Comparing the effectiveness of CBT and low-frequency rTMS in reducing symptom severity and depression and improving working memory in adults with OCD: a clinical trial.
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| Title: | Comparing the effectiveness of CBT and low-frequency rTMS in reducing symptom severity and depression and improving working memory in adults with OCD: a clinical trial. |
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| Authors: | Fazeli, Arash (AUTHOR), Zolghadriha, Ahmad (AUTHOR), Pirzeh, Reza (AUTHOR), Fatehi Chenar, Atefeh (AUTHOR), Dadashi, Mohsen (AUTHOR) |
| Source: | International Journal of Neuroscience. Dec2024, Vol. 134 Issue 12, p1635-1646. 12p. |
| Subjects: | Hamilton Depression Inventory, Transcranial magnetic stimulation, Cognitive therapy, Short-term memory, Clinical trials |
| Abstract: | Objective: This study aims to compare the effectiveness of cognitive-behavioral therapy (CBT) and low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) in reducing symptom severity and depression and improving working memory in adults with obsessive–compulsive disorder (OCD). Methods: This is a randomized clinical trial conducted on 24 adults with OCD, randomly assigned into two groups of CBT (n = 12, received CBT with exposure and response prevention (ERP) individually at 20 sessions) and rTMS (n = 12, received LF (1-Hz) rTMS over the right dorsolateral prefrontal cortex (DLPFC) at 10 sessions). They completed the Yale-Brown Obsessive Compulsive Scale, the Hamilton Depression Rating Scale, and two N-Back tasks before, immediately, and 1 month after interventions. Results: Results showed a significant difference between the two methods in reducing the severity of OCD symptoms (p < 0.05) and depression (p = 0.002) immediately after interventions where the CBT with ERP was more effective, but no significant difference was found in terms of working memory (p > 0.05). No significant difference was found between groups in any study variables 1 month after interventions. Conclusion: Individual CBT with ERP is superior to LF rTMS for reducing the severity of symptoms and depression in OCD patients. However, there is no difference between them in improving working memory. [ABSTRACT FROM AUTHOR] |
| Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 181550510 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparing the effectiveness of CBT and low-frequency rTMS in reducing symptom severity and depression and improving working memory in adults with OCD: a clinical trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fazeli%2C+Arash%22">Fazeli, Arash</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zolghadriha%2C+Ahmad%22">Zolghadriha, Ahmad</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pirzeh%2C+Reza%22">Pirzeh, Reza</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fatehi+Chenar%2C+Atefeh%22">Fatehi Chenar, Atefeh</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dadashi%2C+Mohsen%22">Dadashi, Mohsen</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Neuroscience%22">International Journal of Neuroscience</searchLink>. Dec2024, Vol. 134 Issue 12, p1635-1646. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Hamilton+Depression+Inventory%22">Hamilton Depression Inventory</searchLink><br /><searchLink fieldCode="DE" term="%22Transcranial+magnetic+stimulation%22">Transcranial magnetic stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Short-term+memory%22">Short-term memory</searchLink><br /><searchLink fieldCode="DE" term="%22Clinical+trials%22">Clinical trials</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective: This study aims to compare the effectiveness of cognitive-behavioral therapy (CBT) and low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) in reducing symptom severity and depression and improving working memory in adults with obsessive–compulsive disorder (OCD). Methods: This is a randomized clinical trial conducted on 24 adults with OCD, randomly assigned into two groups of CBT (n = 12, received CBT with exposure and response prevention (ERP) individually at 20 sessions) and rTMS (n = 12, received LF (1-Hz) rTMS over the right dorsolateral prefrontal cortex (DLPFC) at 10 sessions). They completed the Yale-Brown Obsessive Compulsive Scale, the Hamilton Depression Rating Scale, and two N-Back tasks before, immediately, and 1 month after interventions. Results: Results showed a significant difference between the two methods in reducing the severity of OCD symptoms (p < 0.05) and depression (p = 0.002) immediately after interventions where the CBT with ERP was more effective, but no significant difference was found in terms of working memory (p > 0.05). No significant difference was found between groups in any study variables 1 month after interventions. Conclusion: Individual CBT with ERP is superior to LF rTMS for reducing the severity of symptoms and depression in OCD patients. However, there is no difference between them in improving working memory. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of International Journal of Neuroscience is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/00207454.2023.2279500 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 1635 Subjects: – SubjectFull: Hamilton Depression Inventory Type: general – SubjectFull: Transcranial magnetic stimulation Type: general – SubjectFull: Cognitive therapy Type: general – SubjectFull: Short-term memory Type: general – SubjectFull: Clinical trials Type: general Titles: – TitleFull: Comparing the effectiveness of CBT and low-frequency rTMS in reducing symptom severity and depression and improving working memory in adults with OCD: a clinical trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fazeli, Arash – PersonEntity: Name: NameFull: Zolghadriha, Ahmad – PersonEntity: Name: NameFull: Pirzeh, Reza – PersonEntity: Name: NameFull: Fatehi Chenar, Atefeh – PersonEntity: Name: NameFull: Dadashi, Mohsen IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 00207454 Numbering: – Type: volume Value: 134 – Type: issue Value: 12 Titles: – TitleFull: International Journal of Neuroscience Type: main |
| ResultId | 1 |
