Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications.
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| Title: | Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications. |
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| Authors: | Hajikarimloo, Bardia (AUTHOR), Mohammadzadeh, Ibrahim (AUTHOR), Habibi, Mohammad Amin (AUTHOR), Tos, Salem M. (AUTHOR), Yaseen, Haris (AUTHOR), Chisvo, Nathan (AUTHOR), Sabahi, Mohammadmahdi (AUTHOR), Alrashidi, Qais (AUTHOR), Adada, Badih (AUTHOR), Borghei-Razavi, Hamid (AUTHOR) |
| Source: | Neurological Sciences. Apr2026, Vol. 47 Issue 4, p1-13. 13p. |
| Abstract: | Background: Chiari malformation type I (CM-I) is a neurological disorder characterized by cerebellar tonsillar herniation and is often associated with syringomyelia. Posterior fossa decompression (PFD) is the primary treatment, although the optimal extent of decompression remains a topic of debate. Intraoperative ultrasonography (IOUS) offers real-time visualization to support informed surgical decision-making. This study aimed to assess the effectiveness and safety of IOUS-guided surgery in CM-I. Methods: This systematic review followed PRISMA guidelines and searched the literature up to July 5, 2025. Studies that utilized IOUS and reported related outcomes were included. A random-effects meta-analysis was employed to pool proportions, and a meta-regression analysis was conducted to explore heterogeneity. Results: Twenty-one non-randomized observational studies, including 1,576 patients, 54.4% of whom were female, were included. The pooled clinical improvement rate was 88% (95% CI: 81%–93%), and the syrinx improvement/resolution rate was 87% (95% CI: 77%–95%). The pooled reoperation rate was 6% (95% CI: 3%–9%), and the complication rate was 6% (95% CI: 3%–8%). Meta-regression revealed that longer disease duration, motor/sensory deficits, and duraplasty were associated with improved syrinx outcomes. Conclusion: IOUS-guided surgery in CM-I is linked to positive clinical and radiological improvements and low complication rates. IOUS can serve as a helpful tool for customizing decompression during CM-I surgery. Larger, prospective, multi-center studies are needed to confirm these findings. [ABSTRACT FROM AUTHOR] |
| Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 192236635 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hajikarimloo%2C+Bardia%22">Hajikarimloo, Bardia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mohammadzadeh%2C+Ibrahim%22">Mohammadzadeh, Ibrahim</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Habibi%2C+Mohammad+Amin%22">Habibi, Mohammad Amin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tos%2C+Salem+M%2E%22">Tos, Salem M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yaseen%2C+Haris%22">Yaseen, Haris</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chisvo%2C+Nathan%22">Chisvo, Nathan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sabahi%2C+Mohammadmahdi%22">Sabahi, Mohammadmahdi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alrashidi%2C+Qais%22">Alrashidi, Qais</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Adada%2C+Badih%22">Adada, Badih</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Borghei-Razavi%2C+Hamid%22">Borghei-Razavi, Hamid</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Apr2026, Vol. 47 Issue 4, p1-13. 13p. – Name: Abstract Label: Abstract Group: Ab Data: Background: Chiari malformation type I (CM-I) is a neurological disorder characterized by cerebellar tonsillar herniation and is often associated with syringomyelia. Posterior fossa decompression (PFD) is the primary treatment, although the optimal extent of decompression remains a topic of debate. Intraoperative ultrasonography (IOUS) offers real-time visualization to support informed surgical decision-making. This study aimed to assess the effectiveness and safety of IOUS-guided surgery in CM-I. Methods: This systematic review followed PRISMA guidelines and searched the literature up to July 5, 2025. Studies that utilized IOUS and reported related outcomes were included. A random-effects meta-analysis was employed to pool proportions, and a meta-regression analysis was conducted to explore heterogeneity. Results: Twenty-one non-randomized observational studies, including 1,576 patients, 54.4% of whom were female, were included. The pooled clinical improvement rate was 88% (95% CI: 81%–93%), and the syrinx improvement/resolution rate was 87% (95% CI: 77%–95%). The pooled reoperation rate was 6% (95% CI: 3%–9%), and the complication rate was 6% (95% CI: 3%–8%). Meta-regression revealed that longer disease duration, motor/sensory deficits, and duraplasty were associated with improved syrinx outcomes. Conclusion: IOUS-guided surgery in CM-I is linked to positive clinical and radiological improvements and low complication rates. IOUS can serve as a helpful tool for customizing decompression during CM-I surgery. Larger, prospective, multi-center studies are needed to confirm these findings. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10072-026-08879-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Titles: – TitleFull: Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hajikarimloo, Bardia – PersonEntity: Name: NameFull: Mohammadzadeh, Ibrahim – PersonEntity: Name: NameFull: Habibi, Mohammad Amin – PersonEntity: Name: NameFull: Tos, Salem M. – PersonEntity: Name: NameFull: Yaseen, Haris – PersonEntity: Name: NameFull: Chisvo, Nathan – PersonEntity: Name: NameFull: Sabahi, Mohammadmahdi – PersonEntity: Name: NameFull: Alrashidi, Qais – PersonEntity: Name: NameFull: Adada, Badih – PersonEntity: Name: NameFull: Borghei-Razavi, Hamid IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 15901874 Numbering: – Type: volume Value: 47 – Type: issue Value: 4 Titles: – TitleFull: Neurological Sciences Type: main |
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