The effects of music therapy on pain and anxiety in young nulliparous patients undergoing laparoscopic cystectomy for endometriosis: a randomized controlled trial.

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Title: The effects of music therapy on pain and anxiety in young nulliparous patients undergoing laparoscopic cystectomy for endometriosis: a randomized controlled trial.
Authors: Li, Wenwei (AUTHOR), Feng, Huiyan (AUTHOR), Yang, Xiaohui (AUTHOR), Meng, Yue (AUTHOR), Yang, Yuebo (AUTHOR), Ye, Qingjian (AUTHOR)
Source: Journal of Psychosomatic Obstetrics & Gynecology. Dec2025, Vol. 46 Issue 1, p1-10. 10p.
Subjects: Music therapy, Anxiety treatment, Females, Pain management, Endometriosis, Patients, Randomized controlled trials, Surgery
Abstract: Background: Endometriosis (EMS) is associated with a markedly increased incidence of depression and anxiety, primarily due to cyclic pain, concerns about infertility from impaired ovarian function, and fear of disease recurrence. Surgery and its associated pain may trigger both emotional and physiological stress responses. Young, nulliparous patients with fertility intentions often experience additional psychological burdens related to surgical safety, postoperative recovery, and the potential impact on future fertility. Music has been shown to promote relaxation, reduce tension and anxiety, and alleviate pain. However, no studies have evaluated the postoperative effects of music therapy in this specific patient population. Objective: To investigate whether music therapy can effectively reduce postoperative pain and alleviate perioperative anxiety in young patients with fertility desires undergoing laparoscopic cystectomy for endometriotic ovarian cysts, and to explore its potential as a simple, non-pharmacological intervention. Methods/Design: A single-center, two-arm, single-masked randomized controlled trial (RCT). Setting: The Third Affiliated Hospital of Sun Yat-sen University (a teaching hospital). Participants: A total of 149 patients were included for analysis, with 75 assigned to the music group and 74 to the control group. Intervention: Perioperative music therapy administered to young, nulliparous patients with fertility intentions undergoing laparoscopic cystectomy for EMS. Results: One participant withdrew during follow-up, and 149 patients were included in the final analysis. Baseline characteristics—including age, BMI, marital status, preoperative VAS scores, and GAD-7 scores and anxiety levels—showed no significant differences between groups. Postoperative VAS scores at 6 h (p = 0.20), Day 1 (p = 0.438), Day 3 (p = 0.714), and Day 7 (p = 0.899) revealed no significant differences. Similarly, GAD-7 scores and anxiety severity levels on postoperative Day 1 (p = 0.541; p = 0.984), Day 3 (p = 0.287; p = 0.436), and Day 7 (p = 0.468; p = 0.703) showed no statistical significance between groups. Conclusion: Music therapy may serve as an adjunctive intervention for young, nulliparous patients with fertility intentions undergoing laparoscopic cystectomy for endometriosis; however, no significant effects were observed in reducing perioperative anxiety or postoperative pain in this population. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: The effects of music therapy on pain and anxiety in young nulliparous patients undergoing laparoscopic cystectomy for endometriosis: a randomized controlled trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Li%2C+Wenwei%22">Li, Wenwei</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Feng%2C+Huiyan%22">Feng, Huiyan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Xiaohui%22">Yang, Xiaohui</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Meng%2C+Yue%22">Meng, Yue</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Yuebo%22">Yang, Yuebo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ye%2C+Qingjian%22">Ye, Qingjian</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Psychosomatic+Obstetrics+%26+Gynecology%22">Journal of Psychosomatic Obstetrics & Gynecology</searchLink>. Dec2025, Vol. 46 Issue 1, p1-10. 10p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Music+therapy%22">Music therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety+treatment%22">Anxiety treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Females%22">Females</searchLink><br /><searchLink fieldCode="DE" term="%22Pain+management%22">Pain management</searchLink><br /><searchLink fieldCode="DE" term="%22Endometriosis%22">Endometriosis</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Surgery%22">Surgery</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Endometriosis (EMS) is associated with a markedly increased incidence of depression and anxiety, primarily due to cyclic pain, concerns about infertility from impaired ovarian function, and fear of disease recurrence. Surgery and its associated pain may trigger both emotional and physiological stress responses. Young, nulliparous patients with fertility intentions often experience additional psychological burdens related to surgical safety, postoperative recovery, and the potential impact on future fertility. Music has been shown to promote relaxation, reduce tension and anxiety, and alleviate pain. However, no studies have evaluated the postoperative effects of music therapy in this specific patient population. Objective: To investigate whether music therapy can effectively reduce postoperative pain and alleviate perioperative anxiety in young patients with fertility desires undergoing laparoscopic cystectomy for endometriotic ovarian cysts, and to explore its potential as a simple, non-pharmacological intervention. Methods/Design: A single-center, two-arm, single-masked randomized controlled trial (RCT). Setting: The Third Affiliated Hospital of Sun Yat-sen University (a teaching hospital). Participants: A total of 149 patients were included for analysis, with 75 assigned to the music group and 74 to the control group. Intervention: Perioperative music therapy administered to young, nulliparous patients with fertility intentions undergoing laparoscopic cystectomy for EMS. Results: One participant withdrew during follow-up, and 149 patients were included in the final analysis. Baseline characteristics—including age, BMI, marital status, preoperative VAS scores, and GAD-7 scores and anxiety levels—showed no significant differences between groups. Postoperative VAS scores at 6 h (p = 0.20), Day 1 (p = 0.438), Day 3 (p = 0.714), and Day 7 (p = 0.899) revealed no significant differences. Similarly, GAD-7 scores and anxiety severity levels on postoperative Day 1 (p = 0.541; p = 0.984), Day 3 (p = 0.287; p = 0.436), and Day 7 (p = 0.468; p = 0.703) showed no statistical significance between groups. Conclusion: Music therapy may serve as an adjunctive intervention for young, nulliparous patients with fertility intentions undergoing laparoscopic cystectomy for endometriosis; however, no significant effects were observed in reducing perioperative anxiety or postoperative pain in this population. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/0167482X.2025.2519385
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 1
    Subjects:
      – SubjectFull: Music therapy
        Type: general
      – SubjectFull: Anxiety treatment
        Type: general
      – SubjectFull: Females
        Type: general
      – SubjectFull: Pain management
        Type: general
      – SubjectFull: Endometriosis
        Type: general
      – SubjectFull: Patients
        Type: general
      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Surgery
        Type: general
    Titles:
      – TitleFull: The effects of music therapy on pain and anxiety in young nulliparous patients undergoing laparoscopic cystectomy for endometriosis: a randomized controlled trial.
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          Name:
            NameFull: Li, Wenwei
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            NameFull: Feng, Huiyan
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            NameFull: Yang, Xiaohui
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            NameFull: Meng, Yue
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            NameFull: Yang, Yuebo
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            NameFull: Ye, Qingjian
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            – D: 01
              M: 12
              Text: Dec2025
              Type: published
              Y: 2025
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