View in EDS HTML Full Text PDF Full Text

Lateralization‐specific adaptation in auditory cortical evoked potentials: Comparison with frequency‐specificity.

Saved in:
Bibliographic Details
Title: Lateralization‐specific adaptation in auditory cortical evoked potentials: Comparison with frequency‐specificity.
Authors: İlhan, Barkın (AUTHOR), Kurt, Saliha (AUTHOR), Bolay, Yavuz (AUTHOR), Ungan, Pekcan (AUTHOR)
Source: European Journal of Neuroscience. Jan2025, Vol. 61 Issue 1, p1-19. 19p.
Subjects: Interaural time difference, Auditory evoked response, Lateral dominance, Habituation (Neuropsychology), Neurons, Frequency response, Acoustic localization
Abstract: 'Opponent channels model' (OCM) is the widely accepted model for cortical representation of sound lateralization. Stimulus‐specific 'release from adaptation' (RFA) in cortical responses has been used in previous studies to test the predictions of this model. However, these attempts were shown to be prone to confounds of spurious responses such as those to auditory motion and sound onset. The present study aims to determine whether a multiple‐adaptor RFA algorithm could be employed for relatively confound‐free quantification of the population response of lateralization‐specific auditory cortical neurons, and provide useful data for estimation of the OCM hemifield tuning curves. Two experiments were conducted on 12 volunteers with normal hearing. In Exp.1, quadruple tone pips of either low or high frequency were presented as adaptor, followed by a single tone pip of either frequency as probe. In Exp.2, tone pips were replaced with dichotic click train pips with left‐leading and right‐leading interaural time difference (ITD). Frequency‐ and ITD‐specific RFA in cortical responses N1 and P2 was quantified using global field magnitude difference between ERPs to mismatched and matched adaptor‐probe pairs. RFA level measured was lower for ITD mismatch than frequency mismatch. Nonetheless, it allowed measurement of ITD‐specific cortical neurons' population response, without any spurious response confound. We proposed a method for extraction of ITD‐specific response magnitude from the N1 response to a lateralized sound. Using it, one can reliably measure the activity of lateralization‐specific cortical neurons, i.e. elicited by moderate ITD changes. This allows estimation of hemifield tuning curves in OCM using ERP data. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 184019496
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lateralization‐specific adaptation in auditory cortical evoked potentials: Comparison with frequency‐specificity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22İlhan%2C+Barkın%22">İlhan, Barkın</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kurt%2C+Saliha%22">Kurt, Saliha</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bolay%2C+Yavuz%22">Bolay, Yavuz</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ungan%2C+Pekcan%22">Ungan, Pekcan</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neuroscience%22">European Journal of Neuroscience</searchLink>. Jan2025, Vol. 61 Issue 1, p1-19. 19p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Interaural+time+difference%22">Interaural time difference</searchLink><br /><searchLink fieldCode="DE" term="%22Auditory+evoked+response%22">Auditory evoked response</searchLink><br /><searchLink fieldCode="DE" term="%22Lateral+dominance%22">Lateral dominance</searchLink><br /><searchLink fieldCode="DE" term="%22Habituation+%28Neuropsychology%29%22">Habituation (Neuropsychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Neurons%22">Neurons</searchLink><br /><searchLink fieldCode="DE" term="%22Frequency+response%22">Frequency response</searchLink><br /><searchLink fieldCode="DE" term="%22Acoustic+localization%22">Acoustic localization</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: 'Opponent channels model' (OCM) is the widely accepted model for cortical representation of sound lateralization. Stimulus‐specific 'release from adaptation' (RFA) in cortical responses has been used in previous studies to test the predictions of this model. However, these attempts were shown to be prone to confounds of spurious responses such as those to auditory motion and sound onset. The present study aims to determine whether a multiple‐adaptor RFA algorithm could be employed for relatively confound‐free quantification of the population response of lateralization‐specific auditory cortical neurons, and provide useful data for estimation of the OCM hemifield tuning curves. Two experiments were conducted on 12 volunteers with normal hearing. In Exp.1, quadruple tone pips of either low or high frequency were presented as adaptor, followed by a single tone pip of either frequency as probe. In Exp.2, tone pips were replaced with dichotic click train pips with left‐leading and right‐leading interaural time difference (ITD). Frequency‐ and ITD‐specific RFA in cortical responses N1 and P2 was quantified using global field magnitude difference between ERPs to mismatched and matched adaptor‐probe pairs. RFA level measured was lower for ITD mismatch than frequency mismatch. Nonetheless, it allowed measurement of ITD‐specific cortical neurons' population response, without any spurious response confound. We proposed a method for extraction of ITD‐specific response magnitude from the N1 response to a lateralized sound. Using it, one can reliably measure the activity of lateralization‐specific cortical neurons, i.e. elicited by moderate ITD changes. This allows estimation of hemifield tuning curves in OCM using ERP data. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=184019496
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/ejn.16644
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 19
        StartPage: 1
    Subjects:
      – SubjectFull: Interaural time difference
        Type: general
      – SubjectFull: Auditory evoked response
        Type: general
      – SubjectFull: Lateral dominance
        Type: general
      – SubjectFull: Habituation (Neuropsychology)
        Type: general
      – SubjectFull: Neurons
        Type: general
      – SubjectFull: Frequency response
        Type: general
      – SubjectFull: Acoustic localization
        Type: general
    Titles:
      – TitleFull: Lateralization‐specific adaptation in auditory cortical evoked potentials: Comparison with frequency‐specificity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: İlhan, Barkın
      – PersonEntity:
          Name:
            NameFull: Kurt, Saliha
      – PersonEntity:
          Name:
            NameFull: Bolay, Yavuz
      – PersonEntity:
          Name:
            NameFull: Ungan, Pekcan
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 0953816X
          Numbering:
            – Type: volume
              Value: 61
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: European Journal of Neuroscience
              Type: main
ResultId 1