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Management of schizophrenia patients in acute setting – a multinational survey of prescription patterns in five European countries.

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Title: Management of schizophrenia patients in acute setting – a multinational survey of prescription patterns in five European countries.
Authors: Bioque, Miquel (AUTHOR), Amerio, Andrea (AUTHOR), Ustohal, Libor (AUTHOR), Urban-Kowalczyk, Małgorzata (AUTHOR), Petrikis, Petros (AUTHOR), Alvarez-Barón, Elena (AUTHOR), Gabarda-Inat, Irene (AUTHOR)
Source: International Journal of Psychiatry in Clinical Practice. Mar2026, Vol. 30 Issue 1, p84-98. 15p.
Subjects: Schizophrenia treatment, World Wide Web, Patient compliance, Research funding, Questionnaires, Interviewing, Olanzapine, Schizophrenia, Antipsychotic agents, Treatment effectiveness, Risperidone, Surveys, Physician practice patterns, Research, Drug prescribing, Disease relapse, Drugs, Aripiprazole, Critical care medicine, Drug tolerance
Geographic Terms: Europe
Abstract: Objective: To analyse the use of antipsychotics for first-episode of psychosis (FEP) and relapsed schizophrenia, and the impact of predominant symptoms on decision making. Methods: A survey among 150 European psychiatrists was conducted using computer-assisted web interviewing to assess preferred medications, switching, dose adjustments, and maintenance therapy in acute FEP and relapse settings. Results: Negative or affective symptoms were reported as prevalent in 55% of FEP and 59% of relapsed schizophrenia cases, indicating significant unmet treatment needs. Olanzapine and risperidone were the most commonly prescribed antipsychotics for FEP, with treatment choices influenced by symptom profiles. Long-acting injectables (LAIs) were prescribed to 28% of FEP patients, with notable variation across countries (15–43%; p < 0.05). During hospitalisation, 41% of patients required therapy adjustments, while discharge decisions were driven by drug tolerability and symptom severity. For relapsed patients, non-adherence was identified as the primary cause of relapse (71%), and olanzapine, risperidone, and aripiprazole were the most prescribed treatments. Post-discharge adjustments for relapsed patients focused on adherence and long-term treatment goals. Conclusion: Despite the prevalence of negative or affective symptoms in FEP and relapsed patients, traditional antipsychotics remain the most prescribed treatments. Non-adherence and variability in LAI usage highlight the need for improved symptom-specific approaches and standardised LAI protocols. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Psychiatry in Clinical Practice is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Management of schizophrenia patients in acute setting – a multinational survey of prescription patterns in five European countries.
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  Data: Objective: To analyse the use of antipsychotics for first-episode of psychosis (FEP) and relapsed schizophrenia, and the impact of predominant symptoms on decision making. Methods: A survey among 150 European psychiatrists was conducted using computer-assisted web interviewing to assess preferred medications, switching, dose adjustments, and maintenance therapy in acute FEP and relapse settings. Results: Negative or affective symptoms were reported as prevalent in 55% of FEP and 59% of relapsed schizophrenia cases, indicating significant unmet treatment needs. Olanzapine and risperidone were the most commonly prescribed antipsychotics for FEP, with treatment choices influenced by symptom profiles. Long-acting injectables (LAIs) were prescribed to 28% of FEP patients, with notable variation across countries (15–43%; p &lt; 0.05). During hospitalisation, 41% of patients required therapy adjustments, while discharge decisions were driven by drug tolerability and symptom severity. For relapsed patients, non-adherence was identified as the primary cause of relapse (71%), and olanzapine, risperidone, and aripiprazole were the most prescribed treatments. Post-discharge adjustments for relapsed patients focused on adherence and long-term treatment goals. Conclusion: Despite the prevalence of negative or affective symptoms in FEP and relapsed patients, traditional antipsychotics remain the most prescribed treatments. Non-adherence and variability in LAI usage highlight the need for improved symptom-specific approaches and standardised LAI protocols. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of International Journal of Psychiatry in Clinical Practice is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=191985230
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/13651501.2025.2594101
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 15
        StartPage: 84
    Subjects:
      – SubjectFull: Schizophrenia treatment
        Type: general
      – SubjectFull: World Wide Web
        Type: general
      – SubjectFull: Patient compliance
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Interviewing
        Type: general
      – SubjectFull: Olanzapine
        Type: general
      – SubjectFull: Schizophrenia
        Type: general
      – SubjectFull: Antipsychotic agents
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Risperidone
        Type: general
      – SubjectFull: Surveys
        Type: general
      – SubjectFull: Physician practice patterns
        Type: general
      – SubjectFull: Research
        Type: general
      – SubjectFull: Drug prescribing
        Type: general
      – SubjectFull: Disease relapse
        Type: general
      – SubjectFull: Drugs
        Type: general
      – SubjectFull: Aripiprazole
        Type: general
      – SubjectFull: Critical care medicine
        Type: general
      – SubjectFull: Drug tolerance
        Type: general
      – SubjectFull: Europe
        Type: general
    Titles:
      – TitleFull: Management of schizophrenia patients in acute setting – a multinational survey of prescription patterns in five European countries.
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            NameFull: Ustohal, Libor
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            NameFull: Urban-Kowalczyk, Małgorzata
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            NameFull: Petrikis, Petros
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            – D: 01
              M: 03
              Text: Mar2026
              Type: published
              Y: 2026
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