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Gene programs driving cortical neuron specifications.

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Title: Gene programs driving cortical neuron specifications.
Authors: He, Zhisong (AUTHOR), Treutlein, Barbara (AUTHOR)
Source: Nature Neuroscience. May2025, Vol. 28 Issue 5, p919-920. 2p.
Abstract: The cerebral cortex of the human brain is crucial and complex, and includes different subtypes of neuron that need to be specified during development. How this process is regulated is unclear. In this issue of Nature Neuroscience, Nano et al. curate and mine a compendium cell atlas of human cortical development to identify gene programs that drive neuron subtype specification and validate a mechanism using brain organoid models. [ABSTRACT FROM AUTHOR]
Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Gene programs driving cortical neuron specifications.
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  Data: <searchLink fieldCode="AR" term="%22He%2C+Zhisong%22">He, Zhisong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Treutlein%2C+Barbara%22">Treutlein, Barbara</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Nature+Neuroscience%22">Nature Neuroscience</searchLink>. May2025, Vol. 28 Issue 5, p919-920. 2p.
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  Label: Abstract
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  Data: The cerebral cortex of the human brain is crucial and complex, and includes different subtypes of neuron that need to be specified during development. How this process is regulated is unclear. In this issue of Nature Neuroscience, Nano et al. curate and mine a compendium cell atlas of human cortical development to identify gene programs that drive neuron subtype specification and validate a mechanism using brain organoid models. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1038/s41593-025-01934-1
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              Text: May2025
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              Y: 2025
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