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Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients.

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Title: Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients.
Authors: Luikku, Antti J. (AUTHOR), Matikka, Sara (AUTHOR), Heikkinen, Sami (AUTHOR), Lipponen, Anssi (AUTHOR), Luostarinen, Katja (AUTHOR), Koivisto, Timo (AUTHOR), Leinonen, Ville (AUTHOR), Huttunen, Jukka (AUTHOR), Jyrkkänen, Henna‐Kaisa (AUTHOR)
Source: Pain Practice. Apr2026, Vol. 26 Issue 4, p1-8. 8p.
Subjects: Trigeminal neuralgia treatment, Pain measurement, Repeated measures design, Patient safety, Logistic regression analysis, Sex distribution, Radio frequency therapy, Treatment effectiveness, Retrospective studies, Descriptive statistics, Treatment duration, Electrocoagulation (Medicine), Surgical complications, Odds ratio, Reoperation, Medical records, Acquisition of data, Catheter ablation, Data analysis software, Confidence intervals
Geographic Terms: Finland
Abstract: Background: Trigeminal neuralgia (TN) is a pain condition characterized by paroxysmal, electric shock‐like facial pain, affecting one or more areas of the branches. Approximately 33%–50% of patients require invasive treatment. Radiofrequency thermocoagulation (RFTC) is an established method for managing drug‐resistant and chronic TN. This study evaluates treatment response quality and complication rates in repeated RFTC procedures for TN patients. Methods: In this retrospective analysis, patient records were extracted from the electronic medical records of Kuopio University Hospital, using the trigeminal neuralgia diagnosis code and the procedure code for thermal destruction of a cranial nerve. Data collected included sex, age, treatment outcomes at 3‐month follow‐up, presence of complications, technical details, and procedural success for each intervention. Results: Data from 140 patients were analyzed. An excellent or good response was observed in 79% of patients after the first procedure, 62.9% after the second, and 42.3% after the third. Complication rates were 15.7%, 19.6%, and 42.9%, respectively. Logistic regression analysis showed that complication risk was significantly associated with tertiary procedure and female sex. Development of painful post‐traumatic trigeminal neuropathy (PTTN) was more common after repeated interventions; 1.4% after the first, 3.1% after the second, and 13.8% after the third procedure. Conclusions: RFTC is an effective and safe method for treatment for persistent trigeminal neuralgia when conservative treatment fails. However, its benefits diminish, and risks increase with each additional procedure, particularly the third. Based on these findings, reintervention should generally be limited to a single repeat procedure. [ABSTRACT FROM AUTHOR]
Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients.
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  Data: <searchLink fieldCode="AR" term="%22Luikku%2C+Antti+J%2E%22">Luikku, Antti J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Matikka%2C+Sara%22">Matikka, Sara</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heikkinen%2C+Sami%22">Heikkinen, Sami</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lipponen%2C+Anssi%22">Lipponen, Anssi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Luostarinen%2C+Katja%22">Luostarinen, Katja</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Koivisto%2C+Timo%22">Koivisto, Timo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leinonen%2C+Ville%22">Leinonen, Ville</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Huttunen%2C+Jukka%22">Huttunen, Jukka</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jyrkkänen%2C+Henna‐Kaisa%22">Jyrkkänen, Henna‐Kaisa</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="DE" term="%22Finland%22">Finland</searchLink>
– Name: Abstract
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  Data: Background: Trigeminal neuralgia (TN) is a pain condition characterized by paroxysmal, electric shock‐like facial pain, affecting one or more areas of the branches. Approximately 33%–50% of patients require invasive treatment. Radiofrequency thermocoagulation (RFTC) is an established method for managing drug‐resistant and chronic TN. This study evaluates treatment response quality and complication rates in repeated RFTC procedures for TN patients. Methods: In this retrospective analysis, patient records were extracted from the electronic medical records of Kuopio University Hospital, using the trigeminal neuralgia diagnosis code and the procedure code for thermal destruction of a cranial nerve. Data collected included sex, age, treatment outcomes at 3‐month follow‐up, presence of complications, technical details, and procedural success for each intervention. Results: Data from 140 patients were analyzed. An excellent or good response was observed in 79% of patients after the first procedure, 62.9% after the second, and 42.3% after the third. Complication rates were 15.7%, 19.6%, and 42.9%, respectively. Logistic regression analysis showed that complication risk was significantly associated with tertiary procedure and female sex. Development of painful post‐traumatic trigeminal neuropathy (PTTN) was more common after repeated interventions; 1.4% after the first, 3.1% after the second, and 13.8% after the third procedure. Conclusions: RFTC is an effective and safe method for treatment for persistent trigeminal neuralgia when conservative treatment fails. However, its benefits diminish, and risks increase with each additional procedure, particularly the third. Based on these findings, reintervention should generally be limited to a single repeat procedure. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=192816903
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        Value: 10.1111/papr.70148
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        Text: English
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        Type: general
      – SubjectFull: Pain measurement
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      – SubjectFull: Repeated measures design
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      – SubjectFull: Patient safety
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Retrospective studies
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      – SubjectFull: Finland
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      – TitleFull: Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients.
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              Text: Apr2026
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