Are cervical vestibular evoked myogenic potential (cVEMP) sensitive enough for the evaluation of patients with relapsing-remitting multiple sclerosis?
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| Title: | Are cervical vestibular evoked myogenic potential (cVEMP) sensitive enough for the evaluation of patients with relapsing-remitting multiple sclerosis? |
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| Authors: | Pavlidis, Pavlos (AUTHOR), Papagianopoulos, Sotirios (AUTHOR), Gouveris, Haralampos (AUTHOR), Tseriotis, Vasilis Spyridon (AUTHOR), Staufenberg, Anna-Rebekka (AUTHOR), Kazis, Dimitrios (AUTHOR) |
| Source: | Neurological Sciences. Jan2026, Vol. 47 Issue 1, p1-6. 6p. |
| Abstract: | Background: Multiple sclerosis (MS) is a long-term neurological condition that impacts the brain and spinal cord. The infratentorial area houses the cerebellum and brainstem. Vestibular evoked myogenic potentials (VEMPs) are myogenic responses with short latency. Cervical vestibular evoked myogenic potential (cVEMP) represents a reflection of the vestibulocolic reflex. Methods: A total of 32 consecutive patients participated in the study (males, n = 12; females, n = 20). Cervical VEMP (cVEMP) were examined for latencies, conduction block, and amplitude asymmetry ratio, and the VEMP score was determined. MRI was examined for brainstem lesions collectively and individually for lesions in the pons, midbrain, and medulla oblongata. Their findings were compared to those of 32 healthy individuals. Results: In the research, 5 RRMS patients (2.1%) exhibited no reaction in the cVEMP test for both the right and left ear (as explained in Tables 1 and 2). The average latencies for P1 and N1 in the left ears of RRMS patients were notably greater than those in the control group, yielding p-values of 0.001 and 0.002, respectively. Nevertheless, there was no notable difference in the P1-N1 interval or mean amplitude of the left ear when comparing patients and controls (p > 0.05). Conversely, the P1 and N1 latencies, as well as the average P1-N1 interval for the patients’ right ears, were notably greater than those of the control group, with p-values of 0.01, 0.001, and 0.004, respectively. Extended latencies for P1 and N1 were noted in 42 (65%) of the 64 RRMS ears and in 27 ears (42%), respectively. Conclusion: Vestibular evoked myogenic potential has a high sensitivity (70%) in MS patients, and VEMP could be recommended as a useful complementary neurophysiological method to evaluate the MS patients. [ABSTRACT FROM AUTHOR] |
| Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 190815253 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Are cervical vestibular evoked myogenic potential (cVEMP) sensitive enough for the evaluation of patients with relapsing-remitting multiple sclerosis? – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pavlidis%2C+Pavlos%22">Pavlidis, Pavlos</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Papagianopoulos%2C+Sotirios%22">Papagianopoulos, Sotirios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gouveris%2C+Haralampos%22">Gouveris, Haralampos</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tseriotis%2C+Vasilis+Spyridon%22">Tseriotis, Vasilis Spyridon</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Staufenberg%2C+Anna-Rebekka%22">Staufenberg, Anna-Rebekka</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kazis%2C+Dimitrios%22">Kazis, Dimitrios</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Jan2026, Vol. 47 Issue 1, p1-6. 6p. – Name: Abstract Label: Abstract Group: Ab Data: Background: Multiple sclerosis (MS) is a long-term neurological condition that impacts the brain and spinal cord. The infratentorial area houses the cerebellum and brainstem. Vestibular evoked myogenic potentials (VEMPs) are myogenic responses with short latency. Cervical vestibular evoked myogenic potential (cVEMP) represents a reflection of the vestibulocolic reflex. Methods: A total of 32 consecutive patients participated in the study (males, n = 12; females, n = 20). Cervical VEMP (cVEMP) were examined for latencies, conduction block, and amplitude asymmetry ratio, and the VEMP score was determined. MRI was examined for brainstem lesions collectively and individually for lesions in the pons, midbrain, and medulla oblongata. Their findings were compared to those of 32 healthy individuals. Results: In the research, 5 RRMS patients (2.1%) exhibited no reaction in the cVEMP test for both the right and left ear (as explained in Tables 1 and 2). The average latencies for P1 and N1 in the left ears of RRMS patients were notably greater than those in the control group, yielding p-values of 0.001 and 0.002, respectively. Nevertheless, there was no notable difference in the P1-N1 interval or mean amplitude of the left ear when comparing patients and controls (p > 0.05). Conversely, the P1 and N1 latencies, as well as the average P1-N1 interval for the patients’ right ears, were notably greater than those of the control group, with p-values of 0.01, 0.001, and 0.004, respectively. Extended latencies for P1 and N1 were noted in 42 (65%) of the 64 RRMS ears and in 27 ears (42%), respectively. Conclusion: Vestibular evoked myogenic potential has a high sensitivity (70%) in MS patients, and VEMP could be recommended as a useful complementary neurophysiological method to evaluate the MS patients. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10072-025-08765-9 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 1 Titles: – TitleFull: Are cervical vestibular evoked myogenic potential (cVEMP) sensitive enough for the evaluation of patients with relapsing-remitting multiple sclerosis? Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pavlidis, Pavlos – PersonEntity: Name: NameFull: Papagianopoulos, Sotirios – PersonEntity: Name: NameFull: Gouveris, Haralampos – PersonEntity: Name: NameFull: Tseriotis, Vasilis Spyridon – PersonEntity: Name: NameFull: Staufenberg, Anna-Rebekka – PersonEntity: Name: NameFull: Kazis, Dimitrios IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 15901874 Numbering: – Type: volume Value: 47 – Type: issue Value: 1 Titles: – TitleFull: Neurological Sciences Type: main |
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