View in EDS HTML Full Text PDF Full Text

Burden of Parkinson's disease in Iran: disparities, trends, and the impact of social development indicators.

Saved in:
Bibliographic Details
Title: Burden of Parkinson's disease in Iran: disparities, trends, and the impact of social development indicators.
Authors: Sarmadi, Mohammad (AUTHOR), Rezaei, Mina (AUTHOR), Poursadeghiyan, Mohsen (AUTHOR), Soltaninejad, Mohammadreza (AUTHOR), Moradi, Sadegh (AUTHOR), Ahangarzadeh, Milad (AUTHOR), Mahdiabadi, Morteza Zaboli (AUTHOR), Rahimi, Sajjad (AUTHOR)
Source: Neurological Sciences. Aug2025, Vol. 46 Issue 8, p3651-3662. 12p.
Subjects: Human Development Index, Parkinson's disease, Global burden of disease, Medical sciences, Regression analysis
Abstract: Background: The burden of Parkinson's disease (PD) and its provincial trends in Iran remain unknown. Herein, we explore PD data from the Global Burden of Disease (GBD) study nationally and provincially from 1990 to 2021. Methods: We used age-standardized incidence (ASIR), prevalence (ASPR), and mortality (ASMR) rates to determine disparities and trends overall and by sex, age, and geographic locations. Univariate analysis and regression were performed to scrutinize the mean differences and associations between socioeconomic factors and different PD outcomes. Results: The ASIR and ASPR of PD increased by 23.1% and 33.2%, respectively, from 1990 to 2021, with estimated total percentage change (TPC) of 0.50 (95%CU: 0.58–0.43) and 0.30 (0.37–0.24), respectively. In 2021, East Azarbayejan had the highest ASIR and ASPR. From 1999 to 2021, the ASMR decreased significantly across individuals aged below 85 years nationally. Overall, 71.0% provinces experienced a downward trend in the ASMR, with the highest decrease in the TPC (-0.21,-0.37–0.01) occurring in Markazi. Significant differences in the PD outcomes between males and females were noted (P < 0.05). There was a significant positive association between the ASPR and the human development index (HDI), urbanization rate, and annual income per rural households. Conclusion: From 1999 to 2021, the incidence and prevalence of PD in Iran and its provinces increased significantly regardless of age and sex classification. Intervention and screening programs should continue to reduce mortality from PD in Iran, but with different priorities between provinces. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 186678267
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Burden of Parkinson&#39;s disease in Iran: disparities, trends, and the impact of social development indicators.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Sarmadi%2C+Mohammad%22&quot;&gt;Sarmadi, Mohammad&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rezaei%2C+Mina%22&quot;&gt;Rezaei, Mina&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Poursadeghiyan%2C+Mohsen%22&quot;&gt;Poursadeghiyan, Mohsen&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Soltaninejad%2C+Mohammadreza%22&quot;&gt;Soltaninejad, Mohammadreza&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Moradi%2C+Sadegh%22&quot;&gt;Moradi, Sadegh&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ahangarzadeh%2C+Milad%22&quot;&gt;Ahangarzadeh, Milad&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mahdiabadi%2C+Morteza+Zaboli%22&quot;&gt;Mahdiabadi, Morteza Zaboli&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rahimi%2C+Sajjad%22&quot;&gt;Rahimi, Sajjad&lt;/searchLink&gt; (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Neurological+Sciences%22&quot;&gt;Neurological Sciences&lt;/searchLink&gt;. Aug2025, Vol. 46 Issue 8, p3651-3662. 12p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Human+Development+Index%22&quot;&gt;Human Development Index&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Parkinson&#39;s+disease%22&quot;&gt;Parkinson&#39;s disease&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Global+burden+of+disease%22&quot;&gt;Global burden of disease&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Medical+sciences%22&quot;&gt;Medical sciences&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Regression+analysis%22&quot;&gt;Regression analysis&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: The burden of Parkinson&#39;s disease (PD) and its provincial trends in Iran remain unknown. Herein, we explore PD data from the Global Burden of Disease (GBD) study nationally and provincially from 1990 to 2021. Methods: We used age-standardized incidence (ASIR), prevalence (ASPR), and mortality (ASMR) rates to determine disparities and trends overall and by sex, age, and geographic locations. Univariate analysis and regression were performed to scrutinize the mean differences and associations between socioeconomic factors and different PD outcomes. Results: The ASIR and ASPR of PD increased by 23.1% and 33.2%, respectively, from 1990 to 2021, with estimated total percentage change (TPC) of 0.50 (95%CU: 0.58–0.43) and 0.30 (0.37–0.24), respectively. In 2021, East Azarbayejan had the highest ASIR and ASPR. From 1999 to 2021, the ASMR decreased significantly across individuals aged below 85 years nationally. Overall, 71.0% provinces experienced a downward trend in the ASMR, with the highest decrease in the TPC (-0.21,-0.37–0.01) occurring in Markazi. Significant differences in the PD outcomes between males and females were noted (P &lt; 0.05). There was a significant positive association between the ASPR and the human development index (HDI), urbanization rate, and annual income per rural households. Conclusion: From 1999 to 2021, the incidence and prevalence of PD in Iran and its provinces increased significantly regardless of age and sex classification. Intervention and screening programs should continue to reduce mortality from PD in Iran, but with different priorities between provinces. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=186678267
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10072-025-08206-7
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 3651
    Subjects:
      – SubjectFull: Human Development Index
        Type: general
      – SubjectFull: Parkinson's disease
        Type: general
      – SubjectFull: Global burden of disease
        Type: general
      – SubjectFull: Medical sciences
        Type: general
      – SubjectFull: Regression analysis
        Type: general
    Titles:
      – TitleFull: Burden of Parkinson's disease in Iran: disparities, trends, and the impact of social development indicators.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sarmadi, Mohammad
      – PersonEntity:
          Name:
            NameFull: Rezaei, Mina
      – PersonEntity:
          Name:
            NameFull: Poursadeghiyan, Mohsen
      – PersonEntity:
          Name:
            NameFull: Soltaninejad, Mohammadreza
      – PersonEntity:
          Name:
            NameFull: Moradi, Sadegh
      – PersonEntity:
          Name:
            NameFull: Ahangarzadeh, Milad
      – PersonEntity:
          Name:
            NameFull: Mahdiabadi, Morteza Zaboli
      – PersonEntity:
          Name:
            NameFull: Rahimi, Sajjad
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: Aug2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 15901874
          Numbering:
            – Type: volume
              Value: 46
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Neurological Sciences
              Type: main
ResultId 1