Cognitive Predictors of Internalizing Symptoms in Clinically Anxious Youth.

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Title: Cognitive Predictors of Internalizing Symptoms in Clinically Anxious Youth.
Authors: Amarneh, Dania Y. (AUTHOR), Zvolensky, Michael J. (AUTHOR), Storch, Eric A. (AUTHOR), Viana, Andres G. (AUTHOR)
Source: Cognitive Therapy & Research. Dec2025, Vol. 49 Issue 6, p1322-1336. 15p.
Subjects: Anxiety sensitivity, Cognitive bias, Disease risk factors, Symptom burden, Adjustment disorders, Youth health
Abstract: Background: Internalizing disorders are the most common psychiatric disorders in youth and are associated with a host of deleterious outcomes (e.g., self-harm, substance use, interpersonal difficulties), highlighting the critical need for identifying risk factors that confer risk for these disorders. The present study investigated the unique and shared roles of two prominent cognitive biases—anxiety sensitivity and interpretation biases—as predictors of internalizing symptom severity in clinically anxious youth, above and beyond the effects of negative emotionality and after accounting for sociodemographic covariates. Method: A diverse sample of clinically anxious youth (N = 105; Mage = 10.09 years, SD = 1.22; 56.7% female; 49% ethnic minority) completed a diagnostic interview and self-report measures of interpretation biases, anxiety sensitivity, and internalizing symptom severity. Results: Hierarchical regression analyses revealed that both anxiety sensitivity (b = 0.77, 95% CI [0.53, 1.00], sr2 = 0.11) and interpretation biases (b = 0.21, 95% CI [0.11, 0.30], sr2 = 0.05) accounted for an additional 22% of unique variance in internalizing symptom severity (p <.001), above and beyond the effects of negative emotionality. Post hoc exploratory analyses identified the disease and social concerns facets of anxiety sensitivity, and the overgeneralization facet of interpretation biases, as predictors of internalizing symptoms. Conclusion: Future research should examine whether targeting cognitive biases would be beneficial among temperamentally labile youth. [ABSTRACT FROM AUTHOR]
Copyright of Cognitive Therapy & Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Cognitive Predictors of Internalizing Symptoms in Clinically Anxious Youth.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Amarneh%2C+Dania+Y%2E%22&quot;&gt;Amarneh, Dania Y.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zvolensky%2C+Michael+J%2E%22&quot;&gt;Zvolensky, Michael J.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Storch%2C+Eric+A%2E%22&quot;&gt;Storch, Eric A.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Viana%2C+Andres+G%2E%22&quot;&gt;Viana, Andres G.&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Cognitive+Therapy+%26+Research%22&quot;&gt;Cognitive Therapy &amp; Research&lt;/searchLink&gt;. Dec2025, Vol. 49 Issue 6, p1322-1336. 15p.
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– Name: Abstract
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  Data: Background: Internalizing disorders are the most common psychiatric disorders in youth and are associated with a host of deleterious outcomes (e.g., self-harm, substance use, interpersonal difficulties), highlighting the critical need for identifying risk factors that confer risk for these disorders. The present study investigated the unique and shared roles of two prominent cognitive biases—anxiety sensitivity and interpretation biases—as predictors of internalizing symptom severity in clinically anxious youth, above and beyond the effects of negative emotionality and after accounting for sociodemographic covariates. Method: A diverse sample of clinically anxious youth (N = 105; Mage = 10.09 years, SD = 1.22; 56.7% female; 49% ethnic minority) completed a diagnostic interview and self-report measures of interpretation biases, anxiety sensitivity, and internalizing symptom severity. Results: Hierarchical regression analyses revealed that both anxiety sensitivity (b = 0.77, 95% CI [0.53, 1.00], sr2 = 0.11) and interpretation biases (b = 0.21, 95% CI [0.11, 0.30], sr2 = 0.05) accounted for an additional 22% of unique variance in internalizing symptom severity (p &lt;.001), above and beyond the effects of negative emotionality. Post hoc exploratory analyses identified the disease and social concerns facets of anxiety sensitivity, and the overgeneralization facet of interpretation biases, as predictors of internalizing symptoms. Conclusion: Future research should examine whether targeting cognitive biases would be beneficial among temperamentally labile youth. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Cognitive Therapy &amp; Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10608-025-10612-2
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        Text: English
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        Type: general
      – SubjectFull: Cognitive bias
        Type: general
      – SubjectFull: Disease risk factors
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      – SubjectFull: Symptom burden
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      – SubjectFull: Adjustment disorders
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      – SubjectFull: Youth health
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    Titles:
      – TitleFull: Cognitive Predictors of Internalizing Symptoms in Clinically Anxious Youth.
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            NameFull: Zvolensky, Michael J.
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              Text: Dec2025
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              Y: 2025
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