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Management of severe traumatic brain injury in pediatric patients: an evidence-based approach.

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Title: Management of severe traumatic brain injury in pediatric patients: an evidence-based approach.
Authors: de Carvalho Panzeri Carlotti, Ana Paula (AUTHOR), do Amaral, Vivian Henriques (AUTHOR), de Carvalho Canela Balzi, Ana Paula (AUTHOR), Johnston, Cintia (AUTHOR), Regalio, Fabiane Allioti (AUTHOR), Cardoso, Maíra Freire (AUTHOR), Ferranti, Juliana Ferreira (AUTHOR), Zamberlan, Patrícia (AUTHOR), Gilio, Alfredo Elias (AUTHOR), Malbouisson, Luiz Marcelo Sá (AUTHOR), Delgado, Artur Figueiredo (AUTHOR), de Carvalho, Werther Brunow (AUTHOR), Lahoz, Ana Lúcia Capelari (AUTHOR), Luglio, Michele (AUTHOR), dos Santos, Maria Lucia Barbosa Maia (AUTHOR), Góes, Patricia Freitas (AUTHOR), da Silva, Saul Almeida (AUTHOR), Paiva, Wellingson Silva (AUTHOR), Serafim, Alexandre Peixoto (AUTHOR), de Souza, Leonardo Calil Vicente Franco (AUTHOR)
Source: Neurological Sciences. Feb2025, Vol. 46 Issue 2, p969-991. 23p.
Subjects: Physicians, Brain injuries, Decompressive craniectomy, Child patients, Diet therapy
Abstract: Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. The decision-making process in the management of severe TBI must be based on the best available evidence to minimize the occurrence of secondary brain injuries. However, healthcare approaches to managing TBI patients exhibit considerable variation. Methods: Over an 18-month period, a multidisciplinary panel consisting of medical doctors, physiotherapists, nutritional therapists, and nurses performed a comprehensive review on various subtopics concerning TBI. The panel identified primary questions to be addressed using the Population, Intervention, Control, and Outcome (PICO) format and applied the Evidence to Decision (EtD) framework criteria for evaluating interventions. Subsequently, the panel formulated recommendations for the management of severe TBI in children. Results: Fourteen evidence-based recommendations have been devised for the management of severe TBI in children, covering nine topics, including imaging studies, neuromonitoring, prophylactic anticonvulsant use, hyperosmolar therapy, sedation and analgesia, mechanical ventilation strategies, nutritional therapy, blood transfusion, and decompressive craniectomy. For each topic, the panel provided clinical recommendations and identified research priorities. Conclusions: This review offers evidence-based strategies aimed to guide practitioners in the care of children who suffer from severe TBI. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. The decision-making process in the management of severe TBI must be based on the best available evidence to minimize the occurrence of secondary brain injuries. However, healthcare approaches to managing TBI patients exhibit considerable variation. Methods: Over an 18-month period, a multidisciplinary panel consisting of medical doctors, physiotherapists, nutritional therapists, and nurses performed a comprehensive review on various subtopics concerning TBI. The panel identified primary questions to be addressed using the Population, Intervention, Control, and Outcome (PICO) format and applied the Evidence to Decision (EtD) framework criteria for evaluating interventions. Subsequently, the panel formulated recommendations for the management of severe TBI in children. Results: Fourteen evidence-based recommendations have been devised for the management of severe TBI in children, covering nine topics, including imaging studies, neuromonitoring, prophylactic anticonvulsant use, hyperosmolar therapy, sedation and analgesia, mechanical ventilation strategies, nutritional therapy, blood transfusion, and decompressive craniectomy. For each topic, the panel provided clinical recommendations and identified research priorities. Conclusions: This review offers evidence-based strategies aimed to guide practitioners in the care of children who suffer from severe TBI. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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