across South Australia to guide future implementation and evaluation of risk mitigation strategies. Methods: International Classification of Diseases, 10th Edition codes (T40.0–T40.4) were used to identify admissions involving pre‐hospital opioid toxicity in public hospitals across South Australia from 1 June 2017 to 30 August 2020. Demographic and episode of care data were extracted and summarised using descriptive statistics. Admission cost estimates were calculated using Independent Hospital Pricing Authority data. Results: A total of 2046 cases met the criteria for inclusion; over half (56%) were female and median age on admission was 44 years (interquartile range 27 years). Where opioid toxicity was the primary diagnosis, 70% of admissions did not specify the responsible opioid and 23% were related to heroin use. One‐fifth of admissions occurred outside of metropolitan Adelaide. Individuals living in an area of relative socio‐economic disadvantage were over‐represented. Over half of admissions required a stay >24 h; 19% were admitted for ≥5 days, 22% required intensive care and ~10% required mechanical ventilation. The total estimated cost of admissions involving opioid toxicity in South Australia over the 3‐year period was $18,230,546.50, equating to $5.6 million per annum. Discussions and Conclusions: These findings highlight the significant personal, fiscal, and systemic impacts of opioid toxicity‐related hospital admissions in South Australia and provide a baseline to evaluate the effectiveness of initiatives to reduce opioid‐related harm, including real‐time prescription monitoring and take‐home naloxone supply. [ABSTRACT FROM AUTHOR]
Copyright of Drug & Alcohol Review is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: A 3‐year retrospective review of hospital admissions involving opioid toxicity in South Australia.
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  Data: <searchLink fieldCode="AR" term="%22Sarantou%2C+Maria%22">Sarantou, Maria</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burke%2C+Anne+L%2E+J%2E%22">Burke, Anne L. J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Semple%2C+Tim%22">Semple, Tim</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Johnson%2C+Jacinta+L%2E%22">Johnson, Jacinta L.</searchLink> (AUTHOR)
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  Data: Introduction: This article aims to characterise hospital admissions involving opioid toxicity across South Australia to guide future implementation and evaluation of risk mitigation strategies. Methods: International Classification of Diseases, 10th Edition codes (T40.0–T40.4) were used to identify admissions involving pre‐hospital opioid toxicity in public hospitals across South Australia from 1 June 2017 to 30 August 2020. Demographic and episode of care data were extracted and summarised using descriptive statistics. Admission cost estimates were calculated using Independent Hospital Pricing Authority data. Results: A total of 2046 cases met the criteria for inclusion; over half (56%) were female and median age on admission was 44 years (interquartile range 27 years). Where opioid toxicity was the primary diagnosis, 70% of admissions did not specify the responsible opioid and 23% were related to heroin use. One‐fifth of admissions occurred outside of metropolitan Adelaide. Individuals living in an area of relative socio‐economic disadvantage were over‐represented. Over half of admissions required a stay >24 h; 19% were admitted for ≥5 days, 22% required intensive care and ~10% required mechanical ventilation. The total estimated cost of admissions involving opioid toxicity in South Australia over the 3‐year period was $18,230,546.50, equating to $5.6 million per annum. Discussions and Conclusions: These findings highlight the significant personal, fiscal, and systemic impacts of opioid toxicity‐related hospital admissions in South Australia and provide a baseline to evaluate the effectiveness of initiatives to reduce opioid‐related harm, including real‐time prescription monitoring and take‐home naloxone supply. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Drug & Alcohol Review is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Sep2024
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