The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature.
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| Title: | The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature. |
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| Authors: | Biassoni, Erica (AUTHOR), Bellucci, Margherita (AUTHOR), Micalizzi, Elisa (AUTHOR), Miggino, Marco (AUTHOR), Andorno, Enzo (AUTHOR), Porcile, Elisa (AUTHOR), Resaz, Martina (AUTHOR), Roccatagliata, Luca (AUTHOR), Castellan, Lucio (AUTHOR), Villani, Flavio (AUTHOR), Ferrari, Alessandra (AUTHOR) |
| Source: | Neurological Sciences. Oct2024, Vol. 45 Issue 10, p5053-5062. 10p. |
| Subjects: | Alcoholism, Prognosis, Epilepsy, Status epilepticus, Seizures (Medicine), Hyperperfusion |
| Abstract: | Epileptic seizures are frequently associated with liver dysfunction and alcoholism. Subacute encephalopathy with seizures in chronic alcoholics (SESA) is an underrecognized condition with peculiar clinical, EEG and neuroradiological features. We report the case of a 58-year-old man with previous alcohol use disorder (AUD) and acute-on chronic liver failure on alcohol-related cirrhosis, referred for urgent Orthotopic Liver Transplantation evaluation. The patient presented with delirium, aphasia and progressive deterioration of consciousness leading to intensive care unit admission. EEG showed slow activity with superimposed lateralized periodic discharges (LPDs) over the left temporo-occipital regions and ictal discharges with focal motor phenomena, consistent with focal status epilepticus. Antiseizure treatment with lacosamide and levetiracetam was administered with progressive improvement of consciousness. Brain MRI disclosed T2/FLAIR areas of hyperintensity in the left pulvinar and T2/FLAIR hyperintensity with corresponding DWI hyperintensity in the left hippocampal cortex, suggestive of post/peri-ictal excitotoxic changes with anatomical correspondence to focal LPDs distribution. SWI demonstrated decreased prominence of cortical veins in the left temporo-occipital region consistent with increased venous blood oxygenation in compensatory hyperperfusion. In conclusion, SESA should be suspected in the differential diagnosis of patients with AUD presenting with focal neurological deficits, seizures and focal EEG abnormalities. In this context, EEG and brain MRI represent useful tools with both diagnostic and prognostic value. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 179814953 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Biassoni%2C+Erica%22">Biassoni, Erica</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bellucci%2C+Margherita%22">Bellucci, Margherita</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Micalizzi%2C+Elisa%22">Micalizzi, Elisa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miggino%2C+Marco%22">Miggino, Marco</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Andorno%2C+Enzo%22">Andorno, Enzo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Porcile%2C+Elisa%22">Porcile, Elisa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Resaz%2C+Martina%22">Resaz, Martina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Roccatagliata%2C+Luca%22">Roccatagliata, Luca</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Castellan%2C+Lucio%22">Castellan, Lucio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Villani%2C+Flavio%22">Villani, Flavio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ferrari%2C+Alessandra%22">Ferrari, Alessandra</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Oct2024, Vol. 45 Issue 10, p5053-5062. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Alcoholism%22">Alcoholism</searchLink><br /><searchLink fieldCode="DE" term="%22Prognosis%22">Prognosis</searchLink><br /><searchLink fieldCode="DE" term="%22Epilepsy%22">Epilepsy</searchLink><br /><searchLink fieldCode="DE" term="%22Status+epilepticus%22">Status epilepticus</searchLink><br /><searchLink fieldCode="DE" term="%22Seizures+%28Medicine%29%22">Seizures (Medicine)</searchLink><br /><searchLink fieldCode="DE" term="%22Hyperperfusion%22">Hyperperfusion</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Epileptic seizures are frequently associated with liver dysfunction and alcoholism. Subacute encephalopathy with seizures in chronic alcoholics (SESA) is an underrecognized condition with peculiar clinical, EEG and neuroradiological features. We report the case of a 58-year-old man with previous alcohol use disorder (AUD) and acute-on chronic liver failure on alcohol-related cirrhosis, referred for urgent Orthotopic Liver Transplantation evaluation. The patient presented with delirium, aphasia and progressive deterioration of consciousness leading to intensive care unit admission. EEG showed slow activity with superimposed lateralized periodic discharges (LPDs) over the left temporo-occipital regions and ictal discharges with focal motor phenomena, consistent with focal status epilepticus. Antiseizure treatment with lacosamide and levetiracetam was administered with progressive improvement of consciousness. Brain MRI disclosed T2/FLAIR areas of hyperintensity in the left pulvinar and T2/FLAIR hyperintensity with corresponding DWI hyperintensity in the left hippocampal cortex, suggestive of post/peri-ictal excitotoxic changes with anatomical correspondence to focal LPDs distribution. SWI demonstrated decreased prominence of cortical veins in the left temporo-occipital region consistent with increased venous blood oxygenation in compensatory hyperperfusion. In conclusion, SESA should be suspected in the differential diagnosis of patients with AUD presenting with focal neurological deficits, seizures and focal EEG abnormalities. In this context, EEG and brain MRI represent useful tools with both diagnostic and prognostic value. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10072-024-07609-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 5053 Subjects: – SubjectFull: Alcoholism Type: general – SubjectFull: Prognosis Type: general – SubjectFull: Epilepsy Type: general – SubjectFull: Status epilepticus Type: general – SubjectFull: Seizures (Medicine) Type: general – SubjectFull: Hyperperfusion Type: general Titles: – TitleFull: The role of EEG and neuroimaging in the diagnosis of non-convulsive status epilepticus in Subacute Encephalopathy with Seizures in Alcoholics (SESA syndrome): a case report and overview of the literature. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Biassoni, Erica – PersonEntity: Name: NameFull: Bellucci, Margherita – PersonEntity: Name: NameFull: Micalizzi, Elisa – PersonEntity: Name: NameFull: Miggino, Marco – PersonEntity: Name: NameFull: Andorno, Enzo – PersonEntity: Name: NameFull: Porcile, Elisa – PersonEntity: Name: NameFull: Resaz, Martina – PersonEntity: Name: NameFull: Roccatagliata, Luca – PersonEntity: Name: NameFull: Castellan, Lucio – PersonEntity: Name: NameFull: Villani, Flavio – PersonEntity: Name: NameFull: Ferrari, Alessandra IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 15901874 Numbering: – Type: volume Value: 45 – Type: issue Value: 10 Titles: – TitleFull: Neurological Sciences Type: main |
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