Mechanisms of axon ensheathment and myelin growth.
Saved in:
| Title: | Mechanisms of axon ensheathment and myelin growth. |
|---|---|
| Authors: | Sherman, Diane L., Brophy, Peter J. |
| Source: | Nature Reviews Neuroscience. Sep2005, Vol. 6 Issue 9, p683-690. 8p. 3 Diagrams. |
| Subjects: | Myelin sheath, Cell membranes, Myelination, Nerve tissue, Axons, Nervous system |
| Abstract: | The evolution of complex nervous systems in vertebrates has been accompanied by, and probably dependent on, the acquisition of the myelin sheath. Although there has been substantial progress in our understanding of the factors that determine glial cell fate, much less is known about the cellular mechanisms that determine how the myelin sheath is extended and stabilized around axons. This review highlights four crucial stages of myelination, namely, the selection of axons and initiation of cell-cell interactions between them and glial cells, the establishment of stable intercellular contact and assembly of the nodes of Ranvier, regulation of myelin thickness and, finally, longitudinal extension of myelin segments in response to the lengthening of axons during postnatal growth. [ABSTRACT FROM AUTHOR] |
| Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 18125128 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Mechanisms of axon ensheathment and myelin growth. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sherman%2C+Diane+L%2E%22">Sherman, Diane L.</searchLink><br /><searchLink fieldCode="AR" term="%22Brophy%2C+Peter+J%2E%22">Brophy, Peter J.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nature+Reviews+Neuroscience%22">Nature Reviews Neuroscience</searchLink>. Sep2005, Vol. 6 Issue 9, p683-690. 8p. 3 Diagrams. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Myelin+sheath%22">Myelin sheath</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+membranes%22">Cell membranes</searchLink><br /><searchLink fieldCode="DE" term="%22Myelination%22">Myelination</searchLink><br /><searchLink fieldCode="DE" term="%22Nerve+tissue%22">Nerve tissue</searchLink><br /><searchLink fieldCode="DE" term="%22Axons%22">Axons</searchLink><br /><searchLink fieldCode="DE" term="%22Nervous+system%22">Nervous system</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The evolution of complex nervous systems in vertebrates has been accompanied by, and probably dependent on, the acquisition of the myelin sheath. Although there has been substantial progress in our understanding of the factors that determine glial cell fate, much less is known about the cellular mechanisms that determine how the myelin sheath is extended and stabilized around axons. This review highlights four crucial stages of myelination, namely, the selection of axons and initiation of cell-cell interactions between them and glial cells, the establishment of stable intercellular contact and assembly of the nodes of Ranvier, regulation of myelin thickness and, finally, longitudinal extension of myelin segments in response to the lengthening of axons during postnatal growth. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=18125128 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/nrn1743 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 683 Subjects: – SubjectFull: Myelin sheath Type: general – SubjectFull: Cell membranes Type: general – SubjectFull: Myelination Type: general – SubjectFull: Nerve tissue Type: general – SubjectFull: Axons Type: general – SubjectFull: Nervous system Type: general Titles: – TitleFull: Mechanisms of axon ensheathment and myelin growth. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sherman, Diane L. – PersonEntity: Name: NameFull: Brophy, Peter J. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2005 Type: published Y: 2005 Identifiers: – Type: issn-print Value: 1471003X Numbering: – Type: volume Value: 6 – Type: issue Value: 9 Titles: – TitleFull: Nature Reviews Neuroscience Type: main |
| ResultId | 1 |
