Bibliographic Details
| Title: |
Patients With Dementia Undergoing High‐Risk Inpatient Surgery Have Poor Outcomes. |
| Authors: |
Shah, Samir K. (AUTHOR), Xiang, Lingwei (AUTHOR), Adler, Rachel R. (AUTHOR), Clark, Clancy J. (AUTHOR), Cooper, Zara (AUTHOR), Finlayson, Emily (AUTHOR), Mitchell, Susan L. (AUTHOR), Kim, Dae Hyun (AUTHOR), Lin, Kueiyu Joshua (AUTHOR), Lipsitz, Stuart R. (AUTHOR), Weissman, Joel S. (AUTHOR) |
| Source: |
Journal of the American Geriatrics Society. Nov2025, Vol. 73 Issue 11, p3434-3443. 10p. |
| Subjects: |
Risk assessment, Research funding, Alzheimer's disease, Hospital care, Medicare, Fee for service (Medical fees), Fisher exact test, Logistic regression analysis, Health insurance, Treatment effectiveness, Retrospective studies, Descriptive statistics, Mann Whitney U Test, Chi-squared test, Hospital mortality, Discharge planning, Decision making in clinical medicine, Operative surgery, Surgical complications, Longitudinal method, Odds ratio, Nursing care facilities, Medical records, Acquisition of data, Dementia, Data analysis software, Confidence intervals, Length of stay in hospitals, Dementia patients, Regression analysis, Proportional hazards models, Feeding tubes, Advance directives (Medical care), Disease risk factors, Disease complications |
| Geographic Terms: |
United States |
| Abstract: |
Background: Surgery is common among patients living with dementia, and understanding outcomes may help decision‐making. We compared patients' and utilization outcomes after high‐risk surgery among patients with and without dementia. Methods: In this retrospective national cohort study, we compared outcomes of Medicare fee‐for‐service beneficiaries 66 years or older who underwent high‐risk inpatient surgery (i.e., with an inpatient mortality of at least 1%) from January 1, 2017 to September 30, 2018. We examined 90‐ and 30‐day all‐cause mortality, major complications, discharge to a higher level of care, intensive end‐of‐life interventions, and prolonged skilled nursing facility (SNF) stay. We used generalized estimating equations regression modeling and competing risks analysis. Results: Among 19,998,187 beneficiaries, we identified 859,570 who had fee‐for‐service coverage and were 66 years or older at the time of a high‐risk surgery. Of these, 124,822 (14.5%) had a diagnosis of dementia. Female sex accounted for 81,252 (65.1%) of the dementia cohort. Four of five of the most common procedures were related to femur fracture and cardiac surgery in the dementia and non‐dementia cohorts. Ninety‐day mortality was worse among patients with dementia: 22.8% versus 9.3% (adjusted odds ratio [aOR] 1.82, 95% confidence interval [CI] 1.78–1.85). Patients with dementia were also more likely to have major complications (51.6% vs. 38.5%, aOR 1.19, 95% CI 1.17–1.20), be discharged to a higher level of care (75.1% vs. 41.3%, aOR 1.49, 95% CI 1.44–1.53), and have a prolonged SNF stay (3.7% vs. 1.4%, aOR 1.80, 95% CI 1.69–1.91). Although patients with ADRD were overall less likely to receive intensive interventions during the index admission and at 90 days, they were more likely to receive feeding tubes (aOR 1.22, 95% CI 1.17–1.28). Conclusion: Persons living with dementia experience a broad range of worse outcomes after high‐risk surgery compared to those without dementia. These data may be used for decision‐making. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
