Patterns and Determinants of Polystimulant Use Among Patients Seeking Treatment for Stimulant Use Disorders.

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Title: Patterns and Determinants of Polystimulant Use Among Patients Seeking Treatment for Stimulant Use Disorders.
Authors: Janssen, Eric (AUTHOR), Vuolo, Mike (AUTHOR), Véron, Sophie (AUTHOR), Spilka, Stanislas (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 7, p1064-1071. 8p.
Subjects: Substance abuse risk factors, Substance abuse, Cross-sectional method, Risk assessment, Statistical hypothesis testing, Intravenous drug abuse, Methamphetamine, Central nervous system stimulants, Substance abuse treatment, Questionnaires, Multiple regression analysis, Mental illness, Amphetamines, Descriptive statistics, Age distribution, Help-seeking behavior, Hallucinogenic drugs, Odds ratio, Research, Treatment programs, Data analysis software, Confidence intervals, Drug utilization, Educational attainment
Geographic Terms: France
Abstract: Objective: To estimate the prevalence and identify factors associated with polystimulant use (2 or more stimulants during the past 30 d), a specific case of polysubstance use, among patients seeking treatment for stimulant use disorder (StUD). Method: The data come from a national database of patients seeking treatment for StUD in France between 2012 and 2022 (n = 60211, 21.7% females). We conducted multilevel logistic regression to assess sociodemographic and psychiatric factors as well as concurrent use of psychoactive substances on polystimulant use. Results: Overall, the prevalence of polystimulant use was 12.5%. Descriptive findings suggested a slight increase over time; however, the result did not hold in the multivariable analysis. The odds of concurrent use were higher among patients aged 25–34 years, the more educated, who sought treatment for (meth)amphetamine disorders, who injected, with psychiatric disorders, and patients who used hallucinogens during the past 30 d. Polystimulant use was negatively associated with age at onset. No association with gender was detected. Conclusions: Our study suggests that polystimulant use varies by demographic factors and mostly occurs at later ages. Clinical strategies should target patients of younger age, with higher educational level, and should integrate mental health interventions as needed for those who were early initiators. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Patterns and Determinants of Polystimulant Use Among Patients Seeking Treatment for Stimulant Use Disorders.
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  Data: <searchLink fieldCode="AR" term="%22Janssen%2C+Eric%22">Janssen, Eric</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vuolo%2C+Mike%22">Vuolo, Mike</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Véron%2C+Sophie%22">Véron, Sophie</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Spilka%2C+Stanislas%22">Spilka, Stanislas</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 7, p1064-1071. 8p.
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  Data: <searchLink fieldCode="DE" term="%22France%22">France</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Objective: To estimate the prevalence and identify factors associated with polystimulant use (2 or more stimulants during the past 30 d), a specific case of polysubstance use, among patients seeking treatment for stimulant use disorder (StUD). Method: The data come from a national database of patients seeking treatment for StUD in France between 2012 and 2022 (n = 60211, 21.7% females). We conducted multilevel logistic regression to assess sociodemographic and psychiatric factors as well as concurrent use of psychoactive substances on polystimulant use. Results: Overall, the prevalence of polystimulant use was 12.5%. Descriptive findings suggested a slight increase over time; however, the result did not hold in the multivariable analysis. The odds of concurrent use were higher among patients aged 25–34 years, the more educated, who sought treatment for (meth)amphetamine disorders, who injected, with psychiatric disorders, and patients who used hallucinogens during the past 30 d. Polystimulant use was negatively associated with age at onset. No association with gender was detected. Conclusions: Our study suggests that polystimulant use varies by demographic factors and mostly occurs at later ages. Clinical strategies should target patients of younger age, with higher educational level, and should integrate mental health interventions as needed for those who were early initiators. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10826084.2025.2593572
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      – Code: eng
        Text: English
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        PageCount: 8
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      – SubjectFull: Cross-sectional method
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      – SubjectFull: Risk assessment
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      – SubjectFull: Statistical hypothesis testing
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      – SubjectFull: Intravenous drug abuse
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      – SubjectFull: Methamphetamine
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      – SubjectFull: Central nervous system stimulants
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      – SubjectFull: France
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      – TitleFull: Patterns and Determinants of Polystimulant Use Among Patients Seeking Treatment for Stimulant Use Disorders.
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              Text: 2026
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