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Cerebral venous thrombosis in elderly patients.

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Title: Cerebral venous thrombosis in elderly patients.
Authors: Garcia, Victor (AUTHOR), Bicart‐Sée, Louise (AUTHOR), Crassard, Isabelle (AUTHOR), Legris, Nicolas (AUTHOR), Zuber, Mathieu (AUTHOR), Pico, Fernando (AUTHOR), Guidoux, Céline (AUTHOR), Obadia, Michael (AUTHOR), Boulenoir, Naouel (AUTHOR), Smadja, Didier (AUTHOR), Mazighi, Mikael (AUTHOR), Lavenu‐Bombled, Cecile (AUTHOR), Baudry, Elodie (AUTHOR), Lapergue, Bertrand (AUTHOR), Turc, Guillaume (AUTHOR), Tuppin, Philippe (AUTHOR), Denier, Christian (AUTHOR)
Source: European Journal of Neurology. Dec2024, Vol. 31 Issue 12, p1-10. 10p.
Subjects: Older people, Older patients, Cerebral embolism & thrombosis, Venous thrombosis, Symptoms
Abstract: Background and purpose: We aimed to report the characteristics of cerebral venous thrombosis (CVT) in elderly people (aged ≥65 years). Methods: This multicenter retrospective cohort included elderly patients hospitalized for a first CVT in nine Paris–Ile‐de‐France hospitals between 2011 and 2021. The estimated incidence was compared to CVT recorded by the French health insurance data system. Lariboisière Hospital's CVT registry allowed comparisons of our elderly cohort with individuals younger than 65 years. Results: One hundred fourteen patients were included in this study (mean age = 74.2 years, range = 65–93, 61% female). The CVT annual incidence in Ile‐de‐France was 5.9–7.1 per million elderly individuals versus 8.5 per million nationwide. Headaches and focal deficits were the most common initial clinical features (50% and 51%, respectively), followed by seizures and confusion (40% and 27%). Treatment included anticoagulation (93%) and, rarely, endovascular procedure (2%) or craniectomy (1%). Compared with adult patients aged <65 years (younger adults), elderly patients presented fewer headaches (50% vs. 96%, p < 0.01) and intracranial hypertension (7% vs. 22%, p < 0.01) but more seizures and focal deficits (40% vs. 27% and 51% vs. 38%, respectively, p < 0.01). Underlying cancer, hemopathy, and locoregional infections were more frequent in elderly patients than among younger adults (p < 0.01). The prognosis of patients from our elderly cohort was poorer than that of younger adults; 8% died in the acute phase, and 73% had a favorable outcome at 1 year (vs. 1.7% and 87%, respectively, p < 0.01). Conclusions: CVT in elderly patients has a specific clinical presentation, epidemiology, and risk factors such as cancer or hemopathy, justifying specialized management. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Cerebral venous thrombosis in elderly patients.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Garcia%2C+Victor%22&quot;&gt;Garcia, Victor&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bicart‐S&#233;e%2C+Louise%22&quot;&gt;Bicart‐S&#233;e, Louise&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Crassard%2C+Isabelle%22&quot;&gt;Crassard, Isabelle&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Legris%2C+Nicolas%22&quot;&gt;Legris, Nicolas&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zuber%2C+Mathieu%22&quot;&gt;Zuber, Mathieu&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pico%2C+Fernando%22&quot;&gt;Pico, Fernando&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Guidoux%2C+C&#233;line%22&quot;&gt;Guidoux, C&#233;line&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Obadia%2C+Michael%22&quot;&gt;Obadia, Michael&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Boulenoir%2C+Naouel%22&quot;&gt;Boulenoir, Naouel&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Smadja%2C+Didier%22&quot;&gt;Smadja, Didier&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mazighi%2C+Mikael%22&quot;&gt;Mazighi, Mikael&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lavenu‐Bombled%2C+Cecile%22&quot;&gt;Lavenu‐Bombled, Cecile&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Baudry%2C+Elodie%22&quot;&gt;Baudry, Elodie&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lapergue%2C+Bertrand%22&quot;&gt;Lapergue, Bertrand&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Turc%2C+Guillaume%22&quot;&gt;Turc, Guillaume&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tuppin%2C+Philippe%22&quot;&gt;Tuppin, Philippe&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Denier%2C+Christian%22&quot;&gt;Denier, Christian&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neurology%22&quot;&gt;European Journal of Neurology&lt;/searchLink&gt;. Dec2024, Vol. 31 Issue 12, p1-10. 10p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Older+people%22&quot;&gt;Older people&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Older+patients%22&quot;&gt;Older patients&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cerebral+embolism+%26+thrombosis%22&quot;&gt;Cerebral embolism &amp; thrombosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Venous+thrombosis%22&quot;&gt;Venous thrombosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Symptoms%22&quot;&gt;Symptoms&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background and purpose: We aimed to report the characteristics of cerebral venous thrombosis (CVT) in elderly people (aged ≥65 years). Methods: This multicenter retrospective cohort included elderly patients hospitalized for a first CVT in nine Paris–Ile‐de‐France hospitals between 2011 and 2021. The estimated incidence was compared to CVT recorded by the French health insurance data system. Lariboisi&#232;re Hospital&#39;s CVT registry allowed comparisons of our elderly cohort with individuals younger than 65 years. Results: One hundred fourteen patients were included in this study (mean age = 74.2 years, range = 65–93, 61% female). The CVT annual incidence in Ile‐de‐France was 5.9–7.1 per million elderly individuals versus 8.5 per million nationwide. Headaches and focal deficits were the most common initial clinical features (50% and 51%, respectively), followed by seizures and confusion (40% and 27%). Treatment included anticoagulation (93%) and, rarely, endovascular procedure (2%) or craniectomy (1%). Compared with adult patients aged &lt;65 years (younger adults), elderly patients presented fewer headaches (50% vs. 96%, p &lt; 0.01) and intracranial hypertension (7% vs. 22%, p &lt; 0.01) but more seizures and focal deficits (40% vs. 27% and 51% vs. 38%, respectively, p &lt; 0.01). Underlying cancer, hemopathy, and locoregional infections were more frequent in elderly patients than among younger adults (p &lt; 0.01). The prognosis of patients from our elderly cohort was poorer than that of younger adults; 8% died in the acute phase, and 73% had a favorable outcome at 1 year (vs. 1.7% and 87%, respectively, p &lt; 0.01). Conclusions: CVT in elderly patients has a specific clinical presentation, epidemiology, and risk factors such as cancer or hemopathy, justifying specialized management. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=180827623
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        Value: 10.1111/ene.16504
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      – Code: eng
        Text: English
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        PageCount: 10
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    Subjects:
      – SubjectFull: Older people
        Type: general
      – SubjectFull: Older patients
        Type: general
      – SubjectFull: Cerebral embolism & thrombosis
        Type: general
      – SubjectFull: Venous thrombosis
        Type: general
      – SubjectFull: Symptoms
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      – TitleFull: Cerebral venous thrombosis in elderly patients.
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              Text: Dec2024
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