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Effect of depressive symptoms on health services utilization in the HIV and hepatitis C co-infected population in Canada.

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Title: Effect of depressive symptoms on health services utilization in the HIV and hepatitis C co-infected population in Canada.
Authors: Marathe, Gayatri, Moodie, Erica EM, Brouillette, Marie-Josée, Delaunay, Charlotte Lanièce, Cox, Joseph, Cooper, Curtis, Martel-Laferrière, Valérie, Hull, Mark, Wong, Alexander, Walmsley, Sharon, Klein, Marina B.
Source: AIDS Care. Feb2025, Vol. 37 Issue 2, p226-232. 7p.
Subjects: Medical care use, Self-evaluation, Random forest algorithms, Viral load, Center for Epidemiologic Studies Depression Scale, Research funding, Descriptive statistics, Psychology of HIV-positive persons, Antiviral agents, Longitudinal method, Research, Hepatitis C, Psychological tests, Sociodemographic factors, Confidence intervals, Data analysis software, Mental depression, Mixed infections
Geographic Terms: Canada
Abstract: Depression is common among people living with HCV and HIV, which contributes to health services utilization (HSU). It is unknown whether successful HCV treatment affects this. We examined depressive symptoms and HSU in people co-infected with HIV-HCV and their association with sustained virologic response (SVR) during the direct-acting antiviral era. We predicted depressive symptoms by a random forest classifier in the Canadian Co-infection Cohort. HSU was measured by inpatient and out-patient visits in the previous six months. We fit zero-inflated negative binomial models. Of the 1153 HCV RNA+participants, 530 were treated and of them, 95% achieved SVR. Without SVR, inpatient and out-patient visits were 17% and 5% higher among those with depressive symptoms than those without respectively; with SVR, this association disappeared. SVR was associated with 24% fewer inpatient visits. Thus, depressive symptoms were associated with a modest increase in HSU, and SVR appears to attenuate this effect. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Effect of depressive symptoms on health services utilization in the HIV and hepatitis C co-infected population in Canada.
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  Data: <searchLink fieldCode="AR" term="%22Marathe%2C+Gayatri%22">Marathe, Gayatri</searchLink><br /><searchLink fieldCode="AR" term="%22Moodie%2C+Erica+EM%22">Moodie, Erica EM</searchLink><br /><searchLink fieldCode="AR" term="%22Brouillette%2C+Marie-Josée%22">Brouillette, Marie-Josée</searchLink><br /><searchLink fieldCode="AR" term="%22Delaunay%2C+Charlotte+Lanièce%22">Delaunay, Charlotte Lanièce</searchLink><br /><searchLink fieldCode="AR" term="%22Cox%2C+Joseph%22">Cox, Joseph</searchLink><br /><searchLink fieldCode="AR" term="%22Cooper%2C+Curtis%22">Cooper, Curtis</searchLink><br /><searchLink fieldCode="AR" term="%22Martel-Laferrière%2C+Valérie%22">Martel-Laferrière, Valérie</searchLink><br /><searchLink fieldCode="AR" term="%22Hull%2C+Mark%22">Hull, Mark</searchLink><br /><searchLink fieldCode="AR" term="%22Wong%2C+Alexander%22">Wong, Alexander</searchLink><br /><searchLink fieldCode="AR" term="%22Walmsley%2C+Sharon%22">Walmsley, Sharon</searchLink><br /><searchLink fieldCode="AR" term="%22Klein%2C+Marina+B%2E%22">Klein, Marina B.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Feb2025, Vol. 37 Issue 2, p226-232. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Canada%22">Canada</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Depression is common among people living with HCV and HIV, which contributes to health services utilization (HSU). It is unknown whether successful HCV treatment affects this. We examined depressive symptoms and HSU in people co-infected with HIV-HCV and their association with sustained virologic response (SVR) during the direct-acting antiviral era. We predicted depressive symptoms by a random forest classifier in the Canadian Co-infection Cohort. HSU was measured by inpatient and out-patient visits in the previous six months. We fit zero-inflated negative binomial models. Of the 1153 HCV RNA+participants, 530 were treated and of them, 95% achieved SVR. Without SVR, inpatient and out-patient visits were 17% and 5% higher among those with depressive symptoms than those without respectively; with SVR, this association disappeared. SVR was associated with 24% fewer inpatient visits. Thus, depressive symptoms were associated with a modest increase in HSU, and SVR appears to attenuate this effect. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2024.2432801
    Languages:
      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 226
    Subjects:
      – SubjectFull: Medical care use
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Random forest algorithms
        Type: general
      – SubjectFull: Viral load
        Type: general
      – SubjectFull: Center for Epidemiologic Studies Depression Scale
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Psychology of HIV-positive persons
        Type: general
      – SubjectFull: Antiviral agents
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Research
        Type: general
      – SubjectFull: Hepatitis C
        Type: general
      – SubjectFull: Psychological tests
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      – SubjectFull: Sociodemographic factors
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      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Data analysis software
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      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Mixed infections
        Type: general
      – SubjectFull: Canada
        Type: general
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      – TitleFull: Effect of depressive symptoms on health services utilization in the HIV and hepatitis C co-infected population in Canada.
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              Text: Feb2025
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