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Recognition and Management of Iatrogenically Induced Opioid Dependence and Withdrawal in Children: Clinical Report.

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Bibliographic Details
Title: Recognition and Management of Iatrogenically Induced Opioid Dependence and Withdrawal in Children: Clinical Report.
Authors: Adler, Adam C., Siegel, Linda B., Wilder, Robert T., Good, Julie
Source: Pediatrics. Sep2025, Vol. 156 Issue 3, p1-7. 7p.
Subjects: Substance abuse diagnosis, Substance abuse, Iatrogenic diseases, Medical protocols, Consensus (Social sciences), Children's health, Drug withdrawal symptoms, Patient safety, Adolescent health, Critically ill, Patients, Drug therapy, Chronic diseases, Opioid analgesics, Pain management, Intensive care units, Drugs, Critical care medicine, Children
Geographic Terms: United States
Abstract: Opioids are often prescribed to children for pain relief related to procedures, acute injuries, and chronic conditions. Around-the-clock dosing of opioids can produce physiologic opioid dependence within 5 days. According to a 2001 consensus paper from the American Academy of Pain Medicine, American Pain Society, and American Society of Addiction Medicine, dependence is defined as "a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, or administration of an antagonist." The experience of children undergoing iatrogenic withdrawal symptoms is variable and may be mild and go unreported or can be severe and even life threatening. Guidance on opioid withdrawal is available only for adults and primarily for adults with substance use disorders. This report will summarize existing literature and provide readers with information on how to screen for symptoms of iatrogenic opioid withdrawal as well as mechanisms for opioid withdrawal prevention. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Opioids are often prescribed to children for pain relief related to procedures, acute injuries, and chronic conditions. Around-the-clock dosing of opioids can produce physiologic opioid dependence within 5 days. According to a 2001 consensus paper from the American Academy of Pain Medicine, American Pain Society, and American Society of Addiction Medicine, dependence is defined as "a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, or administration of an antagonist." The experience of children undergoing iatrogenic withdrawal symptoms is variable and may be mild and go unreported or can be severe and even life threatening. Guidance on opioid withdrawal is available only for adults and primarily for adults with substance use disorders. This report will summarize existing literature and provide readers with information on how to screen for symptoms of iatrogenic opioid withdrawal as well as mechanisms for opioid withdrawal prevention. [ABSTRACT FROM AUTHOR]
ISSN:00314005
DOI:10.1542/peds.2025-073169