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Supraglottoplasty and thriving in laryngomalacia. Is there a nexus?

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Title: Supraglottoplasty and thriving in laryngomalacia. Is there a nexus?
Authors: Silva Sousa, Patrícia (AUTHOR), Coutinho, Gil (AUTHOR), Andrade, António (AUTHOR), Vaz, Ricardo (AUTHOR), Pinto Moura, Carla (AUTHOR), Spratley, Jorge (AUTHOR)
Source: Acta Oto-Laryngologica. Jun2025, Vol. 145 Issue 6, p536-539. 4p.
Subjects: Laryngomalacia, World Health Organization, Academic medical centers, Scientific observation, Body weight, Severity of illness index, Treatment effectiveness, Respiratory diseases, Tertiary care, Descriptive statistics, Mann Whitney U Test, Human growth, Longitudinal method, Laryngoscopy, Eating disorders, Sleep apnea syndromes, Data analysis software, Polysomnography, Glottis, Weight gain, Comorbidity, Gastroesophageal reflux, Cyanosis, Evaluation, Symptoms
Abstract (English): Background: Feeding difficulties and failure to thrive are common findings in severe laryngomalacia. Aims: To evaluate the outcomes of supraglottoplasty for severe laryngomalacia and its impact on weight progression. Material and methods: Observational cohort study of paediatric patients with laryngomalacia who underwent supraglottoplasty from 2018 to 2023. Postoperative outcomes, including weight, were evaluated. Children with comorbidities affecting growth were excluded. Results: Thirty-eight children with severe laryngomalacia underwent supraglottoplasty, with 32 meeting the inclusion criteria; 59.4% were male. The mean age at diagnosis and surgery was 5.8 and 10.5 months, respectively. All cases of respiratory distress were resolved with surgery. In the weight evaluation, 18 patients (56.3%) had a preoperative percentile below 15, of whom ten were below the 5th percentile. A statistically significant increase was observed between preoperative percentile and consecutive postoperative percentiles at 1, 3 and 12 months. Regarding children with percentile below 15, 75% successfully crossed two percentile lines and 90% of children with failure to thrive managed to rise above the 5th percentile. Conclusions and significance: Supraglottoplasty leads to symptomatic improvement and a significant increase in weight percentile in patients with severe laryngomalacia. Growth curves adjusted for gender and age should be an objective measure of supraglottoplasty outcomes. [ABSTRACT FROM AUTHOR]
Abstract (Chinese): 喂养困难和发育迟缓是重度喉软骨软化症的常见特征。 评估声门上成形术治疗重度喉软骨软化症的疗效及其对体重增长的影响。 本研究是一项观察性队列研究, 纳入了2018年至2023年接受声门上成形术的儿童喉软骨软化症患者。评估了术后疗效, 包括体重。患有影响生长发育的合并症的儿童被排除在外。 38例重度喉软骨软化症儿童接受了声门上成形术, 其中32例符合纳入标准；59.4%为男性。确诊时和手术时的平均年龄分别为5.8个月和10.5个月。所有呼吸窘迫病例均通过手术得到缓解。体重评估中, 18例(56.3%)患者术前百分位数低于15, 10例低于5。术前百分位数与术后1、3和12个月时的连续百分位数之间均有显著差异。对于百分位数低于15的患儿, 75%成功跨越两个百分位数线, 90%的发育不良患儿提升5个百分位数以上。 对于重度喉软化症患者, 声门上成形术可改善症状并显著提高体重百分位数。根据性别和年龄调整的生长曲线应是衡量声门上成形术疗效的客观指标。 [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
  Group: Ti
  Data: Supraglottoplasty and thriving in laryngomalacia. Is there a nexus?
