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Integration of Measurement-Based Care for Youth Depression and Suicidality Using VitalSign6.

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Title: Integration of Measurement-Based Care for Youth Depression and Suicidality Using VitalSign6.
Authors: Mitchell, Tarrah B. (AUTHOR), Wakefield, Sarah M. (AUTHOR), Rezaeizadeh, Afsaneh (AUTHOR), Minhajuddin, Abu (AUTHOR), Pipes, Ronny (AUTHOR), Mayes, Taryn L. (AUTHOR), Elmore, Joshua S. (AUTHOR), Trivedi, Madhukar H. (AUTHOR)
Source: Child Psychiatry & Human Development. Oct2025, Vol. 56 Issue 5, p1206-1213. 8p.
Subjects: Mental depression, Suicidal ideation, Disease remission, Evidence-based medicine, Medical screening, Therapeutics, Teenagers
Abstract: Depression and suicidality are prevalent in youth and are associated with a range of negative outcomes. The current study aimed to evaluate a measurement-based care (MBC) software (VitalSign6) tool to improve the screening and treatment of depression and suicidality in youth aged 8–17 years within a rural, underserved population. To assess for depression and suicidality, the Patient Health Questionnaire-2 was administered as an initial screen, and the Patient Health Questionnaire-9 Modified for Adolescents (PHQ-9-A) was administered if the initial screen was positive. Data were collected at medical clinics over one year, and descriptive statistics and t-tests or Wilcoxon-Mann-Whitney tests were conducted. A total of 1,984 youth were initially screened (mean age of 13 years; 51.6% female); 24.2% screened positive for depression, and 14.9% endorsed suicidality. Of those who screened positive, the mean PHQ-9-A score was 12.8; 66.9% had PHQ-9-A scores in the moderate to severe range, and 44.2% endorsed suicidality. Almost half of the youth who screened positive for depression had at least one follow-up assessment, and about one quarter achieved remission 4 months after initial screening. Adolescents (12–17 years) had higher PHQ-9-A scores, higher suicidality, and more follow-up assessments than younger youth (8–11 years). Younger youth had higher rates of remission. The widespread use of MBC was feasible in this setting. It is important to utilize MBC to identify and treat youth with depression and suicidality and to do so in younger populations to improve their trajectory over time; VitalSign6 is one tool to help achieve these goals. [ABSTRACT FROM AUTHOR]
Copyright of Child Psychiatry & Human Development is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Integration of Measurement-Based Care for Youth Depression and Suicidality Using VitalSign<superscript>6</superscript>.
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  Data: <searchLink fieldCode="AR" term="%22Mitchell%2C+Tarrah+B%2E%22">Mitchell, Tarrah B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wakefield%2C+Sarah+M%2E%22">Wakefield, Sarah M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rezaeizadeh%2C+Afsaneh%22">Rezaeizadeh, Afsaneh</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Minhajuddin%2C+Abu%22">Minhajuddin, Abu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pipes%2C+Ronny%22">Pipes, Ronny</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mayes%2C+Taryn+L%2E%22">Mayes, Taryn L.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Elmore%2C+Joshua+S%2E%22">Elmore, Joshua S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Trivedi%2C+Madhukar+H%2E%22">Trivedi, Madhukar H.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Child+Psychiatry+%26+Human+Development%22">Child Psychiatry & Human Development</searchLink>. Oct2025, Vol. 56 Issue 5, p1206-1213. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+remission%22">Disease remission</searchLink><br /><searchLink fieldCode="DE" term="%22Evidence-based+medicine%22">Evidence-based medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+screening%22">Medical screening</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Teenagers%22">Teenagers</searchLink>
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  Data: Depression and suicidality are prevalent in youth and are associated with a range of negative outcomes. The current study aimed to evaluate a measurement-based care (MBC) software (VitalSign6) tool to improve the screening and treatment of depression and suicidality in youth aged 8–17 years within a rural, underserved population. To assess for depression and suicidality, the Patient Health Questionnaire-2 was administered as an initial screen, and the Patient Health Questionnaire-9 Modified for Adolescents (PHQ-9-A) was administered if the initial screen was positive. Data were collected at medical clinics over one year, and descriptive statistics and t-tests or Wilcoxon-Mann-Whitney tests were conducted. A total of 1,984 youth were initially screened (mean age of 13 years; 51.6% female); 24.2% screened positive for depression, and 14.9% endorsed suicidality. Of those who screened positive, the mean PHQ-9-A score was 12.8; 66.9% had PHQ-9-A scores in the moderate to severe range, and 44.2% endorsed suicidality. Almost half of the youth who screened positive for depression had at least one follow-up assessment, and about one quarter achieved remission 4 months after initial screening. Adolescents (12–17 years) had higher PHQ-9-A scores, higher suicidality, and more follow-up assessments than younger youth (8–11 years). Younger youth had higher rates of remission. The widespread use of MBC was feasible in this setting. It is important to utilize MBC to identify and treat youth with depression and suicidality and to do so in younger populations to improve their trajectory over time; VitalSign6 is one tool to help achieve these goals. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Child Psychiatry & Human Development is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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