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Antenatal and postpartum depression in women who conceived after infertility treatment: a longitudinal study.

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Title: Antenatal and postpartum depression in women who conceived after infertility treatment: a longitudinal study.
Authors: Ito, Yuka (AUTHOR), Nishi, Daisuke (AUTHOR)
Source: Journal of Reproductive & Infant Psychology. Mar2026, Vol. 44 Issue 2, p522-534. 13p.
Subjects: Infertility treatment, Risk assessment, Edinburgh Postnatal Depression Scale, Mobile apps, Statistical models, Repeated measures design, Research funding, Questionnaires, Puerperium, Postpartum depression, Multivariate analysis, Descriptive statistics, Prenatal care, Diseases, Surveys, Longitudinal method, Log-rank test, Survival analysis (Biometry), Confidence intervals, Data analysis software, Mental depression, Childbirth, Time, Patient aftercare, Proportional hazards models, Regression analysis, Pregnancy
Geographic Terms: Japan
Abstract: Background: Although the association between a history of infertility treatment and perinatal depression has been investigated, most research has been cross-sectional and has not used diagnostic assessment tools. Aims: This study investigates longitudinally the association between a history of infertility treatment and perinatal depression using WHO-Composite International Diagnostic Interview 3.0 (WHO-CIDI 3.0) and the Edinburgh Postnatal Depression Scale (EPDS). Methods: This study used data (N = 2,435) from the control group of a randomised controlled trial on a sample of pregnant women. Survival analysis was used to examine the influence of infertility treatment on perinatal depressive disorder evaluated by WHO-CIDI 3.0. The EPDS scores at four time points (T1 [baseline]: 18 ± 2 weeks gestation, T2: 32 weeks gestation, T3: 1 week postpartum, T4: 3 months postpartum) were analysed using generalised mixed model analysis. Results: The risk of experiencing a major depressive episode evaluated by WHO-CIDI 3.0 did not significantly differ between women conceiving through infertility treatment and those conceiving spontaneously (adjusted hazard ratio = 1.64, p = 0.109). The longitudinal analysis demonstrated that EPDS scores significantly increased at T3 and T4 among women conceiving through infertility treatment compared with those conceiving spontaneously (adjusted estimates of fixed effect from T1 to T3: 1.17, p < 0.01; from T1 to T4: 0.71, p = 0.022). Conclusion: Women conceiving through infertility treatment were not found to have a higher risk of diagnosable perinatal depressive disorder than those conceiving naturally. However, a history of infertility treatment can marginally increase sub-clinical postpartum depressive symptoms. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Reproductive & Infant Psychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Antenatal and postpartum depression in women who conceived after infertility treatment: a longitudinal study.
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– Name: Abstract
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  Data: Background: Although the association between a history of infertility treatment and perinatal depression has been investigated, most research has been cross-sectional and has not used diagnostic assessment tools. Aims: This study investigates longitudinally the association between a history of infertility treatment and perinatal depression using WHO-Composite International Diagnostic Interview 3.0 (WHO-CIDI 3.0) and the Edinburgh Postnatal Depression Scale (EPDS). Methods: This study used data (N = 2,435) from the control group of a randomised controlled trial on a sample of pregnant women. Survival analysis was used to examine the influence of infertility treatment on perinatal depressive disorder evaluated by WHO-CIDI 3.0. The EPDS scores at four time points (T1 [baseline]: 18 &#177; 2 weeks gestation, T2: 32 weeks gestation, T3: 1 week postpartum, T4: 3 months postpartum) were analysed using generalised mixed model analysis. Results: The risk of experiencing a major depressive episode evaluated by WHO-CIDI 3.0 did not significantly differ between women conceiving through infertility treatment and those conceiving spontaneously (adjusted hazard ratio = 1.64, p = 0.109). The longitudinal analysis demonstrated that EPDS scores significantly increased at T3 and T4 among women conceiving through infertility treatment compared with those conceiving spontaneously (adjusted estimates of fixed effect from T1 to T3: 1.17, p &lt; 0.01; from T1 to T4: 0.71, p = 0.022). Conclusion: Women conceiving through infertility treatment were not found to have a higher risk of diagnosable perinatal depressive disorder than those conceiving naturally. However, a history of infertility treatment can marginally increase sub-clinical postpartum depressive symptoms. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Journal of Reproductive &amp; Infant Psychology is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=191615623
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/02646838.2024.2380416
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 522
    Subjects:
      – SubjectFull: Infertility treatment
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Edinburgh Postnatal Depression Scale
        Type: general
      – SubjectFull: Mobile apps
        Type: general
      – SubjectFull: Statistical models
        Type: general
      – SubjectFull: Repeated measures design
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Puerperium
        Type: general
      – SubjectFull: Postpartum depression
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Prenatal care
        Type: general
      – SubjectFull: Diseases
        Type: general
      – SubjectFull: Surveys
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Log-rank test
        Type: general
      – SubjectFull: Survival analysis (Biometry)
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Childbirth
        Type: general
      – SubjectFull: Time
        Type: general
      – SubjectFull: Patient aftercare
        Type: general
      – SubjectFull: Proportional hazards models
        Type: general
      – SubjectFull: Regression analysis
        Type: general
      – SubjectFull: Pregnancy
        Type: general
      – SubjectFull: Japan
        Type: general
    Titles:
      – TitleFull: Antenatal and postpartum depression in women who conceived after infertility treatment: a longitudinal study.
        Type: main
  BibRelationships:
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      – PersonEntity:
          Name:
            NameFull: Ito, Yuka
      – PersonEntity:
          Name:
            NameFull: Nishi, Daisuke
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2026
              Type: published
              Y: 2026
          Identifiers:
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              Value: 44
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              Value: 2
          Titles:
            – TitleFull: Journal of Reproductive & Infant Psychology
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