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Childhood abuse and craving in methamphetamine-dependent individuals: the mediating role of alexithymia.

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Title: Childhood abuse and craving in methamphetamine-dependent individuals: the mediating role of alexithymia.
Authors: Chen, Jiajing (AUTHOR), Wang, Dong Mei (AUTHOR), Tian, Yang (AUTHOR), Zhu, Rongrong (AUTHOR), Li, Yuqing (AUTHOR), Jia, Lianglun (AUTHOR), Fu, Fabing (AUTHOR), Tang, Shanshan (AUTHOR), Wang, Xiaotao (AUTHOR), Wang, Li (AUTHOR), Zhang, Xiang Yang (AUTHOR)
Source: European Archives of Psychiatry & Clinical Neuroscience. Feb2025, Vol. 275 Issue 1, p209-217. 9p.
Subjects: Child abuse, Substance abuse, Adverse childhood experiences, Alexithymia, Desire
Abstract: Individuals with a history of childhood abuse (CA, including neglect and abuse by caregivers before the age of 18 years) have more severe substance dependence problems than those without a history of childhood abuse. However, whether a history of CA exacerbates craving and the mechanism of this effect remain largely unknown. The aim of this study was to explore the role of alexithymia in the effects of CA on craving in a large sample of methamphetamine-dependent individuals based on latent vulnerability theory. A total of 324 methamphetamine-dependent individuals who met DSM-5 criteria for substance use disorder were recruited. CA, alexithymia, and craving data were collected from the Childhood Trauma Questionnaire, the Toronto Alexithymia Scale-20, and the Obsessive Compulsive Drug Use Scale, respectively. t tests and ANCOVA were conducted to compare variables between the CA and non-CA groups, while partial correlation and mediation analyses were conducted to examine the potential mediating role of alexithymia in the relationship between CA and craving. Abused methamphetamine-dependent individuals reported higher levels of craving and higher levels of alexithymia than those of non-abused methamphetamine-dependent individuals. Alexithymia partially mediated the link between CA and craving, especially the effect of CA on craving frequency was fully mediated by alexithymia. Our findings reveal that a history of childhood abuse has a lasting effect on craving in stimulant-dependent individuals, and alexithymia contributes to some extent to the severity of substance abuse problems in abused methamphetamine-dependent individuals. [ABSTRACT FROM AUTHOR]
Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Childhood abuse and craving in methamphetamine-dependent individuals: the mediating role of alexithymia.
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  Data: <searchLink fieldCode="AR" term="%22Chen%2C+Jiajing%22">Chen, Jiajing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Dong+Mei%22">Wang, Dong Mei</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tian%2C+Yang%22">Tian, Yang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhu%2C+Rongrong%22">Zhu, Rongrong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Yuqing%22">Li, Yuqing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jia%2C+Lianglun%22">Jia, Lianglun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fu%2C+Fabing%22">Fu, Fabing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tang%2C+Shanshan%22">Tang, Shanshan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Xiaotao%22">Wang, Xiaotao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Li%22">Wang, Li</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Xiang+Yang%22">Zhang, Xiang Yang</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. Feb2025, Vol. 275 Issue 1, p209-217. 9p.
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  Data: <searchLink fieldCode="DE" term="%22Child+abuse%22">Child abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Substance+abuse%22">Substance abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Adverse+childhood+experiences%22">Adverse childhood experiences</searchLink><br /><searchLink fieldCode="DE" term="%22Alexithymia%22">Alexithymia</searchLink><br /><searchLink fieldCode="DE" term="%22Desire%22">Desire</searchLink>
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  Data: Individuals with a history of childhood abuse (CA, including neglect and abuse by caregivers before the age of 18 years) have more severe substance dependence problems than those without a history of childhood abuse. However, whether a history of CA exacerbates craving and the mechanism of this effect remain largely unknown. The aim of this study was to explore the role of alexithymia in the effects of CA on craving in a large sample of methamphetamine-dependent individuals based on latent vulnerability theory. A total of 324 methamphetamine-dependent individuals who met DSM-5 criteria for substance use disorder were recruited. CA, alexithymia, and craving data were collected from the Childhood Trauma Questionnaire, the Toronto Alexithymia Scale-20, and the Obsessive Compulsive Drug Use Scale, respectively. t tests and ANCOVA were conducted to compare variables between the CA and non-CA groups, while partial correlation and mediation analyses were conducted to examine the potential mediating role of alexithymia in the relationship between CA and craving. Abused methamphetamine-dependent individuals reported higher levels of craving and higher levels of alexithymia than those of non-abused methamphetamine-dependent individuals. Alexithymia partially mediated the link between CA and craving, especially the effect of CA on craving frequency was fully mediated by alexithymia. Our findings reveal that a history of childhood abuse has a lasting effect on craving in stimulant-dependent individuals, and alexithymia contributes to some extent to the severity of substance abuse problems in abused methamphetamine-dependent individuals. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Feb2025
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