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Evaluation of the Relationship Between Network Centrality and Individual Sociodemographics and Behaviors Among People Who Inject Drugs.

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Title: Evaluation of the Relationship Between Network Centrality and Individual Sociodemographics and Behaviors Among People Who Inject Drugs.
Authors: Skov, Benjamin (AUTHOR), Buchanan, Ashley L. (AUTHOR), Katenka, Natallia V. (AUTHOR), Hoque Nadia, Tasmin (AUTHOR), Friedman, Samuel R. (AUTHOR), Nikolopoulos, Georgios K. (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 3, p357-365. 9p.
Subjects: HIV infection epidemiology, Altruism, Cross-sectional method, Intravenous drug abuse, Receiver operating characteristic curves, Research funding, Risk-taking behavior, Human sexuality, Unemployment, Multiple regression analysis, Scientific observation, Residential patterns, Multivariate analysis, Descriptive statistics, Sex customs, Odds ratio, Social networks, Social skills, Condoms, Sociodemographic factors, Housing, Confidence intervals, Interpersonal relations, Data analysis software, Intravenous drug abusers, Psychosocial factors
Geographic Terms: Greece
Abstract: Purpose: Understanding the types of individuals and their position in the network may improve interventions for people who inject drugs (PWID). Methods: From the Transmission Reduction Intervention Project (TRIP), which enrolled PWID and their contacts in Athens, Greece, from 2013 to 2015, we extracted the largest connected component of the network (i.e., the largest group of connected individuals) and identified members who were in the top quartile of the distribution for three network centrality measures: closeness, betweenness, and eigenvector. Using logistic regression, we evaluated associations between high centrality measures and individual sociodemographic characteristics and behaviors. We also varied the definition for high centrality. Results: Among 231 individuals, 80% were male and between the ages of 25-40 years. Over half of the individuals injected at least once per day, compared to less than daily. Individuals who injected at least once per day were more likely to have high closeness (odds ratio (OR) = 3.36; 95% confidence interval (CI) = 1.57, 8.42), high betweenness (OR = 2.22; 95% CI = 1.06, 4.67), and eigenvector centrality (OR = 4.50; 95% CI = 1.89,10.68). Individuals who engaged in sex without a condom were less likely to have high closeness (OR = 0.18; 95% CI = 0.07, 0.45) or eigenvector (OR = 0.19; 95% CI = 0.07, 0.49) centrality. Conclusions: Individual characteristics and behaviors were associated with centrality and may impact an individual's position in the network. These associations could be useful in identifying important community members to engage as part of public health initiatives. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Evaluation of the Relationship Between Network Centrality and Individual Sociodemographics and Behaviors Among People Who Inject Drugs.
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 3, p357-365. 9p.
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  Label: Abstract
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  Data: Purpose: Understanding the types of individuals and their position in the network may improve interventions for people who inject drugs (PWID). Methods: From the Transmission Reduction Intervention Project (TRIP), which enrolled PWID and their contacts in Athens, Greece, from 2013 to 2015, we extracted the largest connected component of the network (i.e., the largest group of connected individuals) and identified members who were in the top quartile of the distribution for three network centrality measures: closeness, betweenness, and eigenvector. Using logistic regression, we evaluated associations between high centrality measures and individual sociodemographic characteristics and behaviors. We also varied the definition for high centrality. Results: Among 231 individuals, 80% were male and between the ages of 25-40 years. Over half of the individuals injected at least once per day, compared to less than daily. Individuals who injected at least once per day were more likely to have high closeness (odds ratio (OR) = 3.36; 95% confidence interval (CI) = 1.57, 8.42), high betweenness (OR = 2.22; 95% CI = 1.06, 4.67), and eigenvector centrality (OR = 4.50; 95% CI = 1.89,10.68). Individuals who engaged in sex without a condom were less likely to have high closeness (OR = 0.18; 95% CI = 0.07, 0.45) or eigenvector (OR = 0.19; 95% CI = 0.07, 0.49) centrality. Conclusions: Individual characteristics and behaviors were associated with centrality and may impact an individual's position in the network. These associations could be useful in identifying important community members to engage as part of public health initiatives. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10826084.2025.2561244
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      – Code: eng
        Text: English
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      – SubjectFull: HIV infection epidemiology
        Type: general
      – SubjectFull: Altruism
        Type: general
      – SubjectFull: Cross-sectional method
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      – SubjectFull: Intravenous drug abuse
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      – SubjectFull: Receiver operating characteristic curves
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      – SubjectFull: Research funding
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      – SubjectFull: Risk-taking behavior
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      – SubjectFull: Human sexuality
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      – SubjectFull: Unemployment
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      – SubjectFull: Multiple regression analysis
        Type: general
      – SubjectFull: Scientific observation
        Type: general
      – SubjectFull: Residential patterns
        Type: general
      – SubjectFull: Multivariate analysis
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Sex customs
        Type: general
      – SubjectFull: Odds ratio
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      – SubjectFull: Condoms
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      – SubjectFull: Greece
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      – TitleFull: Evaluation of the Relationship Between Network Centrality and Individual Sociodemographics and Behaviors Among People Who Inject Drugs.
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