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The Emotion and Symptom‐Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial.

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Title: The Emotion and Symptom‐Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial.
Authors: Jibb, Lindsay A. (AUTHOR), Yu, Ally (AUTHOR), Nanos, Stephanie (AUTHOR), Malfitano, Carmine (AUTHOR), Foran, Laura (AUTHOR), Hunt, Kate (AUTHOR), Malakian, Argin (AUTHOR), Zimmermann, Camilla (AUTHOR), Schultebraucks, Katharina (AUTHOR), Pham, Nhu‐An (AUTHOR), Rydall, Anne (AUTHOR), Alexander, Sarah (AUTHOR), Rodin, Gary (AUTHOR)
Source: Psycho-Oncology. Nov2025, Vol. 34 Issue 11, p1-13. 13p.
Subjects: Acute leukemia, Parents, Feasibility studies, Treatment effectiveness, Post-traumatic stress, Services for caregivers, Psychotherapy, Social support
Abstract: Background: Parents of children newly diagnosed with acute leukemia (AL) experience significant traumatic stress that adversely affects their well‐being, caregiving capacity, and family functioning. However, rigorous evidence of the feasibility and effectiveness of psychosocial interventions for this group remains limited. Aims: To evaluate the study feasibility and acceptability of Emotion And Symptom‐focused Engagement (EASE), a brief, manualized psychotherapeutic intervention designed to mitigate traumatic stress symptoms in individuals facing a life‐threatening illness or in their close family member. Methods: This single‐arm, pre‐post feasibility study recruited parents of children with AL who participated in EASE sessions delivered by trained clinicians. Measures of traumatic stress, depressive symptoms, and other psychosocial outcomes were obtained at baseline, 3‐ and 6‐months. Feasibility was assessed based on enrollment, attrition, adherence to EASE, and questionnaire completion rates, with predefined criteria guiding trial progression. Acceptability was evaluated via thematic analysis of qualitative interviews. Descriptive statistics summarized outcome data. Results: Of 59 parents approached, 40 (68%) enrolled. The study attrition rate was 15%. Participants attended six EASE sessions on average, with 88% receiving the minimum dose of three sessions. Outcome measures were completed by ≥ 78% of participants at each timepoint. Qualitative findings showed that EASE was well‐received and provided emotional relief and enhanced coping to parents. Virtual intervention delivery and flexible scheduling facilitated engagement. Conclusion: EASE is a feasible and acceptable intervention for parents of children with newly diagnosed AL, addressing critical caregiver support needs. Randomized controlled trials are warranted to evaluate its efficacy in reducing traumatic stress and improving caregiver well‐being. Trial registration: NCT05236296 ClinicalTrials.gov. [ABSTRACT FROM AUTHOR]
Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The Emotion and Symptom‐Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial.
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  Data: <searchLink fieldCode="AR" term="%22Jibb%2C+Lindsay+A%2E%22">Jibb, Lindsay A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yu%2C+Ally%22">Yu, Ally</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nanos%2C+Stephanie%22">Nanos, Stephanie</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Malfitano%2C+Carmine%22">Malfitano, Carmine</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Foran%2C+Laura%22">Foran, Laura</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hunt%2C+Kate%22">Hunt, Kate</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Malakian%2C+Argin%22">Malakian, Argin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zimmermann%2C+Camilla%22">Zimmermann, Camilla</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schultebraucks%2C+Katharina%22">Schultebraucks, Katharina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pham%2C+Nhu‐An%22">Pham, Nhu‐An</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rydall%2C+Anne%22">Rydall, Anne</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alexander%2C+Sarah%22">Alexander, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rodin%2C+Gary%22">Rodin, Gary</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Psycho-Oncology%22">Psycho-Oncology</searchLink>. Nov2025, Vol. 34 Issue 11, p1-13. 13p.
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  Data: <searchLink fieldCode="DE" term="%22Acute+leukemia%22">Acute leukemia</searchLink><br /><searchLink fieldCode="DE" term="%22Parents%22">Parents</searchLink><br /><searchLink fieldCode="DE" term="%22Feasibility+studies%22">Feasibility studies</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Post-traumatic+stress%22">Post-traumatic stress</searchLink><br /><searchLink fieldCode="DE" term="%22Services+for+caregivers%22">Services for caregivers</searchLink><br /><searchLink fieldCode="DE" term="%22Psychotherapy%22">Psychotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Social+support%22">Social support</searchLink>
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  Label: Abstract
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  Data: Background: Parents of children newly diagnosed with acute leukemia (AL) experience significant traumatic stress that adversely affects their well‐being, caregiving capacity, and family functioning. However, rigorous evidence of the feasibility and effectiveness of psychosocial interventions for this group remains limited. Aims: To evaluate the study feasibility and acceptability of Emotion And Symptom‐focused Engagement (EASE), a brief, manualized psychotherapeutic intervention designed to mitigate traumatic stress symptoms in individuals facing a life‐threatening illness or in their close family member. Methods: This single‐arm, pre‐post feasibility study recruited parents of children with AL who participated in EASE sessions delivered by trained clinicians. Measures of traumatic stress, depressive symptoms, and other psychosocial outcomes were obtained at baseline, 3‐ and 6‐months. Feasibility was assessed based on enrollment, attrition, adherence to EASE, and questionnaire completion rates, with predefined criteria guiding trial progression. Acceptability was evaluated via thematic analysis of qualitative interviews. Descriptive statistics summarized outcome data. Results: Of 59 parents approached, 40 (68%) enrolled. The study attrition rate was 15%. Participants attended six EASE sessions on average, with 88% receiving the minimum dose of three sessions. Outcome measures were completed by ≥ 78% of participants at each timepoint. Qualitative findings showed that EASE was well‐received and provided emotional relief and enhanced coping to parents. Virtual intervention delivery and flexible scheduling facilitated engagement. Conclusion: EASE is a feasible and acceptable intervention for parents of children with newly diagnosed AL, addressing critical caregiver support needs. Randomized controlled trials are warranted to evaluate its efficacy in reducing traumatic stress and improving caregiver well‐being. Trial registration: NCT05236296 ClinicalTrials.gov. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/pon.70310
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      – Code: eng
        Text: English
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        PageCount: 13
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    Subjects:
      – SubjectFull: Acute leukemia
        Type: general
      – SubjectFull: Parents
        Type: general
      – SubjectFull: Feasibility studies
        Type: general
      – SubjectFull: Treatment effectiveness
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      – SubjectFull: Post-traumatic stress
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      – SubjectFull: Services for caregivers
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      – SubjectFull: Social support
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              Text: Nov2025
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