View in EDS HTML Full Text PDF Full Text

Prevalence and Patterns of Cranial Nerve Involvement in CIDP, Autoimmune Nodopathy, MMN, and Anti‐MAG Neuropathy: A Multicenter Korea/UK Study of 582 Patients.

Saved in:
Bibliographic Details
Title: Prevalence and Patterns of Cranial Nerve Involvement in CIDP, Autoimmune Nodopathy, MMN, and Anti‐MAG Neuropathy: A Multicenter Korea/UK Study of 582 Patients.
Authors: Min, Young Gi (AUTHOR), Kim, Hyunjin (AUTHOR), Han, Hee Jo (AUTHOR), Yoon, Byeol‐A (AUTHOR), Kim, Jong Kuk (AUTHOR), Ju, Woohee (AUTHOR), Choi, Seok‐Jin (AUTHOR), Kim, Sung‐Min (AUTHOR), Kim, Ki Hoon (AUTHOR), Kwon, Young Nam (AUTHOR), Kim, Seung Woo (AUTHOR), Lee, Eun‐Jae (AUTHOR), Lim, Young‐Min (AUTHOR), Nazeer, Kabir K. (AUTHOR), Rajabally, Yusuf A. (AUTHOR), Shin, Ha Young (AUTHOR), Sung, Jung‐Joon (AUTHOR)
Source: European Journal of Neurology. Feb2026, Vol. 33 Issue 2, p1-8. 8p.
Subjects: Cranial nerves, Chronic inflammatory demyelinating polyradiculoneuropathy, Guillain-Barré syndrome, Optic nerve diseases, Facial paralysis, Trigeminal nerve diseases
Abstract: Background: Cranial nerve involvement is a well‐recognized feature in Guillain–Barré syndrome (GBS) but remains less well understood in chronic forms of autoimmune neuropathies. Earlier studies of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) were conducted before updated diagnostic criteria and the recognition of autoimmune nodopathy (AN), which may limit the interpretation of their findings. Methods: We retrospectively analyzed 582 patients with chronic autoimmune neuropathies—CIDP (n = 431), multifocal motor neuropathy (MMN) (n = 64), anti‐myelin‐associated glycoprotein (MAG) neuropathy (n = 54), and AN (n = 33)—from 4 Korean and 1 UK centers. Patients with cranial nerve involvement were identified and described. CIDP patients with cranial nerve involvement (cranial+ CIDP) were compared with those without (cranial− CIDP). Results: Cranial nerve involvement was observed in 8.8% (38/431) of CIDP and 24.2% (8/33) of AN patients but was absent in MMN (0/64) and anti‐MAG neuropathy (0/54). Facial palsy was overall the most common manifestation (CIDP: 45%, AN: 50%). Patients with AN more frequently exhibited bilateral optic neuropathy (50%) and facial diplegia (38%), while CIDP patients more often showed trigeminal neuropathy and oculomotor nerve palsy (both 32%). Compared with cranial− CIDP, cranial+ CIDP patients were more often younger, of variant subtypes (especially multifocal), presented (sub)acutely with preceding infection/vaccination, followed by relapsing–remitting rather than progressive courses, and achieved greater improvement despite greater pre‐treatment disability. Conclusions: Cranial nerve involvement serves as a diagnostic clue in chronic autoimmune neuropathies, particularly in identifying AN and CIDP. Cranial+ CIDP appears to represent a distinct subset with partial overlap to GBS, suggesting unique underlying mechanisms. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 192086914
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Prevalence and Patterns of Cranial Nerve Involvement in CIDP, Autoimmune Nodopathy, MMN, and Anti‐MAG Neuropathy: A Multicenter Korea/UK Study of 582 Patients.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Min%2C+Young+Gi%22">Min, Young Gi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Hyunjin%22">Kim, Hyunjin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Han%2C+Hee+Jo%22">Han, Hee Jo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yoon%2C+Byeol‐A%22">Yoon, Byeol‐A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Jong+Kuk%22">Kim, Jong Kuk</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ju%2C+Woohee%22">Ju, Woohee</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi%2C+Seok‐Jin%22">Choi, Seok‐Jin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Sung‐Min%22">Kim, Sung‐Min</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Ki+Hoon%22">Kim, Ki Hoon</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kwon%2C+Young+Nam%22">Kwon, Young Nam</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Seung+Woo%22">Kim, Seung Woo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee%2C+Eun‐Jae%22">Lee, Eun‐Jae</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lim%2C+Young‐Min%22">Lim, Young‐Min</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nazeer%2C+Kabir+K%2E%22">Nazeer, Kabir K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rajabally%2C+Yusuf+A%2E%22">Rajabally, Yusuf A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shin%2C+Ha+Young%22">Shin, Ha Young</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sung%2C+Jung‐Joon%22">Sung, Jung‐Joon</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Feb2026, Vol. 33 Issue 2, p1-8. