View in EDS HTML Full Text PDF Full Text

Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study.

Saved in:
Bibliographic Details
Title: Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study.
Authors: Sarter, H. (AUTHOR), Kirschgesner, J. (AUTHOR), Beaugerie, L. (AUTHOR), Buisson, A. (AUTHOR), Gower-Rousseau, C. (AUTHOR), de Pouvourville, Gérard (AUTHOR)
Source: Quality of Life Research. Feb2025, Vol. 34 Issue 2, p405-416. 12p.
Subjects: Quality of life, Inflammatory bowel diseases, Visual analog scale, Ulcerative colitis, Crohn's disease, Patient reported outcome measures
Geographic Terms: France
Abstract: Purpose: This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Methods: QALY-MICI was a cross-sectional survey across three sources in France. Data were collected between 2019 and 2022 for patients 18 and over. The EQ-5D-5 L, the EQ-VAS, the Short Inflammatory Bowel Disease Questionnaire (SIBDQ), the Harvey-Bradshaw Index (HBI) for CD, and the Walmsley Index for UC (SCCAI) were collected. Results: A total of 2,841 patients aged over 18 were recruited (1785 with CD, 1056 with UC). The mean age was 40.2 (SD 14.3). The time since diagnosis was 6 years and over for 61.9% of patients. The most impacted dimensions were usual activities, anxiety/ depression, and pain/ discomfort. The mean utility value was 0.863 (SD 0.172) versus 0.905 (SD 0.158) in the French population (p = 0.007). The mean VAS value was 68 (SD 19.2) versus 73.4 (SD 22.2) in the general population (p = 0.016). Utility values and VAS were similar for CD and UC and higher for men. There was a strong positive correlation between utility values, the VAS, and the SIBDQ score, and a negative correlation between the HBI and the SCCAI. The SIBDQ score and disease activity were the main predictors of utility and VAS. Conclusion: The QALY-MICI is, to our knowledge, the first study documenting utility values and VAS using the EQ-5D-5 L questionnaire on a large sample, with a comparison to the general population. Plain English summary: Cost-effectiveness analyses have become an important component of assessing new health technologies. They require robust evidence to measure Quality of Life Adjusted Life Year gains. The Euroqol EQ-5D questionnaire is the main standard. Data on its use in inflammatory bowel disease (IBD) with its latest version, EQ-5D-5L, are limited to small samples. This study aimed at estimating utility values for IBD patients on a large sample in France, analysing the relationship between specific IBD quality of life and disease activity indexes, and identifying the main factors impacting patients' quality of life. A prospective, cross-sectional survey was designed amongst French IBD patients aged 18 and over from three sources (n=2,841). Utility values for IBD patients were lower than those observed in the French general population across all age groups. Men declared higher values than women. There was no difference between patients with Crohn's disease and those with ulcerative colitis. Patients with a quiescent disease had similar values to those of the general population. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 183284825
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Sarter%2C+H%2E%22">Sarter, H.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kirschgesner%2C+J%2E%22">Kirschgesner, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Beaugerie%2C+L%2E%22">Beaugerie, L.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Buisson%2C+A%2E%22">Buisson, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gower-Rousseau%2C+C%2E%22">Gower-Rousseau, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Pouvourville%2C+Gérard%22">de Pouvourville, Gérard</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Quality+of+Life+Research%22">Quality of Life Research</searchLink>. Feb2025, Vol. 34 Issue 2, p405-416. 12p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Inflammatory+bowel+diseases%22">Inflammatory bowel diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Visual+analog+scale%22">Visual analog scale</searchLink><br /><searchLink fieldCode="DE" term="%22Ulcerative+colitis%22">Ulcerative colitis</searchLink><br /><searchLink fieldCode="DE" term="%22Crohn's+disease%22">Crohn's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+reported+outcome+measures%22">Patient reported outcome measures</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22France%22">France</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Methods: QALY-MICI was a cross-sectional survey across three sources in France. Data were collected between 2019 and 2022 for patients 18 and over. The EQ-5D-5 L, the EQ-VAS, the Short Inflammatory Bowel Disease Questionnaire (SIBDQ), the Harvey-Bradshaw Index (HBI) for CD, and the Walmsley Index for UC (SCCAI) were collected. Results: A total of 2,841 patients aged over 18 were recruited (1785 with CD, 1056 with UC). The mean age was 40.2 (SD 14.3). The time since diagnosis was 6 years and over for 61.9% of patients. The most impacted dimensions were usual activities, anxiety/ depression, and pain/ discomfort. The mean utility value was 0.863 (SD 0.172) versus 0.905 (SD 0.158) in the French population (p = 0.007). The mean VAS value was 68 (SD 19.2) versus 73.4 (SD 22.2) in the general population (p = 0.016). Utility values and VAS were similar for CD and UC and higher for men. There was a strong positive correlation between utility values, the VAS, and the SIBDQ score, and a negative correlation between the HBI and the SCCAI. The SIBDQ score and disease activity were the main predictors of utility and VAS. Conclusion: The QALY-MICI is, to our knowledge, the first study documenting utility values and VAS using the EQ-5D-5 L questionnaire on a large sample, with a comparison to the general population. Plain English summary: Cost-effectiveness analyses have become an important component of assessing new health technologies. They require robust evidence to measure Quality of Life Adjusted Life Year gains. The Euroqol EQ-5D questionnaire is the main standard. Data on its use in inflammatory bowel disease (IBD) with its latest version, EQ-5D-5L, are limited to small samples. This study aimed at estimating utility values for IBD patients on a large sample in France, analysing the relationship between specific IBD quality of life and disease activity indexes, and identifying the main factors impacting patients' quality of life. A prospective, cross-sectional survey was designed amongst French IBD patients aged 18 and over from three sources (n=2,841). Utility values for IBD patients were lower than those observed in the French general population across all age groups. Men declared higher values than women. There was no difference between patients with Crohn's disease and those with ulcerative colitis. Patients with a quiescent disease had similar values to those of the general population. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=183284825
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s11136-024-03821-x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 405
    Subjects:
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Inflammatory bowel diseases
        Type: general
      – SubjectFull: Visual analog scale
        Type: general
      – SubjectFull: Ulcerative colitis
        Type: general
      – SubjectFull: Crohn's disease
        Type: general
      – SubjectFull: Patient reported outcome measures
        Type: general
      – SubjectFull: France
        Type: general
    Titles:
      – TitleFull: Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sarter, H.
      – PersonEntity:
          Name:
            NameFull: Kirschgesner, J.
      – PersonEntity:
          Name:
            NameFull: Beaugerie, L.
      – PersonEntity:
          Name:
            NameFull: Buisson, A.
      – PersonEntity:
          Name:
            NameFull: Gower-Rousseau, C.
      – PersonEntity:
          Name:
            NameFull: de Pouvourville, Gérard
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 09629343
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Quality of Life Research
              Type: main
ResultId 1