View in EDS HTML Full Text PDF Full Text

Inducing ipsilateral motor‐evoked potentials in the biceps brachii muscle in healthy humans.

Saved in:
Bibliographic Details
Title: Inducing ipsilateral motor‐evoked potentials in the biceps brachii muscle in healthy humans.
Authors: Hu, Nijia (AUTHOR), Tanel, Meghan (AUTHOR), Baker, Stuart N. (AUTHOR), Kidgell, Dawson J. (AUTHOR), Walker, Simon (AUTHOR)
Source: European Journal of Neuroscience. Nov2024, Vol. 60 Issue 9, p6291-6299. 9p.
Subjects: Transcranial magnetic stimulation, Action potentials, Intraclass correlation, Young adults, Strength training
Abstract: To assess reticulospinal tract excitability, high‐intensity transcranial magnetic stimulation (TMS) has been used to elicit ipsilateral motor‐evoked potentials (iMEPs). However, there is no consensus on robust and valid methods for use in human studies. The present study proposes a standardized method for eliciting and analysing iMEPs in the biceps brachii. Twenty‐four healthy young adults participated in this study. Electromyography (EMG) electrodes recorded contralateral MEPs (cMEPs) from the right and iMEPs from the left biceps brachii. A dynamic preacher curl task was used with ~15% of the subject's one‐repetition maximum load. The protocol included maximal compound action potential (M‐max) determination of the right biceps brachii muscle, TMS hotspot determination, and four sets of five repetitions where 100% stimulator output was delivered at an elbow angle of 110° of flexion. We normalized cMEP amplitude by M‐max (% M‐max) and iMEP by cMEP amplitude ratio (ICAR). Clear iMEPs above background EMG were observed in 21 subjects (88%, ICAR =.31 ±.19). Good‐to‐excellent agreement (intraclass correlation coefficient [ICC] =.795–1.000) and low bias (.01–.08 mV and.60–1.11 ms) were demonstrated when comparing two different analysis methods (i.e. fixed time‐window vs. manual onset detection) to determine the cMEP and iMEP amplitude and latency, respectively. Most subjects demonstrated clear iMEPs above background EMG triggered at a pre‐determined joint angle during a light‐load dynamic preacher curl exercise. Similar results were obtained when comparing a single‐trial manual identification of iMEP and a semi‐automated time‐window data analysis approach. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 180655426
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Inducing ipsilateral motor‐evoked potentials in the biceps brachii muscle in healthy humans.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Hu%2C+Nijia%22">Hu, Nijia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tanel%2C+Meghan%22">Tanel, Meghan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Baker%2C+Stuart+N%2E%22">Baker, Stuart N.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kidgell%2C+Dawson+J%2E%22">Kidgell, Dawson J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Walker%2C+Simon%22">Walker, Simon</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neuroscience%22">European Journal of Neuroscience</searchLink>. Nov2024, Vol. 60 Issue 9, p6291-6299. 9p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Transcranial+magnetic+stimulation%22">Transcranial magnetic stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Action+potentials%22">Action potentials</searchLink><br /><searchLink fieldCode="DE" term="%22Intraclass+correlation%22">Intraclass correlation</searchLink><br /><searchLink fieldCode="DE" term="%22Young+adults%22">Young adults</searchLink><br /><searchLink fieldCode="DE" term="%22Strength+training%22">Strength training</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: To assess reticulospinal tract excitability, high‐intensity transcranial magnetic stimulation (TMS) has been used to elicit ipsilateral motor‐evoked potentials (iMEPs). However, there is no consensus on robust and valid methods for use in human studies. The present study proposes a standardized method for eliciting and analysing iMEPs in the biceps brachii. Twenty‐four healthy young adults participated in this study. Electromyography (EMG) electrodes recorded contralateral MEPs (cMEPs) from the right and iMEPs from the left biceps brachii. A dynamic preacher curl task was used with ~15% of the subject's one‐repetition maximum load. The protocol included maximal compound action potential (M‐max) determination of the right biceps brachii muscle, TMS hotspot determination, and four sets of five repetitions where 100% stimulator output was delivered at an elbow angle of 110° of flexion. We normalized cMEP amplitude by M‐max (% M‐max) and iMEP by cMEP amplitude ratio (ICAR). Clear iMEPs above background EMG were observed in 21 subjects (88%, ICAR =.31 ±.19). Good‐to‐excellent agreement (intraclass correlation coefficient [ICC] =.795–1.000) and low bias (.01–.08 mV and.60–1.11 ms) were demonstrated when comparing two different analysis methods (i.e. fixed time‐window vs. manual onset detection) to determine the cMEP and iMEP amplitude and latency, respectively. Most subjects demonstrated clear iMEPs above background EMG triggered at a pre‐determined joint angle during a light‐load dynamic preacher curl exercise. Similar results were obtained when comparing a single‐trial manual identification of iMEP and a semi‐automated time‐window data analysis approach. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=180655426
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/ejn.16548
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 6291
    Subjects:
      – SubjectFull: Transcranial magnetic stimulation
        Type: general
      – SubjectFull: Action potentials
        Type: general
      – SubjectFull: Intraclass correlation
        Type: general
      – SubjectFull: Young adults
        Type: general
      – SubjectFull: Strength training
        Type: general
    Titles:
      – TitleFull: Inducing ipsilateral motor‐evoked potentials in the biceps brachii muscle in healthy humans.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hu, Nijia
      – PersonEntity:
          Name:
            NameFull: Tanel, Meghan
      – PersonEntity:
          Name:
            NameFull: Baker, Stuart N.
      – PersonEntity:
          Name:
            NameFull: Kidgell, Dawson J.
      – PersonEntity:
          Name:
            NameFull: Walker, Simon
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: Nov2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 0953816X
          Numbering:
            – Type: volume
              Value: 60
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: European Journal of Neuroscience
              Type: main
ResultId 1