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Health-related quality of life due to malaria: a systematic review.

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Title: Health-related quality of life due to malaria: a systematic review.
Authors: Andrade, Mônica Viegas (AUTHOR), Noronha, Kenya (AUTHOR), Guedes, Gilvan Ramalho (AUTHOR), Diniz, Bernardo Campolina (AUTHOR), Silva, Valéria Andrade (AUTHOR), de Souza, Aline (AUTHOR), de Carvalho, Lucas Resende (AUTHOR), Braga, Paulo Estevão (AUTHOR), Motta-Santos, André Soares (AUTHOR), Julião, Nayara Abreu (AUTHOR), da Silva, Daniel Nogueira (AUTHOR), Bracarense, Henrique (AUTHOR), Castro, Marcia C. (AUTHOR)
Source: Quality of Life Research. Feb2025, Vol. 34 Issue 2, p325-339. 15p.
Subjects: Quality of life, Malaria, Socioeconomic disparities in health, Quality-adjusted life years, Health outcome assessment, Disease prevalence
Abstract: Purpose: This paper aims to conduct a systematic review (SR) to assess Health-Related Quality of Life (HRQoL) of malaria-exposed populations for different regions where malaria is endemic, considering any health measurements. Methods: An electronic search of the Medline, Lilacs, and Embase databases was conducted until February 2nd, 2024, to identify and select studies that evaluated HRQoL. No restrictions on place or language were made. Results: Thirty-seven studies were included, among them 21 focused on African countries. The most investigated HRQoL outcome associated with malaria was Disability-Adjusted Life Years (DALYs). These studies primarily aim to analyze the epidemiological burden of the disease or to conduct economic assessments. Only four studies conducted field research using specific instruments to assess the HRQoL of individuals experiencing malaria episodes. Three of them estimated EQ-5D utility index and found scores varying from 0.349 for severe malaria (Indonesia) to 0.74 (Nigeria). The health domains that are most affected by malaria are pain and discomfort and usual activities (EQ-5D instrument) and physical domains (WHOQOL-BREF). These results reflect the main malaria symptoms which are fever, headache, and generalized pain. Conclusion: This SR highlights a significant gap in understanding the quality of life among individuals experiencing malaria. Despite being an acute illness, recurrent episodes of malaria can lead to considerable loss in quality of life. Moreover, there are significant equity implications, as malaria remains endemic in socioeconomically disadvantaged populations. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Health-related quality of life due to malaria: a systematic review.
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  Data: <searchLink fieldCode="AR" term="%22Andrade%2C+Mônica+Viegas%22">Andrade, Mônica Viegas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Noronha%2C+Kenya%22">Noronha, Kenya</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guedes%2C+Gilvan+Ramalho%22">Guedes, Gilvan Ramalho</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Diniz%2C+Bernardo+Campolina%22">Diniz, Bernardo Campolina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Silva%2C+Valéria+Andrade%22">Silva, Valéria Andrade</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Souza%2C+Aline%22">de Souza, Aline</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Carvalho%2C+Lucas+Resende%22">de Carvalho, Lucas Resende</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Braga%2C+Paulo+Estevão%22">Braga, Paulo Estevão</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Motta-Santos%2C+André+Soares%22">Motta-Santos, André Soares</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Julião%2C+Nayara+Abreu%22">Julião, Nayara Abreu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22da+Silva%2C+Daniel+Nogueira%22">da Silva, Daniel Nogueira</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bracarense%2C+Henrique%22">Bracarense, Henrique</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Castro%2C+Marcia+C%2E%22">Castro, Marcia C.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Malaria%22">Malaria</searchLink><br /><searchLink fieldCode="DE" term="%22Socioeconomic+disparities+in+health%22">Socioeconomic disparities in health</searchLink><br /><searchLink fieldCode="DE" term="%22Quality-adjusted+life+years%22">Quality-adjusted life years</searchLink><br /><searchLink fieldCode="DE" term="%22Health+outcome+assessment%22">Health outcome assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink>
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  Data: Purpose: This paper aims to conduct a systematic review (SR) to assess Health-Related Quality of Life (HRQoL) of malaria-exposed populations for different regions where malaria is endemic, considering any health measurements. Methods: An electronic search of the Medline, Lilacs, and Embase databases was conducted until February 2nd, 2024, to identify and select studies that evaluated HRQoL. No restrictions on place or language were made. Results: Thirty-seven studies were included, among them 21 focused on African countries. The most investigated HRQoL outcome associated with malaria was Disability-Adjusted Life Years (DALYs). These studies primarily aim to analyze the epidemiological burden of the disease or to conduct economic assessments. Only four studies conducted field research using specific instruments to assess the HRQoL of individuals experiencing malaria episodes. Three of them estimated EQ-5D utility index and found scores varying from 0.349 for severe malaria (Indonesia) to 0.74 (Nigeria). The health domains that are most affected by malaria are pain and discomfort and usual activities (EQ-5D instrument) and physical domains (WHOQOL-BREF). These results reflect the main malaria symptoms which are fever, headache, and generalized pain. Conclusion: This SR highlights a significant gap in understanding the quality of life among individuals experiencing malaria. Despite being an acute illness, recurrent episodes of malaria can lead to considerable loss in quality of life. Moreover, there are significant equity implications, as malaria remains endemic in socioeconomically disadvantaged populations. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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