Cognitively stimulating activities in multiple sclerosis: A qualitative feasibility study.

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Title: Cognitively stimulating activities in multiple sclerosis: A qualitative feasibility study.
Authors: Færk, Andreas Kirknæs (AUTHOR), Lund, Jakob Lindegaard (AUTHOR), Sellebjerg, Finn (AUTHOR), Chow, Helene Højsgaard (AUTHOR), Marstrand, Lisbet (AUTHOR), Loft, Mia (AUTHOR)
Source: Neuropsychological Rehabilitation. Mar2026, Vol. 36 Issue 2, p223-255. 33p.
Subjects: Multiple sclerosis, Feasibility studies, Qualitative research, Cognitive ability, Therapeutics, Randomized controlled trials, Recreation
Abstract: Introduction: Some people with multiple sclerosis (pwMS) exhibit high cognitive reserve (CR), potentially mitigating cognitive decline. Cognitively stimulating activities (CSAs) contribute to CR, suggesting that interventions entailing CSAs may enhance cognitive function in MS. Objectives/Aims: To evaluate the feasibility of an intervention designed to increase CSA participation (e.g., reading, writing, language learning). Methods: Participants were interviewed after a 12-week intervention in a randomized controlled trial. Participants were selected based on prespecified criteria to ensure sample diversity. Interviews were transcribed verbatim and analyzed using an inductive content analysis approach. Results: 14 participants were interviewed. The intervention was deemed feasible and acceptable by participants. Benefits included subjective cognitive improvements, increased impairment awareness, and engagement in compensatory strategies. Some reported indirect benefits, including improvements in mood and physical functioning. Barriers included a lack of training structure, technical aspects of the intervention, busy schedules, and guilt from not strictly adhering to protocol. Barriers were most prevalent in participants with progressive MS, younger age, busy schedules, and high pre-intervention activity levels. Conclusion: An individualized intervention to increase CSAs in pwMS is feasible. Future interventions could benefit from including people with low to medium participation in CSAs and should consider implementing measures of progress along the way to maintain motivation. [ABSTRACT FROM AUTHOR]
Copyright of Neuropsychological Rehabilitation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: Cognitively stimulating activities in multiple sclerosis: A qualitative feasibility study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Færk%2C+Andreas+Kirknæs%22">Færk, Andreas Kirknæs</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lund%2C+Jakob+Lindegaard%22">Lund, Jakob Lindegaard</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sellebjerg%2C+Finn%22">Sellebjerg, Finn</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chow%2C+Helene+Højsgaard%22">Chow, Helene Højsgaard</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marstrand%2C+Lisbet%22">Marstrand, Lisbet</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Loft%2C+Mia%22">Loft, Mia</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Neuropsychological+Rehabilitation%22">Neuropsychological Rehabilitation</searchLink>. Mar2026, Vol. 36 Issue 2, p223-255. 33p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Multiple+sclerosis%22">Multiple sclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Feasibility+studies%22">Feasibility studies</searchLink><br /><searchLink fieldCode="DE" term="%22Qualitative+research%22">Qualitative research</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+ability%22">Cognitive ability</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Recreation%22">Recreation</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Introduction: Some people with multiple sclerosis (pwMS) exhibit high cognitive reserve (CR), potentially mitigating cognitive decline. Cognitively stimulating activities (CSAs) contribute to CR, suggesting that interventions entailing CSAs may enhance cognitive function in MS. Objectives/Aims: To evaluate the feasibility of an intervention designed to increase CSA participation (e.g., reading, writing, language learning). Methods: Participants were interviewed after a 12-week intervention in a randomized controlled trial. Participants were selected based on prespecified criteria to ensure sample diversity. Interviews were transcribed verbatim and analyzed using an inductive content analysis approach. Results: 14 participants were interviewed. The intervention was deemed feasible and acceptable by participants. Benefits included subjective cognitive improvements, increased impairment awareness, and engagement in compensatory strategies. Some reported indirect benefits, including improvements in mood and physical functioning. Barriers included a lack of training structure, technical aspects of the intervention, busy schedules, and guilt from not strictly adhering to protocol. Barriers were most prevalent in participants with progressive MS, younger age, busy schedules, and high pre-intervention activity levels. Conclusion: An individualized intervention to increase CSAs in pwMS is feasible. Future interventions could benefit from including people with low to medium participation in CSAs and should consider implementing measures of progress along the way to maintain motivation. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Neuropsychological Rehabilitation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/09602011.2025.2501641
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      – Code: eng
        Text: English
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        PageCount: 33
        StartPage: 223
    Subjects:
      – SubjectFull: Multiple sclerosis
        Type: general
      – SubjectFull: Feasibility studies
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      – SubjectFull: Qualitative research
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      – SubjectFull: Cognitive ability
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      – SubjectFull: Therapeutics
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      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Recreation
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      – TitleFull: Cognitively stimulating activities in multiple sclerosis: A qualitative feasibility study.
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            NameFull: Færk, Andreas Kirknæs
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              M: 03
              Text: Mar2026
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              Y: 2026
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