Postpartum Tubal Sterilization in Sickle Cell Disease in the 2012–2019 National Inpatient Sample.

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Title: Postpartum Tubal Sterilization in Sickle Cell Disease in the 2012–2019 National Inpatient Sample.
Authors: Luo, Amy (AUTHOR), Gemmill, Alison (AUTHOR), Scott, Jayla L. (AUTHOR), Burke, Anne E. (AUTHOR), Pecker, Lydia H. (AUTHOR)
Source: Journal of Women's Health (15409996). Dec2025, Vol. 34 Issue 12, p1558-1568. 11p.
Subjects: Cross-sectional method, Sickle cell anemia, Research funding, Puerperium, Logistic regression analysis, High-risk pregnancy, Retrospective studies, Descriptive statistics, Multivariate analysis, Tubal sterilization, Contraception, Pregnancy complications, Comparative studies, Confidence intervals, Data analysis software, Disease complications
Geographic Terms: United States
Abstract: Background: Sickle cell disease (SCD) is associated with high-risk pregnancy and low rates of hormonal contraception use. Intersectional vulnerabilities among individuals with SCD in the United States raise historically and socially contingent questions about tubal sterilization (TS), yet immediate postpartum TS rates among individuals with SCD remain unknown. Methods: Using the 2012–2019 National Inpatient Sample, we conducted a repeated cross-sectional study to estimate the rate of TS among delivery hospitalizations for people with SCD, without SCD (non-SCD), Black people with and without SCD, and people with cystic fibrosis (CF). Logistic regression models estimated the adjusted odds of TS between SCD and comparison groups. Interaction analyses examined whether severe maternal morbidity (SMM) modified the association between TS and SCD. Results: After adjusting for patient and hospital characteristics, SCD had higher odds of TS compared with non-SCD deliveries (adjusted odds ratio [aOR] = 1.38 [1.06, 1.79]). Among deliveries coded with Black race, SCD deliveries had higher odds of TS than non-SCD deliveries (aOR = 1.42 [1.06, 1.90]). There was no difference in the odds of TS between SCD and CF deliveries (aOR = 1.0 [0.51, 2.24]). SMM more than doubled the odds of TS in SCD deliveries (interaction: aOR = 2.34 [1.57, 3.47]; aOR = 2.14 [1.40, 3.24] in Black race deliveries). Conclusion: Even after accounting for patient and hospital characteristics, people with SCD have higher odds of immediate postpartum TS compared with comparison groups. Possibly, SMM severity, patient preference, or clinician recommendations inform this finding. SMM is three to seven times more common in SCD than non-SCD pregnancies and may be a modifiable risk factor for TS in SCD deliveries. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Women's Health (15409996) is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
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PubTypeId: academicJournal
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  Label: Title
  Group: Ti
  Data: Postpartum Tubal Sterilization in Sickle Cell Disease in the 2012–2019 National Inpatient Sample.
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  Data: <searchLink fieldCode="AR" term="%22Luo%2C+Amy%22">Luo, Amy</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gemmill%2C+Alison%22">Gemmill, Alison</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Scott%2C+Jayla+L%2E%22">Scott, Jayla L.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burke%2C+Anne+E%2E%22">Burke, Anne E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pecker%2C+Lydia+H%2E%22">Pecker, Lydia H.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Women's+Health+%2815409996%29%22">Journal of Women's Health (15409996)</searchLink>. Dec2025, Vol. 34 Issue 12, p1558-1568. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Sickle+cell+anemia%22">Sickle cell anemia</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Puerperium%22">Puerperium</searchLink><br /><searchLink fieldCode="DE" term="%22Logistic+regression+analysis%22">Logistic regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22High-risk+pregnancy%22">High-risk pregnancy</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Tubal+sterilization%22">Tubal sterilization</searchLink><br /><searchLink fieldCode="DE" term="%22Contraception%22">Contraception</searchLink><br /><searchLink fieldCode="DE" term="%22Pregnancy+complications%22">Pregnancy complications</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink>
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  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22United+States%22">United States</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Sickle cell disease (SCD) is associated with high-risk pregnancy and low rates of hormonal contraception use. Intersectional vulnerabilities among individuals with SCD in the United States raise historically and socially contingent questions about tubal sterilization (TS), yet immediate postpartum TS rates among individuals with SCD remain unknown. Methods: Using the 2012–2019 National Inpatient Sample, we conducted a repeated cross-sectional study to estimate the rate of TS among delivery hospitalizations for people with SCD, without SCD (non-SCD), Black people with and without SCD, and people with cystic fibrosis (CF). Logistic regression models estimated the adjusted odds of TS between SCD and comparison groups. Interaction analyses examined whether severe maternal morbidity (SMM) modified the association between TS and SCD. Results: After adjusting for patient and hospital characteristics, SCD had higher odds of TS compared with non-SCD deliveries (adjusted odds ratio [aOR] = 1.38 [1.06, 1.79]). Among deliveries coded with Black race, SCD deliveries had higher odds of TS than non-SCD deliveries (aOR = 1.42 [1.06, 1.90]). There was no difference in the odds of TS between SCD and CF deliveries (aOR = 1.0 [0.51, 2.24]). SMM more than doubled the odds of TS in SCD deliveries (interaction: aOR = 2.34 [1.57, 3.47]; aOR = 2.14 [1.40, 3.24] in Black race deliveries). Conclusion: Even after accounting for patient and hospital characteristics, people with SCD have higher odds of immediate postpartum TS compared with comparison groups. Possibly, SMM severity, patient preference, or clinician recommendations inform this finding. SMM is three to seven times more common in SCD than non-SCD pregnancies and may be a modifiable risk factor for TS in SCD deliveries. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Women's Health (15409996) is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1177/15409996251359820
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 1558
    Subjects:
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Sickle cell anemia
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Puerperium
        Type: general
      – SubjectFull: Logistic regression analysis
        Type: general
      – SubjectFull: High-risk pregnancy
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
      – SubjectFull: Tubal sterilization
        Type: general
      – SubjectFull: Contraception
        Type: general
      – SubjectFull: Pregnancy complications
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Disease complications
        Type: general
      – SubjectFull: United States
        Type: general
    Titles:
      – TitleFull: Postpartum Tubal Sterilization in Sickle Cell Disease in the 2012–2019 National Inpatient Sample.
        Type: main
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            NameFull: Luo, Amy
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            NameFull: Gemmill, Alison
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            NameFull: Scott, Jayla L.
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            NameFull: Burke, Anne E.
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              M: 12
              Text: Dec2025
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              Y: 2025
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