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Overview and Research Trends on Cluster Headache Disease: A Bibliometric and Natural Language Processing Approach.

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Title: Overview and Research Trends on Cluster Headache Disease: A Bibliometric and Natural Language Processing Approach.
Authors: Hoseinnezhad, Mohsen (AUTHOR), Khazaneha, Mahdiyeh (AUTHOR), Arvan, Hamide (AUTHOR), Togha, Mansoureh (AUTHOR), Chauhan, Anjali (AUTHOR)
Source: Acta Neurologica Scandinavica. 2/6/2026, Vol. 2026, p1-14. 14p.
Subjects: Cluster headache, Bibliometrics, Natural language processing, Pathological physiology, University research, Genetics, Medical protocols, Brain imaging
Abstract: Background: This study presents a comprehensive analysis of the trends and challenges in cluster headache research from 1936 to 2022, highlighting the increasing study trend and the significant contributions from the United States, Italy, and England. The study identifies the most important journals, productive authors, and centers in the field, shedding light on the defects and challenges in pathophysiology, genetics, diagnosis, treatment, and study methods of cluster headaches. Methods: Utilizing a bibliometric approach, the study examines the thematic and conceptual structural map, identifying key areas of focus in the pathophysiology, genetics, and neuroimaging studies of cluster headaches. The study also delves into the treatment phases and guidelines for cluster headaches, emphasizing the need for evidence‐based and physiopathology‐based treatment approaches. Results: The findings highlight the genetic and neuroimaging research gaps, the role of the hypothalamus, and the morphological alterations in the brain associated with cluster headaches. The study also discusses the limitations and challenges in the research and treatment of cluster headaches, emphasizing the need for improved clinical trial methodologies and treatment efficacy. Conclusion: The study concludes by underscoring the critical need for further research to address the limitations and challenges in understanding the pathophysiology, improving treatment efficacy, and enhancing the quality of life for individuals with cluster headaches. The study recommends future research with a comprehensive perspective to address the complexities and insufficiencies in the current understanding and treatment of cluster headaches. [ABSTRACT FROM AUTHOR]
Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Overview and Research Trends on Cluster Headache Disease: A Bibliometric and Natural Language Processing Approach.
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  Data: <searchLink fieldCode="AR" term="%22Hoseinnezhad%2C+Mohsen%22">Hoseinnezhad, Mohsen</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Khazaneha%2C+Mahdiyeh%22">Khazaneha, Mahdiyeh</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Arvan%2C+Hamide%22">Arvan, Hamide</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Togha%2C+Mansoureh%22">Togha, Mansoureh</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chauhan%2C+Anjali%22">Chauhan, Anjali</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. 2/6/2026, Vol. 2026, p1-14. 14p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Cluster+headache%22">Cluster headache</searchLink><br /><searchLink fieldCode="DE" term="%22Bibliometrics%22">Bibliometrics</searchLink><br /><searchLink fieldCode="DE" term="%22Natural+language+processing%22">Natural language processing</searchLink><br /><searchLink fieldCode="DE" term="%22Pathological+physiology%22">Pathological physiology</searchLink><br /><searchLink fieldCode="DE" term="%22University+research%22">University research</searchLink><br /><searchLink fieldCode="DE" term="%22Genetics%22">Genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+protocols%22">Medical protocols</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+imaging%22">Brain imaging</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: This study presents a comprehensive analysis of the trends and challenges in cluster headache research from 1936 to 2022, highlighting the increasing study trend and the significant contributions from the United States, Italy, and England. The study identifies the most important journals, productive authors, and centers in the field, shedding light on the defects and challenges in pathophysiology, genetics, diagnosis, treatment, and study methods of cluster headaches. Methods: Utilizing a bibliometric approach, the study examines the thematic and conceptual structural map, identifying key areas of focus in the pathophysiology, genetics, and neuroimaging studies of cluster headaches. The study also delves into the treatment phases and guidelines for cluster headaches, emphasizing the need for evidence‐based and physiopathology‐based treatment approaches. Results: The findings highlight the genetic and neuroimaging research gaps, the role of the hypothalamus, and the morphological alterations in the brain associated with cluster headaches. The study also discusses the limitations and challenges in the research and treatment of cluster headaches, emphasizing the need for improved clinical trial methodologies and treatment efficacy. Conclusion: The study concludes by underscoring the critical need for further research to address the limitations and challenges in understanding the pathophysiology, improving treatment efficacy, and enhancing the quality of life for individuals with cluster headaches. The study recommends future research with a comprehensive perspective to address the complexities and insufficiencies in the current understanding and treatment of cluster headaches. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1155/ane/5110463
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        Text: English
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        Type: general
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      – SubjectFull: Natural language processing
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      – SubjectFull: Medical protocols
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      – TitleFull: Overview and Research Trends on Cluster Headache Disease: A Bibliometric and Natural Language Processing Approach.
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              Text: 2/6/2026
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              Y: 2026
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