Examining HIV pre-exposure prophylaxis (PrEP) acceptability among rural people who inject drugs: predictors of PrEP interest among syringe service program clients.

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Title: Examining HIV pre-exposure prophylaxis (PrEP) acceptability among rural people who inject drugs: predictors of PrEP interest among syringe service program clients.
Authors: Surratt, Hilary L., Brown, Sarah, Burton, Abby L., Cranford, Will, Green, Christie, Mersch, Stephanie M., Rains, Rebecca, Westgate, Philip M.
Source: AIDS Care. Dec2024, Vol. 36 Issue 12, p1858-1868. 11p.
Subjects: HIV prevention, Needle exchange programs, Research funding, Social determinants of health, Interviewing, Descriptive statistics, Pre-exposure prophylaxis, Rural conditions, Research methodology, Patients' attitudes, Intravenous drug abusers, Psychosocial factors, Community-based social services, Social stigma
Geographic Terms: Kentucky
Abstract: Rural communities in the US have increasing HIV burden tied to injection drug use, yet engagement in pre-exposure prophylaxis (PrEP) care has been low among people who inject drugs (PWID). Syringe service programs (SSPs) are widely implemented in Kentucky's Appalachian region, presenting an important opportunity to scale PrEP services. This paper examines PrEP awareness, interest and preferences among PWID attending community-based SSPs in Appalachia. Eighty participants were enrolled from two SSP locations. Eligibility included: ≥ 18 years old, current injection drug use and SSP use, and an indication for PrEP as defined by CDC guidelines. Participants completed a structured baseline interview. Predictors of PrEP awareness, interest and formulation preferences were examined. 38.8% reported baseline awareness of PrEP, 50% expressed high interest in PrEP, and 48.1%reported a preference for injectable PrEP. Significant bivariate predictors of PrEP interest included: current worry about health, higher perceived HIV risk, higher community HIV stigma, and higher enacted substance use stigma in the past year; in the adjusted model, enacted substance use stigma remained significant. Findings demonstrate substantial interest in PrEP among rural PWID. Intrapersonal and social determinant factors were associated with PrEP interest, which suggests the importance of multi-level intervention targets to increase PrEP uptake. [ABSTRACT FROM AUTHOR]
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  Data: Examining HIV pre-exposure prophylaxis (PrEP) acceptability among rural people who inject drugs: predictors of PrEP interest among syringe service program clients.
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  Data: <searchLink fieldCode="AR" term="%22Surratt%2C+Hilary+L%2E%22">Surratt, Hilary L.</searchLink><br /><searchLink fieldCode="AR" term="%22Brown%2C+Sarah%22">Brown, Sarah</searchLink><br /><searchLink fieldCode="AR" term="%22Burton%2C+Abby+L%2E%22">Burton, Abby L.</searchLink><br /><searchLink fieldCode="AR" term="%22Cranford%2C+Will%22">Cranford, Will</searchLink><br /><searchLink fieldCode="AR" term="%22Green%2C+Christie%22">Green, Christie</searchLink><br /><searchLink fieldCode="AR" term="%22Mersch%2C+Stephanie+M%2E%22">Mersch, Stephanie M.</searchLink><br /><searchLink fieldCode="AR" term="%22Rains%2C+Rebecca%22">Rains, Rebecca</searchLink><br /><searchLink fieldCode="AR" term="%22Westgate%2C+Philip+M%2E%22">Westgate, Philip M.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Dec2024, Vol. 36 Issue 12, p1858-1868. 11p.
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  Data: <searchLink fieldCode="DE" term="%22HIV+prevention%22">HIV prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Needle+exchange+programs%22">Needle exchange programs</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Social+determinants+of+health%22">Social determinants of health</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Pre-exposure+prophylaxis%22">Pre-exposure prophylaxis</searchLink><br /><searchLink fieldCode="DE" term="%22Rural+conditions%22">Rural conditions</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Patients'+attitudes%22">Patients' attitudes</searchLink><br /><searchLink fieldCode="DE" term="%22Intravenous+drug+abusers%22">Intravenous drug abusers</searchLink><br /><searchLink fieldCode="DE" term="%22Psychosocial+factors%22">Psychosocial factors</searchLink><br /><searchLink fieldCode="DE" term="%22Community-based+social+services%22">Community-based social services</searchLink><br /><searchLink fieldCode="DE" term="%22Social+stigma%22">Social stigma</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Kentucky%22">Kentucky</searchLink>
– Name: Abstract
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  Data: Rural communities in the US have increasing HIV burden tied to injection drug use, yet engagement in pre-exposure prophylaxis (PrEP) care has been low among people who inject drugs (PWID). Syringe service programs (SSPs) are widely implemented in Kentucky's Appalachian region, presenting an important opportunity to scale PrEP services. This paper examines PrEP awareness, interest and preferences among PWID attending community-based SSPs in Appalachia. Eighty participants were enrolled from two SSP locations. Eligibility included: ≥ 18 years old, current injection drug use and SSP use, and an indication for PrEP as defined by CDC guidelines. Participants completed a structured baseline interview. Predictors of PrEP awareness, interest and formulation preferences were examined. 38.8% reported baseline awareness of PrEP, 50% expressed high interest in PrEP, and 48.1%reported a preference for injectable PrEP. Significant bivariate predictors of PrEP interest included: current worry about health, higher perceived HIV risk, higher community HIV stigma, and higher enacted substance use stigma in the past year; in the adjusted model, enacted substance use stigma remained significant. Findings demonstrate substantial interest in PrEP among rural PWID. Intrapersonal and social determinant factors were associated with PrEP interest, which suggests the importance of multi-level intervention targets to increase PrEP uptake. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2024.2390067
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 1858
    Subjects:
      – SubjectFull: HIV prevention
        Type: general
      – SubjectFull: Needle exchange programs
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Social determinants of health
        Type: general
      – SubjectFull: Interviewing
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Pre-exposure prophylaxis
        Type: general
      – SubjectFull: Rural conditions
        Type: general
      – SubjectFull: Research methodology
        Type: general
      – SubjectFull: Patients' attitudes
        Type: general
      – SubjectFull: Intravenous drug abusers
        Type: general
      – SubjectFull: Psychosocial factors
        Type: general
      – SubjectFull: Community-based social services
        Type: general
      – SubjectFull: Social stigma
        Type: general
      – SubjectFull: Kentucky
        Type: general
    Titles:
      – TitleFull: Examining HIV pre-exposure prophylaxis (PrEP) acceptability among rural people who inject drugs: predictors of PrEP interest among syringe service program clients.
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            – D: 01
              M: 12
              Text: Dec2024
              Type: published
              Y: 2024
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