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The Relationship Between Early Term Birth and the Risk of Later Childhood Mental Disorders Within a Pregnancy Cohort.

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Title: The Relationship Between Early Term Birth and the Risk of Later Childhood Mental Disorders Within a Pregnancy Cohort.
Authors: Galbally, Megan (AUTHOR), Watson, Stuart J. (AUTHOR), Newnham, John (AUTHOR), White, Scott (AUTHOR), Watkins, Andrew (AUTHOR), Lewis, Andrew J. (AUTHOR)
Source: Child Psychiatry & Human Development. Oct2025, Vol. 56 Issue 5, p1389-1401. 13p.
Subjects: Gestational age, Anxiety disorders, Premature labor, Birth weight, Cohort analysis, Neural development, Child psychiatry, Attention-deficit hyperactivity disorder
Abstract: This study examines whether gestational age, birth weight, and early term birth is associated with childhood mental disorders in 342 pregnant women recruited at less than 20 weeks gestation and were then followed up until 4 years postpartum, including 93 children born at early term. Women were assessed at recruitment using the Structured Clinical Interview for DSM. At 4 years of age their children were assessed using the Preschool Age Psychiatric Assessment (PAPA) and the Child Behavior Checklist (CBCL). This study found earlier birth predicted an increased risk for anxiety disorders and demonstrated a significant interaction between gestational age and lower birthweight. The risk for ADHD increased with lower gestational age independent of birthweight. In contrast, gestational age was not associated with Oppositional Defiant Disorder, Conduct Disorder, internalizing or externalizing symptoms. These findings highlight the important differences in the association of early term birth and vulnerability for specific mental disorders. [ABSTRACT FROM AUTHOR]
Copyright of Child Psychiatry & Human Development is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The Relationship Between Early Term Birth and the Risk of Later Childhood Mental Disorders Within a Pregnancy Cohort.
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  Data: <searchLink fieldCode="AR" term="%22Galbally%2C+Megan%22">Galbally, Megan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Watson%2C+Stuart+J%2E%22">Watson, Stuart J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Newnham%2C+John%22">Newnham, John</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22White%2C+Scott%22">White, Scott</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Watkins%2C+Andrew%22">Watkins, Andrew</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lewis%2C+Andrew+J%2E%22">Lewis, Andrew J.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Child+Psychiatry+%26+Human+Development%22">Child Psychiatry & Human Development</searchLink>. Oct2025, Vol. 56 Issue 5, p1389-1401. 13p.
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  Data: <searchLink fieldCode="DE" term="%22Gestational+age%22">Gestational age</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety+disorders%22">Anxiety disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Premature+labor%22">Premature labor</searchLink><br /><searchLink fieldCode="DE" term="%22Birth+weight%22">Birth weight</searchLink><br /><searchLink fieldCode="DE" term="%22Cohort+analysis%22">Cohort analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+development%22">Neural development</searchLink><br /><searchLink fieldCode="DE" term="%22Child+psychiatry%22">Child psychiatry</searchLink><br /><searchLink fieldCode="DE" term="%22Attention-deficit+hyperactivity+disorder%22">Attention-deficit hyperactivity disorder</searchLink>
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  Data: This study examines whether gestational age, birth weight, and early term birth is associated with childhood mental disorders in 342 pregnant women recruited at less than 20 weeks gestation and were then followed up until 4 years postpartum, including 93 children born at early term. Women were assessed at recruitment using the Structured Clinical Interview for DSM. At 4 years of age their children were assessed using the Preschool Age Psychiatric Assessment (PAPA) and the Child Behavior Checklist (CBCL). This study found earlier birth predicted an increased risk for anxiety disorders and demonstrated a significant interaction between gestational age and lower birthweight. The risk for ADHD increased with lower gestational age independent of birthweight. In contrast, gestational age was not associated with Oppositional Defiant Disorder, Conduct Disorder, internalizing or externalizing symptoms. These findings highlight the important differences in the association of early term birth and vulnerability for specific mental disorders. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Child Psychiatry & Human Development is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10578-023-01643-5
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      – Code: eng
        Text: English
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      – SubjectFull: Gestational age
        Type: general
      – SubjectFull: Anxiety disorders
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      – SubjectFull: Premature labor
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      – SubjectFull: Birth weight
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              Text: Oct2025
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