View in EDS HTML Full Text PDF Full Text

Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis.

Saved in:
Bibliographic Details
Title: Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis.
Authors: Di Gennaro, Giancarlo (AUTHOR), Romigi, Andrea (AUTHOR), Quarato, Pier Paolo (AUTHOR), Mascia, Addolorata (AUTHOR), D'Aniello, Alfredo (AUTHOR), Panzini, Chiara (AUTHOR), Casciato, Sara (AUTHOR), Grammaldo, Liliana (AUTHOR), Centonze, Diego (AUTHOR), Esposito, Vincenzo (AUTHOR)
Source: Neurological Sciences. Oct2024, Vol. 45 Issue 10, p5003-5009. 7p.
Subjects: Temporal lobe epilepsy, Hippocampal sclerosis, Epilepsy surgery, Prognosis, Age of onset, Temporal lobectomy
Abstract: Background: Temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) is a surgically treatable epileptic syndrome. While the core of pre-surgical evaluations rely on video-EEG, recent studies question the necessity of recorded seizures denying a possible role of ictal EEG in surgical decision. This study aims to retrospectively assess the prognostic value of EEG ictal patterns in TLE-HS, in order to identify which patients need further investigations before offering surgery. Methods: We included TLE-HS patients who underwent surgery with at least one captured seizure during non-invasive pre-surgical video-EEG recordings. They were classified in "mesial" and "lateral/mixed", according to the ictal EEG patterns, defined by the frequency of the discharge (mesial ≥ 5 Hz, lateral < 5 Hz). Seizure outcome was assessed by Engel's Class. Statistical analyses were performed to evaluate associations between EEG patterns and post-surgical outcomes. Results: Sixty-nine exhibited a mesial pattern, forty- two displayed lateral/mixed patterns. Mesial pattern group had a significantly higher rate of postsurgical seizure freedom (82.7% vs. 28.6%). Gender, age of onset, age at surgery, duration of epilepsy, seizure frequency, and lateralization did not influence the outcome. Mesial pattern significantly correlated with favorable outcomes (p < 0.001), suggesting its potential predictive value. Conclusion: This retrospective study proposes ictal EEG patterns as possible predictors of postoperative prognosis in TLE-HS. A mesial pattern correlates with better outcomes, indicating a potentially more circumscribed epileptogenic zone. Patients with lateral/mixed patterns may benefit from additional investigations to delineate the epileptogenic zone. Further studies are warranted to validate and extend these findings. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 179814933
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Di+Gennaro%2C+Giancarlo%22&quot;&gt;Di Gennaro, Giancarlo&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Romigi%2C+Andrea%22&quot;&gt;Romigi, Andrea&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Quarato%2C+Pier+Paolo%22&quot;&gt;Quarato, Pier Paolo&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mascia%2C+Addolorata%22&quot;&gt;Mascia, Addolorata&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22D&#39;Aniello%2C+Alfredo%22&quot;&gt;D&#39;Aniello, Alfredo&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Panzini%2C+Chiara%22&quot;&gt;Panzini, Chiara&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Casciato%2C+Sara%22&quot;&gt;Casciato, Sara&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Grammaldo%2C+Liliana%22&quot;&gt;Grammaldo, Liliana&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Centonze%2C+Diego%22&quot;&gt;Centonze, Diego&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Esposito%2C+Vincenzo%22&quot;&gt;Esposito, Vincenzo&lt;/searchLink&gt; (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Neurological+Sciences%22&quot;&gt;Neurological Sciences&lt;/searchLink&gt;. Oct2024, Vol. 45 Issue 10, p5003-5009. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Temporal+lobe+epilepsy%22&quot;&gt;Temporal lobe epilepsy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hippocampal+sclerosis%22&quot;&gt;Hippocampal sclerosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Epilepsy+surgery%22&quot;&gt;Epilepsy surgery&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prognosis%22&quot;&gt;Prognosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Age+of+onset%22&quot;&gt;Age of onset&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Temporal+lobectomy%22&quot;&gt;Temporal lobectomy&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) is a surgically treatable epileptic syndrome. While the core of pre-surgical evaluations rely on video-EEG, recent studies question the necessity of recorded seizures denying a possible role of ictal EEG in surgical decision. This study aims to retrospectively assess the prognostic value of EEG ictal patterns in TLE-HS, in order to identify which patients need further investigations before offering surgery. Methods: We included TLE-HS patients who underwent surgery with at least one captured seizure during non-invasive pre-surgical video-EEG recordings. They were classified in &quot;mesial&quot; and &quot;lateral/mixed&quot;, according to the ictal EEG patterns, defined by the frequency of the discharge (mesial ≥ 5 Hz, lateral &lt; 5 Hz). Seizure outcome was assessed by Engel&#39;s Class. Statistical analyses were performed to evaluate associations between EEG patterns and post-surgical outcomes. Results: Sixty-nine exhibited a mesial pattern, forty- two displayed lateral/mixed patterns. Mesial pattern group had a significantly higher rate of postsurgical seizure freedom (82.7% vs. 28.6%). Gender, age of onset, age at surgery, duration of epilepsy, seizure frequency, and lateralization did not influence the outcome. Mesial pattern significantly correlated with favorable outcomes (p &lt; 0.001), suggesting its potential predictive value. Conclusion: This retrospective study proposes ictal EEG patterns as possible predictors of postoperative prognosis in TLE-HS. A mesial pattern correlates with better outcomes, indicating a potentially more circumscribed epileptogenic zone. Patients with lateral/mixed patterns may benefit from additional investigations to delineate the epileptogenic zone. Further studies are warranted to validate and extend these findings. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=179814933
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10072-024-07564-y
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 5003
    Subjects:
      – SubjectFull: Temporal lobe epilepsy
        Type: general
      – SubjectFull: Hippocampal sclerosis
        Type: general
      – SubjectFull: Epilepsy surgery
        Type: general
      – SubjectFull: Prognosis
        Type: general
      – SubjectFull: Age of onset
        Type: general
      – SubjectFull: Temporal lobectomy
        Type: general
    Titles:
      – TitleFull: Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Di Gennaro, Giancarlo
      – PersonEntity:
          Name:
            NameFull: Romigi, Andrea
      – PersonEntity:
          Name:
            NameFull: Quarato, Pier Paolo
      – PersonEntity:
          Name:
            NameFull: Mascia, Addolorata
      – PersonEntity:
          Name:
            NameFull: D'Aniello, Alfredo
      – PersonEntity:
          Name:
            NameFull: Panzini, Chiara
      – PersonEntity:
          Name:
            NameFull: Casciato, Sara
      – PersonEntity:
          Name:
            NameFull: Grammaldo, Liliana
      – PersonEntity:
          Name:
            NameFull: Centonze, Diego
      – PersonEntity:
          Name:
            NameFull: Esposito, Vincenzo
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 15901874
          Numbering:
            – Type: volume
              Value: 45
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Neurological Sciences
              Type: main
ResultId 1