Effects of parental characteristics on the risk of psychopathology in offspring: a 4-year follow-up study.

Saved in:
Bibliographic Details
Title: Effects of parental characteristics on the risk of psychopathology in offspring: a 4-year follow-up study.
Authors: De la Serna, E. (AUTHOR), Moreno, D. (AUTHOR), Sugranyes, G. (AUTHOR), Camprodon-Boadas, P. (AUTHOR), Ilzarbe, D. (AUTHOR), Bigorra, A. (AUTHOR), Mora-Maltas, B. (AUTHOR), Baeza, I. (AUTHOR), Flamarique, I. (AUTHOR), Parrilla, S. (AUTHOR), Díaz-Caneja, C. M. (AUTHOR), Moreno, C. (AUTHOR), Borras, R. (AUTHOR), Torrent, C. (AUTHOR), Garcia-Rizo, C. (AUTHOR), Castro-Fornieles, J. (AUTHOR)
Source: European Child & Adolescent Psychiatry. Oct2025, Vol. 34 Issue 10, p3035-3045. 11p.
Subjects: Risk factors of attention-deficit hyperactivity disorder, Risk assessment, Behavior disorders, Schizophrenia in children, Research funding, Psychology of fathers, Interviewing, Parenting, Descriptive statistics, Multivariate analysis, Parent attitudes, Kaplan-Meier estimator, Longitudinal method, Log-rank test, Statistics, Psychology of mothers, Parents of children with disabilities, Psychoses, Confidence intervals, Psychosocial factors, Pathological psychology, Bipolar disorder in children, Social classes, Disease incidence
Abstract: Offspring of patients diagnosed with schizophrenia (SZoff) or bipolar disorder (BDoff) have double the risk of developing a psychiatric disorder. Here we report the effects of some parental characteristics on the offspring risk of psychopathology at 4-year follow-up. At baseline, 90 BDoff, 41 SZoff and 107 Community Control offspring (CCoff) aged 6 to 17 were included. At 4-year follow-up, 71% of the sample was assessed. Parents' and offspring's psychiatric diagnoses as well as socio-economic status (SES) and global functioning were assessed in addition to parents' ages at childbirth and offspring subclinical psychotic/bipolar symptoms. Kaplan-Meier method and Cox regression analysis were used to assess between-group differences in the cumulative incidence of psychiatric disorders and subclinical psychotic/bipolar symptoms and the association of some offspring and parents' variables with risk of psychopathology and subclinical psychotic/bipolar symptoms. SZoff and BDoff had a higher risk of psychopathology than CCoff at 4-year follow-up. SZoff showed a higher risk for attention deficit hyperactivity disorder (ADHD), disruptive disorders and subclinical psychotic symptoms, whereas BDoff displayed a heightened risk for mood disorders, ADHD and subclinical bipolar symptoms when compared to CCoff. Higher parental psychosocial functioning and SES were associated with a lower prevalence of psychopathology. Both SZoff and BDoff samples have a higher risk for psychopathology but the pattern of this psychopathology seems to be group specific. Longer follow-up studies and larger sample sizes are needed to assess the capacity of psychopathological disorder and subclinical psychotic or bipolar symptoms to predict progression to fully-fledged disorders. [ABSTRACT FROM AUTHOR]
Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 189168596
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Effects of parental characteristics on the risk of psychopathology in offspring: a 4-year follow-up study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22De+la+Serna%2C+E%2E%22">De la Serna, E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Moreno%2C+D%2E%22">Moreno, D.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sugranyes%2C+G%2E%22">Sugranyes, G.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Camprodon-Boadas%2C+P%2E%22">Camprodon-Boadas, P.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ilzarbe%2C+D%2E%22">Ilzarbe, D.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bigorra%2C+A%2E%22">Bigorra, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mora-Maltas%2C+B%2E%22">Mora-Maltas, B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Baeza%2C+I%2E%22">Baeza, I.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Flamarique%2C+I%2E%22">Flamarique, I.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Parrilla%2C+S%2E%22">Parrilla, S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Díaz-Caneja%2C+C%2E+M%2E%22">Díaz-Caneja, C. M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Moreno%2C+C%2E%22">Moreno, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Borras%2C+R%2E%22">Borras, R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Torrent%2C+C%2E%22">Torrent, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Garcia-Rizo%2C+C%2E%22">Garcia-Rizo, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Castro-Fornieles%2C+J%2E%22">Castro-Fornieles, J.</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Child+%26+Adolescent+Psychiatry%22">European Child & Adolescent Psychiatry</searchLink>. Oct2025, Vol. 34 Issue 10, p3035-3045. 