Opioid Misuse by Adults with Chronic Pain: The Impact of Illness and Medication Beliefs.

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Title: Opioid Misuse by Adults with Chronic Pain: The Impact of Illness and Medication Beliefs.
Authors: Cannon, Margeaux E. (AUTHOR), Martin, Jessica L. (AUTHOR), McAndrew, Lisa M. (AUTHOR), Brenner, Rachel E. (AUTHOR)
Source: International Journal of Behavioral Medicine. Oct2025, Vol. 32 Issue 5, p668-677. 10p.
Subjects: Substance abuse risk factors, Chronic pain & psychology, Risk assessment, Cross-sectional method, Self-evaluation, Pain measurement, Goodness-of-fit tests, Pearson correlation (Statistics), Attitudes toward illness, Research funding, Cronbach's alpha, Questionnaires, Classification of mental disorders, Severity of illness index, Path analysis (Statistics), Descriptive statistics, Narcotics, Opioid analgesics, Statistics, Health Belief Model, Factor analysis, Confidence intervals, Data analysis software, Mental depression, Backache, Adults
Geographic Terms: United States
Abstract: Background: Why do some adults with chronic pain misuse their prescription opioids when others do not? Based on the extended Common-Sense Model, the study evaluated whether adults' beliefs about their pain have an indirect effect on risk of opioid misuse through beliefs about opioids when controlling for depression. Methods: The sample included 297 adult participants in the U.S. recruited from Prolific, an online crowdsourcing website. Study measures included the Illness Perception Questionnaire-Revised (IPQ-R; protective and threat-related illness beliefs about chronic pain), the Beliefs about Medicines Questionnaire-Specific subscale (BMQ-Specific; concern and necessity medication beliefs about prescription opioids), and the Current Opioid Misuse Measure (COMM; risk of current opioid misuse). This cross-sectional parallel mediation analysis was conducted using MPlus. Results: After controlling for depression, the indirect effect of protective illness beliefs on opioid misuse risk through concern medication beliefs (b = -0.01, 95% CI (-0. 038, -0.001), and the indirect effect of threat-related illness beliefs on opioid misuse risk through necessity medication beliefs (b = 0.02, 95% CI (0.004, 0.036) were significant. The full model explained 35% of the variance of opioid misuse risk. Conclusions: Adults with chronic pain with stronger protective beliefs about pain were less likely to have concerns about their opioids and were at lower risk for opioid misuse, while those with greater threat-related beliefs about pain were more likely to believe that their opioids were necessary and be at greater risk for opioid misuse. Results have implications for medical and mental health providers and future research. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Opioid Misuse by Adults with Chronic Pain: The Impact of Illness and Medication Beliefs.
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Behavioral+Medicine%22">International Journal of Behavioral Medicine</searchLink>. Oct2025, Vol. 32 Issue 5, p668-677. 10p.
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  Label: Abstract
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  Data: Background: Why do some adults with chronic pain misuse their prescription opioids when others do not? Based on the extended Common-Sense Model, the study evaluated whether adults' beliefs about their pain have an indirect effect on risk of opioid misuse through beliefs about opioids when controlling for depression. Methods: The sample included 297 adult participants in the U.S. recruited from Prolific, an online crowdsourcing website. Study measures included the Illness Perception Questionnaire-Revised (IPQ-R; protective and threat-related illness beliefs about chronic pain), the Beliefs about Medicines Questionnaire-Specific subscale (BMQ-Specific; concern and necessity medication beliefs about prescription opioids), and the Current Opioid Misuse Measure (COMM; risk of current opioid misuse). This cross-sectional parallel mediation analysis was conducted using MPlus. Results: After controlling for depression, the indirect effect of protective illness beliefs on opioid misuse risk through concern medication beliefs (b = -0.01, 95% CI (-0. 038, -0.001), and the indirect effect of threat-related illness beliefs on opioid misuse risk through necessity medication beliefs (b = 0.02, 95% CI (0.004, 0.036) were significant. The full model explained 35% of the variance of opioid misuse risk. Conclusions: Adults with chronic pain with stronger protective beliefs about pain were less likely to have concerns about their opioids and were at lower risk for opioid misuse, while those with greater threat-related beliefs about pain were more likely to believe that their opioids were necessary and be at greater risk for opioid misuse. Results have implications for medical and mental health providers and future research. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of International Journal of Behavioral Medicine is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1007/s12529-024-10324-z
    Languages:
      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 668
    Subjects:
      – SubjectFull: Substance abuse risk factors
        Type: general
      – SubjectFull: Chronic pain & psychology
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Pain measurement
        Type: general
      – SubjectFull: Goodness-of-fit tests
        Type: general
      – SubjectFull: Pearson correlation (Statistics)
        Type: general
      – SubjectFull: Attitudes toward illness
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Cronbach's alpha
        Type: general
      – SubjectFull: Questionnaires
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      – SubjectFull: Classification of mental disorders
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      – SubjectFull: Severity of illness index
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      – SubjectFull: Path analysis (Statistics)
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Narcotics
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      – SubjectFull: Opioid analgesics
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      – SubjectFull: Statistics
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      – SubjectFull: Health Belief Model
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      – SubjectFull: Factor analysis
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Mental depression
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      – SubjectFull: Backache
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      – SubjectFull: Adults
        Type: general
      – SubjectFull: United States
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      – TitleFull: Opioid Misuse by Adults with Chronic Pain: The Impact of Illness and Medication Beliefs.
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              Text: Oct2025
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