Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.

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Title: Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.
Authors: Narváez‐Camargo, Marta (AUTHOR), Lozano‐Rojas, Oscar (AUTHOR), Mancheño‐Velasco, Cinta (AUTHOR), Verdejo‐García, Antonio (AUTHOR)
Source: International Journal of Methods in Psychiatric Research. Jun2025, Vol. 34 Issue 2, p1-27. 27p.
Subjects: Treatment effectiveness, Standardization, Well-being, Statistics, Substance-induced disorders, Standards
Abstract: Aim: The heterogeneous metrics and criteria used to assess the effectiveness of substance use disorders treatment hinders cross‐study comparisons. This review aims to parse such heterogeneity by analysing the operational definitions of variables used to derive metrics and outcome criteria, contributing to the standardisation process. Methods: We conducted a systematic review in PubMed and PsycINFO between January 2000 and October 2023. We included published studies on substance use disorders that featured at least one of seven 'a priori' defined variables commonly used to obtain metrics and criteria for treatment effectiveness. The review process and reporting followed Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA) guidelines. Results: Were identified three areas that can be used to define metrics and criteria associated with treatment outcome: as 'substance use' (abstinence and relapses), 'treatment process' (readmission, dropout, retention, and adherence) and 'general wellbeing' (quality of life). Operational definitions and metrics and criteria used were overall inconsistent. Conclusions: The establishment of guidelines for evaluation of treatment outcomes is imperative, as heterogeneity is still present in the literature. We recommend that future trials provide outcomes metrics relevant to the identified categories, and that standardisation efforts continue toward harmonised criteria to report and interpret those metrics. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Methods in Psychiatric Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Group: Ti
  Data: Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Narváez‐Camargo%2C+Marta%22">Narváez‐Camargo, Marta</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lozano‐Rojas%2C+Oscar%22">Lozano‐Rojas, Oscar</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mancheño‐Velasco%2C+Cinta%22">Mancheño‐Velasco, Cinta</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Verdejo‐García%2C+Antonio%22">Verdejo‐García, Antonio</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Methods+in+Psychiatric+Research%22">International Journal of Methods in Psychiatric Research</searchLink>. Jun2025, Vol. 34 Issue 2, p1-27. 27p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Standardization%22">Standardization</searchLink><br /><searchLink fieldCode="DE" term="%22Well-being%22">Well-being</searchLink><br /><searchLink fieldCode="DE" term="%22Statistics%22">Statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Substance-induced+disorders%22">Substance-induced disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Standards%22">Standards</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Aim: The heterogeneous metrics and criteria used to assess the effectiveness of substance use disorders treatment hinders cross‐study comparisons. This review aims to parse such heterogeneity by analysing the operational definitions of variables used to derive metrics and outcome criteria, contributing to the standardisation process. Methods: We conducted a systematic review in PubMed and PsycINFO between January 2000 and October 2023. We included published studies on substance use disorders that featured at least one of seven 'a priori' defined variables commonly used to obtain metrics and criteria for treatment effectiveness. The review process and reporting followed Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA) guidelines. Results: Were identified three areas that can be used to define metrics and criteria associated with treatment outcome: as 'substance use' (abstinence and relapses), 'treatment process' (readmission, dropout, retention, and adherence) and 'general wellbeing' (quality of life). Operational definitions and metrics and criteria used were overall inconsistent. Conclusions: The establishment of guidelines for evaluation of treatment outcomes is imperative, as heterogeneity is still present in the literature. We recommend that future trials provide outcomes metrics relevant to the identified categories, and that standardisation efforts continue toward harmonised criteria to report and interpret those metrics. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of International Journal of Methods in Psychiatric Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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        Value: 10.1002/mpr.70027
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      – Code: eng
        Text: English
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        Type: general
      – SubjectFull: Standardization
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      – SubjectFull: Well-being
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Substance-induced disorders
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      – SubjectFull: Standards
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      – TitleFull: Substance Use Disorder Treatment Outcomes: Methodological Overview of Metrics and Criteria.
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            NameFull: Narváez‐Camargo, Marta
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            NameFull: Lozano‐Rojas, Oscar
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            NameFull: Mancheño‐Velasco, Cinta
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            NameFull: Verdejo‐García, Antonio
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            – D: 01
              M: 06
              Text: Jun2025
              Type: published
              Y: 2025
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