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Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study.

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Title: Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study.
Authors: Marra, Camillo (AUTHOR), Beccia, Flavia (AUTHOR), Caffarra, Paolo (AUTHOR), L'Abbate, Federica (AUTHOR), Agosta, Federica (AUTHOR), Benussi, Alberto (AUTHOR), Bonanni, Laura (AUTHOR), Bruni, Amalia C. (AUTHOR), Bruno, Giuseppe (AUTHOR), Cappa, Stefano F. (AUTHOR), Cerami, Chiara (AUTHOR), Di Lorenzo, Francesco (AUTHOR), Ferrarese, Carlo (AUTHOR), Galimberti, Daniela (AUTHOR), Guarnieri, Biancamaria (AUTHOR), Mariani, Claudio (AUTHOR), Nacmias, Benedetta (AUTHOR), Pantoni, Leonardo (AUTHOR), Piccoli, Tommaso (AUTHOR), Perani, Daniela (AUTHOR)
Source: Neurological Sciences. Jul2025, Vol. 46 Issue 7, p2913-2923. 11p.
Subjects: Alzheimer's disease, Delphi method, Cognition disorders, Value-based management, Dementia
Geographic Terms: Italy
Abstract: This national expert-based Delphi-consensus aims at formulating recommendations on the management of dementia care in Italy. This effort seems important and timely given in light of a new scenario arising from a new biological definition of Alzheimer's disease (AD) and the availability of disease-modifying treatments (DMTs). Methods: the Steering Committee of the Italian Neurological Society for dementia (SINdem) created appropriate statements. Invited SINdem experts were requested to vote on the statements according to a modified three-round Delphi method. Only those statements reaching Grade A (full agreement ≥ 75%) or B (overall agreement ≥ 80% and full disagreement < 5%) were included in the final document. Round answers' consistency was graded using the Cohen's k and within-class correlation coefficient. Results: Forty-six experts voted on 20 statements, which focused on the following aspects: i) organization of care services from early diagnosis to the management of advanced clinical stages; ii) access to biomarkers for a biological diagnosis of AD; iii) requirements necessary for the administration of DMTs; iv) main actors and pathways for the management of patients suffering from cognitive disorders. At the end of the process, 4 statements (20%) received a Grade A consensus, while 16 (80%) reached a Grade B consensus. Although the responses reflect heterogeneity among Italian regions, there was a fair degree of consistency for all statements. Conclusion: The high strength of this expert-based Delphi-consensus may offer guidance for improving the patient's journey of individuals with cognitive decline from a biological diagnosis to DMTs administration and may possibly offer hints to the Health Systems on dementia. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study.
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  Data: This national expert-based Delphi-consensus aims at formulating recommendations on the management of dementia care in Italy. This effort seems important and timely given in light of a new scenario arising from a new biological definition of Alzheimer&#39;s disease (AD) and the availability of disease-modifying treatments (DMTs). Methods: the Steering Committee of the Italian Neurological Society for dementia (SINdem) created appropriate statements. Invited SINdem experts were requested to vote on the statements according to a modified three-round Delphi method. Only those statements reaching Grade A (full agreement ≥ 75%) or B (overall agreement ≥ 80% and full disagreement &lt; 5%) were included in the final document. Round answers&#39; consistency was graded using the Cohen&#39;s k and within-class correlation coefficient. Results: Forty-six experts voted on 20 statements, which focused on the following aspects: i) organization of care services from early diagnosis to the management of advanced clinical stages; ii) access to biomarkers for a biological diagnosis of AD; iii) requirements necessary for the administration of DMTs; iv) main actors and pathways for the management of patients suffering from cognitive disorders. At the end of the process, 4 statements (20%) received a Grade A consensus, while 16 (80%) reached a Grade B consensus. Although the responses reflect heterogeneity among Italian regions, there was a fair degree of consistency for all statements. Conclusion: The high strength of this expert-based Delphi-consensus may offer guidance for improving the patient&#39;s journey of individuals with cognitive decline from a biological diagnosis to DMTs administration and may possibly offer hints to the Health Systems on dementia. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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