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The effects of cognitive interventions on quality of life in infertile women: a meta-analysis of randomized controlled trials.

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Title: The effects of cognitive interventions on quality of life in infertile women: a meta-analysis of randomized controlled trials.
Authors: Yıldız Karaahmet, Aysu (AUTHOR), Bilgiç, Fatma Şule (AUTHOR), Yılmaz, Tülay (AUTHOR), Shafaati Laleh, Shahla (AUTHOR)
Source: Journal of Psychosomatic Obstetrics & Gynecology. Dec2025, Vol. 46 Issue 1, p1-16. 16p.
Subjects: Quality of life, Mental health, Cognitive therapy, Therapeutics, Randomized controlled trials, Female infertility, Reproductive health
Abstract: Infertility can lead to significant psychological distress, including depression and anxiety, adversely affecting the quality of life and treatment outcomes for affected women. This study systematically reviews non-pharmacological interventions, particularly cognitive behavioral therapy (CBT), aimed at improving quality of life, mental health, and birth rates among infertile women. A comprehensive literature search was conducted across multiple databases (PUBMED/MEDLINE, Embase, Scopus, Web of Science, and ULAKBİM) up to 22 February 2025, following PRISMA guidelines, with registration in the PROSPERO database (CRD42023457742). The analysis included randomized controlled trials (RCTs) focusing on CBT, with quality of life as the primary outcome. Eight studies involving 687 women met the inclusion criteria. Meta-analysis results revealed significant enhancements in quality of life (SMD: 1.97), alongside notable reductions in depression (SMD: −3.34) and anxiety (MD: −2.09). Additionally, a positive trend in pregnancy rates was observed (MD: 0.48). Despite the promising findings, the overall quality of evidence was deemed low to moderate due to potential biases. This meta-analysis underscores the effectiveness of CBT in improving mental health and quality of life in infertile women, highlighting the need for further high-quality research to validate these outcomes and endorse cognitive interventions in infertility treatment. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The effects of cognitive interventions on quality of life in infertile women: a meta-analysis of randomized controlled trials.
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  Data: <searchLink fieldCode="AR" term="%22Yıldız+Karaahmet%2C+Aysu%22">Yıldız Karaahmet, Aysu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bilgiç%2C+Fatma+Şule%22">Bilgiç, Fatma Şule</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yılmaz%2C+Tülay%22">Yılmaz, Tülay</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shafaati+Laleh%2C+Shahla%22">Shafaati Laleh, Shahla</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Psychosomatic+Obstetrics+%26+Gynecology%22">Journal of Psychosomatic Obstetrics & Gynecology</searchLink>. Dec2025, Vol. 46 Issue 1, p1-16. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Female+infertility%22">Female infertility</searchLink><br /><searchLink fieldCode="DE" term="%22Reproductive+health%22">Reproductive health</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Infertility can lead to significant psychological distress, including depression and anxiety, adversely affecting the quality of life and treatment outcomes for affected women. This study systematically reviews non-pharmacological interventions, particularly cognitive behavioral therapy (CBT), aimed at improving quality of life, mental health, and birth rates among infertile women. A comprehensive literature search was conducted across multiple databases (PUBMED/MEDLINE, Embase, Scopus, Web of Science, and ULAKBİM) up to 22 February 2025, following PRISMA guidelines, with registration in the PROSPERO database (CRD42023457742). The analysis included randomized controlled trials (RCTs) focusing on CBT, with quality of life as the primary outcome. Eight studies involving 687 women met the inclusion criteria. Meta-analysis results revealed significant enhancements in quality of life (SMD: 1.97), alongside notable reductions in depression (SMD: −3.34) and anxiety (MD: −2.09). Additionally, a positive trend in pregnancy rates was observed (MD: 0.48). Despite the promising findings, the overall quality of evidence was deemed low to moderate due to potential biases. This meta-analysis underscores the effectiveness of CBT in improving mental health and quality of life in infertile women, highlighting the need for further high-quality research to validate these outcomes and endorse cognitive interventions in infertility treatment. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Psychosomatic Obstetrics & Gynecology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=190350987
RecordInfo BibRecord:
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        Value: 10.1080/0167482X.2025.2560828
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      – Code: eng
        Text: English
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        PageCount: 16
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        Type: general
      – SubjectFull: Mental health
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      – SubjectFull: Cognitive therapy
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      – SubjectFull: Therapeutics
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      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Female infertility
        Type: general
      – SubjectFull: Reproductive health
        Type: general
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      – TitleFull: The effects of cognitive interventions on quality of life in infertile women: a meta-analysis of randomized controlled trials.
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            NameFull: Yıldız Karaahmet, Aysu
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            NameFull: Bilgiç, Fatma Şule
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            NameFull: Yılmaz, Tülay
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            NameFull: Shafaati Laleh, Shahla
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            – D: 01
              M: 12
              Text: Dec2025
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