Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study.
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| Title: | Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study. |
|---|---|
| Authors: | Reuken, P. A. (AUTHOR), Besteher, B. (AUTHOR), Finke, K. (AUTHOR), Fischer, A. (AUTHOR), Holl, A. (AUTHOR), Katzer, K. (AUTHOR), Lehmann-Pohl, K. (AUTHOR), Lemhöfer, C. (AUTHOR), Nowka, M. (AUTHOR), Puta, C. (AUTHOR), Walter, M. (AUTHOR), Weißenborn, C. (AUTHOR), Stallmach, A. (AUTHOR) |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. Dec2024, Vol. 274 Issue 8, p1903-1910. 8p. |
| Subjects: | Post-acute COVID-19 syndrome, COVID-19 pandemic, Reporting of diseases, COVID-19, SARS-CoV-2 |
| Abstract: | A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority of patients complains about neuropsychological symptoms. Additionally, a subgroup of patients fulfills diagnostic criteria for ME/CFS. We analyzed a registry of all patients presenting in the out-patients clinic at a German university center. For patients with more than one visit, changes in reported symptoms from first to second visit were analyzed. A total of 1022 patients were included in the study, 411 of them had more than one visit. 95.5% of the patients reported a polysymptomatic disease. At the first visit 31.3% of the patients fulfilled ME/CFS criteria after a median time of 255 days post infection and and at the second visit after a median of 402 days, 19.4% still suffered from ME/CFS. Self-reported fatigue (83.7–72.7%) and concentration impairment (66.2–57.9%) decreased from first to second visit contrasting non-significant changes in the structured screening. A significant proportion of SARS-CoV-2 survivors presenting with ongoing symptoms present with ME/CFS. Although the proportion of subjective reported symptoms and their severity reduce over time, a significant proportion of patients suffer from long-lasting symptoms necessitating new therapeutic concepts. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 180988863 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Reuken%2C+P%2E+A%2E%22">Reuken, P. A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Besteher%2C+B%2E%22">Besteher, B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Finke%2C+K%2E%22">Finke, K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fischer%2C+A%2E%22">Fischer, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Holl%2C+A%2E%22">Holl, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Katzer%2C+K%2E%22">Katzer, K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lehmann-Pohl%2C+K%2E%22">Lehmann-Pohl, K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lemhöfer%2C+C%2E%22">Lemhöfer, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nowka%2C+M%2E%22">Nowka, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Puta%2C+C%2E%22">Puta, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Walter%2C+M%2E%22">Walter, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Weißenborn%2C+C%2E%22">Weißenborn, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stallmach%2C+A%2E%22">Stallmach, A.</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. Dec2024, Vol. 274 Issue 8, p1903-1910. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Post-acute+COVID-19+syndrome%22">Post-acute COVID-19 syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19+pandemic%22">COVID-19 pandemic</searchLink><br /><searchLink fieldCode="DE" term="%22Reporting+of+diseases%22">Reporting of diseases</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19%22">COVID-19</searchLink><br /><searchLink fieldCode="DE" term="%22SARS-CoV-2%22">SARS-CoV-2</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: A significant proportion of patients after SARS-CoV-2 infection suffer from long-lasting symptoms. Although many different symptoms are described, the majority of patients complains about neuropsychological symptoms. Additionally, a subgroup of patients fulfills diagnostic criteria for ME/CFS. We analyzed a registry of all patients presenting in the out-patients clinic at a German university center. For patients with more than one visit, changes in reported symptoms from first to second visit were analyzed. A total of 1022 patients were included in the study, 411 of them had more than one visit. 95.5% of the patients reported a polysymptomatic disease. At the first visit 31.3% of the patients fulfilled ME/CFS criteria after a median time of 255 days post infection and and at the second visit after a median of 402 days, 19.4% still suffered from ME/CFS. Self-reported fatigue (83.7–72.7%) and concentration impairment (66.2–57.9%) decreased from first to second visit contrasting non-significant changes in the structured screening. A significant proportion of SARS-CoV-2 survivors presenting with ongoing symptoms present with ME/CFS. Although the proportion of subjective reported symptoms and their severity reduce over time, a significant proportion of patients suffer from long-lasting symptoms necessitating new therapeutic concepts. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00406-023-01661-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 1903 Subjects: – SubjectFull: Post-acute COVID-19 syndrome Type: general – SubjectFull: COVID-19 pandemic Type: general – SubjectFull: Reporting of diseases Type: general – SubjectFull: COVID-19 Type: general – SubjectFull: SARS-CoV-2 Type: general Titles: – TitleFull: Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Reuken, P. A. – PersonEntity: Name: NameFull: Besteher, B. – PersonEntity: Name: NameFull: Finke, K. – PersonEntity: Name: NameFull: Fischer, A. – PersonEntity: Name: NameFull: Holl, A. – PersonEntity: Name: NameFull: Katzer, K. – PersonEntity: Name: NameFull: Lehmann-Pohl, K. – PersonEntity: Name: NameFull: Lemhöfer, C. – PersonEntity: Name: NameFull: Nowka, M. – PersonEntity: Name: NameFull: Puta, C. – PersonEntity: Name: NameFull: Walter, M. – PersonEntity: Name: NameFull: Weißenborn, C. – PersonEntity: Name: NameFull: Stallmach, A. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 274 – Type: issue Value: 8 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
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