11p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Risk+factors+of+attention-deficit+hyperactivity+disorder%22">Risk factors of attention-deficit hyperactivity disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+assessment%22">Risk assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Behavior+disorders%22">Behavior disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia+in+children%22">Schizophrenia in children</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+fathers%22">Psychology of fathers</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Parenting%22">Parenting</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Parent+attitudes%22">Parent attitudes</searchLink><br /><searchLink fieldCode="DE" term="%22Kaplan-Meier+estimator%22">Kaplan-Meier estimator</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Log-rank+test%22">Log-rank test</searchLink><br /><searchLink fieldCode="DE" term="%22Statistics%22">Statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+mothers%22">Psychology of mothers</searchLink><br /><searchLink fieldCode="DE" term="%22Parents+of+children+with+disabilities%22">Parents of children with disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Psychosocial+factors%22">Psychosocial factors</searchLink><br /><searchLink fieldCode="DE" term="%22Pathological+psychology%22">Pathological psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Bipolar+disorder+in+children%22">Bipolar disorder in children</searchLink><br /><searchLink fieldCode="DE" term="%22Social+classes%22">Social classes</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+incidence%22">Disease incidence</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Offspring of patients diagnosed with schizophrenia (SZoff) or bipolar disorder (BDoff) have double the risk of developing a psychiatric disorder. Here we report the effects of some parental characteristics on the offspring risk of psychopathology at 4-year follow-up. At baseline, 90 BDoff, 41 SZoff and 107 Community Control offspring (CCoff) aged 6 to 17 were included. At 4-year follow-up, 71% of the sample was assessed. Parents' and offspring's psychiatric diagnoses as well as socio-economic status (SES) and global functioning were assessed in addition to parents' ages at childbirth and offspring subclinical psychotic/bipolar symptoms. Kaplan-Meier method and Cox regression analysis were used to assess between-group differences in the cumulative incidence of psychiatric disorders and subclinical psychotic/bipolar symptoms and the association of some offspring and parents' variables with risk of psychopathology and subclinical psychotic/bipolar symptoms. SZoff and BDoff had a higher risk of psychopathology than CCoff at 4-year follow-up. SZoff showed a higher risk for attention deficit hyperactivity disorder (ADHD), disruptive disorders and subclinical psychotic symptoms, whereas BDoff displayed a heightened risk for mood disorders, ADHD and subclinical bipolar symptoms when compared to CCoff. Higher parental psychosocial functioning and SES were associated with a lower prevalence of psychopathology. Both SZoff and BDoff samples have a higher risk for psychopathology but the pattern of this psychopathology seems to be group specific. Longer follow-up studies and larger sample sizes are needed to assess the capacity of psychopathological disorder and subclinical psychotic or bipolar symptoms to predict progression to fully-fledged disorders. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=189168596
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00787-025-02719-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 3035
    Subjects:
      – SubjectFull: Risk factors of attention-deficit hyperactivity disorder
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Behavior disorders
        Type: general
      – SubjectFull: Schizophrenia in children
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Psychology of fathers
        Type: general
      – SubjectFull: Interviewing
        Type: general
      – SubjectFull: Parenting
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
      – SubjectFull: Parent attitudes
        Type: general
      – SubjectFull: Kaplan-Meier estimator
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Log-rank test
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Psychology of mothers
        Type: general
      – SubjectFull: Parents of children with disabilities
        Type: general
      – SubjectFull: Psychoses
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Psychosocial factors
        Type: general
      – SubjectFull: Pathological psychology
        Type: general
      – SubjectFull: Bipolar disorder in children
        Type: general
      – SubjectFull: Social classes
        Type: general
      – SubjectFull: Disease incidence
        Type: general
    Titles:
      – TitleFull: Effects of parental characteristics on the risk of psychopathology in offspring: a 4-year follow-up study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: De la Serna, E.
      – PersonEntity:
          Name:
            NameFull: Moreno, D.
      – PersonEntity:
          Name:
            NameFull: Sugranyes, G.
      – PersonEntity:
          Name:
            NameFull: Camprodon-Boadas, P.
      – PersonEntity:
          Name:
            NameFull: Ilzarbe, D.
      – PersonEntity:
          Name:
            NameFull: Bigorra, A.
      – PersonEntity:
          Name:
            NameFull: Mora-Maltas, B.
      – PersonEntity:
          Name:
            NameFull: Baeza, I.
      – PersonEntity:
          Name:
            NameFull: Flamarique, I.
      – PersonEntity:
          Name:
            NameFull: Parrilla, S.
      – PersonEntity:
          Name:
            NameFull: Díaz-Caneja, C. M.
      – PersonEntity:
          Name:
            NameFull: Moreno, C.
      – PersonEntity:
          Name:
            NameFull: Borras, R.
      – PersonEntity:
          Name:
            NameFull: Torrent, C.
      – PersonEntity:
          Name:
            NameFull: Garcia-Rizo, C.
      – PersonEntity:
          Name:
            NameFull: Castro-Fornieles, J.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 10188827
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: European Child & Adolescent Psychiatry
              Type: main
ResultId 1