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  Data: <searchLink fieldCode="AR" term="%22Silva+Sousa%2C+Patrícia%22">Silva Sousa, Patrícia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Coutinho%2C+Gil%22">Coutinho, Gil</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Andrade%2C+António%22">Andrade, António</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vaz%2C+Ricardo%22">Vaz, Ricardo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pinto+Moura%2C+Carla%22">Pinto Moura, Carla</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Spratley%2C+Jorge%22">Spratley, Jorge</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Jun2025, Vol. 145 Issue 6, p536-539. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Laryngomalacia%22">Laryngomalacia</searchLink><br /><searchLink fieldCode="DE" term="%22World+Health+Organization%22">World Health Organization</searchLink><br /><searchLink fieldCode="DE" term="%22Academic+medical+centers%22">Academic medical centers</searchLink><br /><searchLink fieldCode="DE" term="%22Scientific+observation%22">Scientific observation</searchLink><br /><searchLink fieldCode="DE" term="%22Body+weight%22">Body weight</searchLink><br /><searchLink fieldCode="DE" term="%22Severity+of+illness+index%22">Severity of illness index</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Respiratory+diseases%22">Respiratory diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Tertiary+care%22">Tertiary care</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Mann+Whitney+U+Test%22">Mann Whitney U Test</searchLink><br /><searchLink fieldCode="DE" term="%22Human+growth%22">Human growth</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Laryngoscopy%22">Laryngoscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Eating+disorders%22">Eating disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep+apnea+syndromes%22">Sleep apnea syndromes</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Polysomnography%22">Polysomnography</searchLink><br /><searchLink fieldCode="DE" term="%22Glottis%22">Glottis</searchLink><br /><searchLink fieldCode="DE" term="%22Weight+gain%22">Weight gain</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Gastroesophageal+reflux%22">Gastroesophageal reflux</searchLink><br /><searchLink fieldCode="DE" term="%22Cyanosis%22">Cyanosis</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation%22">Evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms%22">Symptoms</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Background: Feeding difficulties and failure to thrive are common findings in severe laryngomalacia. Aims: To evaluate the outcomes of supraglottoplasty for severe laryngomalacia and its impact on weight progression. Material and methods: Observational cohort study of paediatric patients with laryngomalacia who underwent supraglottoplasty from 2018 to 2023. Postoperative outcomes, including weight, were evaluated. Children with comorbidities affecting growth were excluded. Results: Thirty-eight children with severe laryngomalacia underwent supraglottoplasty, with 32 meeting the inclusion criteria; 59.4% were male. The mean age at diagnosis and surgery was 5.8 and 10.5 months, respectively. All cases of respiratory distress were resolved with surgery. In the weight evaluation, 18 patients (56.3%) had a preoperative percentile below 15, of whom ten were below the 5th percentile. A statistically significant increase was observed between preoperative percentile and consecutive postoperative percentiles at 1, 3 and 12 months. Regarding children with percentile below 15, 75% successfully crossed two percentile lines and 90% of children with failure to thrive managed to rise above the 5th percentile. Conclusions and significance: Supraglottoplasty leads to symptomatic improvement and a significant increase in weight percentile in patients with severe laryngomalacia. Growth curves adjusted for gender and age should be an objective measure of supraglottoplasty outcomes. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Chinese)
  Group: Ab
  Data: 喂养困难和发育迟缓是重度喉软骨软化症的常见特征。 评估声门上成形术治疗重度喉软骨软化症的疗效及其对体重增长的影响。 本研究是一项观察性队列研究, 纳入了2018年至2023年接受声门上成形术的儿童喉软骨软化症患者。评估了术后疗效, 包括体重。患有影响生长发育的合并症的儿童被排除在外。 38例重度喉软骨软化症儿童接受了声门上成形术, 其中32例符合纳入标准；59.4%为男性。确诊时和手术时的平均年龄分别为5.8个月和10.5个月。所有呼吸窘迫病例均通过手术得到缓解。体重评估中, 18例(56.3%)患者术前百分位数低于15, 10例低于5。术前百分位数与术后1、3和12个月时的连续百分位数之间均有显著差异。对于百分位数低于15的患儿, 75%成功跨越两个百分位数线, 90%的发育不良患儿提升5个百分位数以上。 对于重度喉软化症患者, 声门上成形术可改善症状并显著提高体重百分位数。根据性别和年龄调整的生长曲线应是衡量声门上成形术疗效的客观指标。 [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/00016489.2025.2488487
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 4
        StartPage: 536
    Subjects:
      – SubjectFull: Laryngomalacia
        Type: general
      – SubjectFull: World Health Organization
        Type: general
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: Scientific observation
        Type: general
      – SubjectFull: Body weight
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      – SubjectFull: Severity of illness index
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      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Respiratory diseases
        Type: general
      – SubjectFull: Tertiary care
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Mann Whitney U Test
        Type: general
      – SubjectFull: Human growth
        Type: general
      – SubjectFull: Longitudinal method
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      – SubjectFull: Laryngoscopy
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      – SubjectFull: Eating disorders
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      – SubjectFull: Symptoms
        Type: general
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      – TitleFull: Supraglottoplasty and thriving in laryngomalacia. Is there a nexus?
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              Text: Jun2025
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