View in EDS

Unilateral change of laryngeal adductor reflex and hiccups resolution after removal of bulbar hemangioblastoma: is there a connection?

Saved in:
Bibliographic Details
Title: Unilateral change of laryngeal adductor reflex and hiccups resolution after removal of bulbar hemangioblastoma: is there a connection?
Authors: Fontana, V. (AUTHOR), Squintani, G. M. (AUTHOR), Badari, A. (AUTHOR), Basaldella, F. (AUTHOR), Sala, F. (AUTHOR), Pinna, G. (AUTHOR), Masotto, B. (AUTHOR)
Source: Neurological Sciences. Nov2025, Vol. 46 Issue 11, p6155-6160. 6p.
Subjects: Medulla oblongata, Hiccups, Surgical excision, Numbness, Brain stem, Intraoperative monitoring
Abstract: Intractable hiccups, although typically benign, occasionally present as a clinical challenge requiring deeper investigation. We report a case of persistent hiccups as the sole manifestation of a cystic hemangioblastoma within the medulla oblongata. Conventional hiccup treatments were ineffective, prompting surgical intervention. We employed intraoperative neurophysiological monitoring of the Laryngeal Adductor Reflex (LAR) during the procedure, revealing intriguing asymmetries in reflex responses. At the end of the surgical excision, we recorded a significant LAR decrease on the left side, without any changes in vocal corticobulbar potentials (vocal coMEPs). Postoperatively, the patient's hiccups ceased, leaving transient pharyngeal hypoesthesia. This case underscores the utility of LAR monitoring and vocal coMEPs in brainstem surgeries and discuss a potential link between post-surgical LAR reduction, and hiccup resolution. Our findings prompt further exploration of the complex neural mechanisms governing hiccups and their therapeutic implications in neurosurgery. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 188779315
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Unilateral change of laryngeal adductor reflex and hiccups resolution after removal of bulbar hemangioblastoma: is there a connection?
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Fontana%2C+V%2E%22">Fontana, V.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Squintani%2C+G%2E+M%2E%22">Squintani, G. M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Badari%2C+A%2E%22">Badari, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Basaldella%2C+F%2E%22">Basaldella, F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sala%2C+F%2E%22">Sala, F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pinna%2C+G%2E%22">Pinna, G.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Masotto%2C+B%2E%22">Masotto, B.</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Nov2025, Vol. 46 Issue 11, p6155-6160. 6p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Medulla+oblongata%22">Medulla oblongata</searchLink><br /><searchLink fieldCode="DE" term="%22Hiccups%22">Hiccups</searchLink><br /><searchLink fieldCode="DE" term="%22Surgical+excision%22">Surgical excision</searchLink><br /><searchLink fieldCode="DE" term="%22Numbness%22">Numbness</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+stem%22">Brain stem</searchLink><br /><searchLink fieldCode="DE" term="%22Intraoperative+monitoring%22">Intraoperative monitoring</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Intractable hiccups, although typically benign, occasionally present as a clinical challenge requiring deeper investigation. We report a case of persistent hiccups as the sole manifestation of a cystic hemangioblastoma within the medulla oblongata. Conventional hiccup treatments were ineffective, prompting surgical intervention. We employed intraoperative neurophysiological monitoring of the Laryngeal Adductor Reflex (LAR) during the procedure, revealing intriguing asymmetries in reflex responses. At the end of the surgical excision, we recorded a significant LAR decrease on the left side, without any changes in vocal corticobulbar potentials (vocal coMEPs). Postoperatively, the patient's hiccups ceased, leaving transient pharyngeal hypoesthesia. This case underscores the utility of LAR monitoring and vocal coMEPs in brainstem surgeries and discuss a potential link between post-surgical LAR reduction, and hiccup resolution. Our findings prompt further exploration of the complex neural mechanisms governing hiccups and their therapeutic implications in neurosurgery. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=188779315
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10072-025-08359-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 6155
    Subjects:
      – SubjectFull: Medulla oblongata
        Type: general
      – SubjectFull: Hiccups
        Type: general
      – SubjectFull: Surgical excision
        Type: general
      – SubjectFull: Numbness
        Type: general
      – SubjectFull: Brain stem
        Type: general
      – SubjectFull: Intraoperative monitoring
        Type: general
    Titles:
      – TitleFull: Unilateral change of laryngeal adductor reflex and hiccups resolution after removal of bulbar hemangioblastoma: is there a connection?
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Fontana, V.
      – PersonEntity:
          Name:
            NameFull: Squintani, G. M.
      – PersonEntity:
          Name:
            NameFull: Badari, A.
      – PersonEntity:
          Name:
            NameFull: Basaldella, F.
      – PersonEntity:
          Name:
            NameFull: Sala, F.
      – PersonEntity:
          Name:
            NameFull: Pinna, G.
      – PersonEntity:
          Name:
            NameFull: Masotto, B.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: Nov2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 15901874
          Numbering:
            – Type: volume
              Value: 46
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Neurological Sciences
              Type: main
ResultId 1