View in EDS HTML Full Text PDF Full Text

Nocturnal Hypoxemia and Daytime Sleepiness in Epilepsy With Obstructive Sleep Apnea‐Hypopnea Syndrome: A Case–Control Polysomnography Study.

Saved in:
Bibliographic Details
Title: Nocturnal Hypoxemia and Daytime Sleepiness in Epilepsy With Obstructive Sleep Apnea‐Hypopnea Syndrome: A Case–Control Polysomnography Study.
Authors: Wu, Meina (AUTHOR), Wu, Sangru (AUTHOR), Wang, Sihang (AUTHOR), Lin, Fang (AUTHOR), Ji, Xiaolin (AUTHOR), Yan, Jinzhu (AUTHOR), Colosimo, Carlo (AUTHOR)
Source: Acta Neurologica Scandinavica. 4/22/2025, Vol. 2025, p1-13. 13p.
Subjects: Sleep disorders, Epilepsy, Hypoxemia, Sleep apnea syndromes, Drowsiness, Polysomnography
Abstract: Sleep disorders are common in patients with epilepsy, affecting their quality of life. In this study, we aimed to explore the sleep structure of adult patients with epilepsy and determine its correlation with different degrees of obstructive sleep apnea‐hypopnea syndrome (OSAHS). We also examined the impact of intermittent hypoxemia on nocturnal sleep structure, respiratory‐related events, and excessive daytime sleepiness (EDS). This case–control polysomnography study included 81 patients with epilepsy and 86 healthy controls. Polysomnography combined with video electroencephalography was used to assess sleep structure, respiratory‐related events, and factors related to EDS. Patients with epilepsy had a higher prevalence of sleep disorders, hypoxemia, and EDS than controls. Comorbid moderate‐to‐severe OSAHS was associated with increased risk of severe hypoxemia and awakening. Intermittent and mean hypoxemia worsened with increasing apnea‐hypopnea index. The incidence of EDS increased drastically in patients with comorbid moderate‐to‐severe OSAHS. The total sleep period time was a significant independent predictor of the occurrence of EDS in patients with comorbid moderate‐to‐severe OSAHS. The study findings indicate that patients with epilepsy experience changes in sleep structure, and the coexistence of OSAHS increases the risk of hypoxemia and EDS. These findings are useful in clinical prognostication of patients with epilepsy comorbid with OSAHS. [ABSTRACT FROM AUTHOR]
Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 184680101
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Nocturnal Hypoxemia and Daytime Sleepiness in Epilepsy With Obstructive Sleep Apnea‐Hypopnea Syndrome: A Case–Control Polysomnography Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Wu%2C+Meina%22">Wu, Meina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Sangru%22">Wu, Sangru</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Sihang%22">Wang, Sihang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lin%2C+Fang%22">Lin, Fang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ji%2C+Xiaolin%22">Ji, Xiaolin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yan%2C+Jinzhu%22">Yan, Jinzhu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Colosimo%2C+Carlo%22">Colosimo, Carlo</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. 4/22/2025, Vol. 2025, p1-13. 13p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Sleep+disorders%22">Sleep disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Epilepsy%22">Epilepsy</searchLink><br /><searchLink fieldCode="DE" term="%22Hypoxemia%22">Hypoxemia</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep+apnea+syndromes%22">Sleep apnea syndromes</searchLink><br /><searchLink fieldCode="DE" term="%22Drowsiness%22">Drowsiness</searchLink><br /><searchLink fieldCode="DE" term="%22Polysomnography%22">Polysomnography</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Sleep disorders are common in patients with epilepsy, affecting their quality of life. In this study, we aimed to explore the sleep structure of adult patients with epilepsy and determine its correlation with different degrees of obstructive sleep apnea‐hypopnea syndrome (OSAHS). We also examined the impact of intermittent hypoxemia on nocturnal sleep structure, respiratory‐related events, and excessive daytime sleepiness (EDS). This case–control polysomnography study included 81 patients with epilepsy and 86 healthy controls. Polysomnography combined with video electroencephalography was used to assess sleep structure, respiratory‐related events, and factors related to EDS. Patients with epilepsy had a higher prevalence of sleep disorders, hypoxemia, and EDS than controls. Comorbid moderate‐to‐severe OSAHS was associated with increased risk of severe hypoxemia and awakening. Intermittent and mean hypoxemia worsened with increasing apnea‐hypopnea index. The incidence of EDS increased drastically in patients with comorbid moderate‐to‐severe OSAHS. The total sleep period time was a significant independent predictor of the occurrence of EDS in patients with comorbid moderate‐to‐severe OSAHS. The study findings indicate that patients with epilepsy experience changes in sleep structure, and the coexistence of OSAHS increases the risk of hypoxemia and EDS. These findings are useful in clinical prognostication of patients with epilepsy comorbid with OSAHS. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=184680101
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1155/ane/6336114
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 1
    Subjects:
      – SubjectFull: Sleep disorders
        Type: general
      – SubjectFull: Epilepsy
        Type: general
      – SubjectFull: Hypoxemia
        Type: general
      – SubjectFull: Sleep apnea syndromes
        Type: general
      – SubjectFull: Drowsiness
        Type: general
      – SubjectFull: Polysomnography
        Type: general
    Titles:
      – TitleFull: Nocturnal Hypoxemia and Daytime Sleepiness in Epilepsy With Obstructive Sleep Apnea‐Hypopnea Syndrome: A Case–Control Polysomnography Study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wu, Meina
      – PersonEntity:
          Name:
            NameFull: Wu, Sangru
      – PersonEntity:
          Name:
            NameFull: Wang, Sihang
      – PersonEntity:
          Name:
            NameFull: Lin, Fang
      – PersonEntity:
          Name:
            NameFull: Ji, Xiaolin
      – PersonEntity:
          Name:
            NameFull: Yan, Jinzhu
      – PersonEntity:
          Name:
            NameFull: Colosimo, Carlo
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 22
              M: 04
              Text: 4/22/2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 00016314
          Numbering:
            – Type: volume
              Value: 2025
          Titles:
            – TitleFull: Acta Neurologica Scandinavica
              Type: main
ResultId 1