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Cranial+nerves%22">Cranial nerves</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+inflammatory+demyelinating+polyradiculoneuropathy%22">Chronic inflammatory demyelinating polyradiculoneuropathy</searchLink><br /><searchLink fieldCode="DE" term="%22Guillain-Barré+syndrome%22">Guillain-Barré syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22Optic+nerve+diseases%22">Optic nerve diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Facial+paralysis%22">Facial paralysis</searchLink><br /><searchLink fieldCode="DE" term="%22Trigeminal+nerve+diseases%22">Trigeminal nerve diseases</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Cranial nerve involvement is a well‐recognized feature in Guillain–Barré syndrome (GBS) but remains less well understood in chronic forms of autoimmune neuropathies. Earlier studies of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) were conducted before updated diagnostic criteria and the recognition of autoimmune nodopathy (AN), which may limit the interpretation of their findings. Methods: We retrospectively analyzed 582 patients with chronic autoimmune neuropathies—CIDP (n = 431), multifocal motor neuropathy (MMN) (n = 64), anti‐myelin‐associated glycoprotein (MAG) neuropathy (n = 54), and AN (n = 33)—from 4 Korean and 1 UK centers. Patients with cranial nerve involvement were identified and described. CIDP patients with cranial nerve involvement (cranial+ CIDP) were compared with those without (cranial− CIDP). Results: Cranial nerve involvement was observed in 8.8% (38/431) of CIDP and 24.2% (8/33) of AN patients but was absent in MMN (0/64) and anti‐MAG neuropathy (0/54). Facial palsy was overall the most common manifestation (CIDP: 45%, AN: 50%). Patients with AN more frequently exhibited bilateral optic neuropathy (50%) and facial diplegia (38%), while CIDP patients more often showed trigeminal neuropathy and oculomotor nerve palsy (both 32%). Compared with cranial− CIDP, cranial+ CIDP patients were more often younger, of variant subtypes (especially multifocal), presented (sub)acutely with preceding infection/vaccination, followed by relapsing–remitting rather than progressive courses, and achieved greater improvement despite greater pre‐treatment disability. Conclusions: Cranial nerve involvement serves as a diagnostic clue in chronic autoimmune neuropathies, particularly in identifying AN and CIDP. Cranial+ CIDP appears to represent a distinct subset with partial overlap to GBS, suggesting unique underlying mechanisms. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=192086914
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/ene.70512
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1
    Subjects:
      – SubjectFull: Cranial nerves
        Type: general
      – SubjectFull: Chronic inflammatory demyelinating polyradiculoneuropathy
        Type: general
      – SubjectFull: Guillain-Barré syndrome
        Type: general
      – SubjectFull: Optic nerve diseases
        Type: general
      – SubjectFull: Facial paralysis
        Type: general
      – SubjectFull: Trigeminal nerve diseases
        Type: general
    Titles:
      – TitleFull: Prevalence and Patterns of Cranial Nerve Involvement in CIDP, Autoimmune Nodopathy, MMN, and Anti‐MAG Neuropathy: A Multicenter Korea/UK Study of 582 Patients.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Min, Young Gi
      – PersonEntity:
          Name:
            NameFull: Kim, Hyunjin
      – PersonEntity:
          Name:
            NameFull: Han, Hee Jo
      – PersonEntity:
          Name:
            NameFull: Yoon, Byeol‐A
      – PersonEntity:
          Name:
            NameFull: Kim, Jong Kuk
      – PersonEntity:
          Name:
            NameFull: Ju, Woohee
      – PersonEntity:
          Name:
            NameFull: Choi, Seok‐Jin
      – PersonEntity:
          Name:
            NameFull: Kim, Sung‐Min
      – PersonEntity:
          Name:
            NameFull: Kim, Ki Hoon
      – PersonEntity:
          Name:
            NameFull: Kwon, Young Nam
      – PersonEntity:
          Name:
            NameFull: Kim, Seung Woo
      – PersonEntity:
          Name:
            NameFull: Lee, Eun‐Jae
      – PersonEntity:
          Name:
            NameFull: Lim, Young‐Min
      – PersonEntity:
          Name:
            NameFull: Nazeer, Kabir K.
      – PersonEntity:
          Name:
            NameFull: Rajabally, Yusuf A.
      – PersonEntity:
          Name:
            NameFull: Shin, Ha Young
      – PersonEntity:
          Name:
            NameFull: Sung, Jung‐Joon
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 13515101
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: European Journal of Neurology
              Type: main
ResultId 1