Association of age, gender, and body mass index with gallstone disease: Evidence from a case–control study at a tertiary care institute.
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| Title: | Association of age, gender, and body mass index with gallstone disease: Evidence from a case–control study at a tertiary care institute. |
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| Authors: | Agarwal, Komal (AUTHOR), Kumar, Jitendra (AUTHOR), Goyal, Ritik (AUTHOR), Raina, Rajni (AUTHOR) |
| Source: | Saudi Journal for Health Sciences. Jan-Apr2026, Vol. 15 Issue 1, p46-51. 6p. |
| Subjects: | Sex factors in disease, Family history (Medicine), Disease risk factors, Gallstones, Body mass index, Aging, Case-control method, Tertiary care |
| Geographic Terms: | New Delhi (India) |
| Abstract: | Background: Gallstone disease (GSD) poses a major health burden worldwide, contributing significantly to morbidity. While various modifiable and nonmodifiable risk factors, including age, gender, and body mass index (BMI), have been commonly associated with GSD development, recent studies have reported inconsistent results. In addition, regional disparities in GSD prevalence and risk factors remain insufficiently explored. Aims: This study aims to evaluate the association of age, gender, and BMI with GSD among patients presenting to a high-volume tertiary care hospital in North Delhi. Settings and Design: A hospital-based case–control study was conducted among patients in the General Surgery Department of a Tertiary care hospital. Materials and Methods: The study included 91 ultrasound-confirmed cases of GSD, along with an equal number of age- and sex-matched controls without GSD. Data on demographics, lifestyle, medical history, and BMI were collected. Statistical analysis used Chi-square tests and conditional logistic regression, with significance set at P < 0.05. Results: Females comprised 85.7% of cases, with nearly one-third belonging to the younger age group. Although the mean BMI was higher among cases, differences in age and BMI between groups were not statistically significant in this matched cohort. A positive family history of GSD or gallbladder carcinoma showed a significant association. No significant associations were observed with lifestyle factors such as diet, alcohol use, smoking, or physical activity. Conclusion: Female gender and positive family history remain important risk factors for GSD, whereas no significant associations were found with age, BMI, or lifestyle habits in this cohort. The findings suggest a potential shift in traditional risk factor profiles, warranting further investigation. [ABSTRACT FROM AUTHOR] |
| Copyright of Saudi Journal for Health Sciences is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 193371654 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Association of age, gender, and body mass index with gallstone disease: Evidence from a case–control study at a tertiary care institute. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Agarwal%2C+Komal%22">Agarwal, Komal</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kumar%2C+Jitendra%22">Kumar, Jitendra</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Goyal%2C+Ritik%22">Goyal, Ritik</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Raina%2C+Rajni%22">Raina, Rajni</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Saudi+Journal+for+Health+Sciences%22">Saudi Journal for Health Sciences</searchLink>. Jan-Apr2026, Vol. 15 Issue 1, p46-51. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Sex+factors+in+disease%22">Sex factors in disease</searchLink><br /><searchLink fieldCode="DE" term="%22Family+history+%28Medicine%29%22">Family history (Medicine)</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Gallstones%22">Gallstones</searchLink><br /><searchLink fieldCode="DE" term="%22Body+mass+index%22">Body mass index</searchLink><br /><searchLink fieldCode="DE" term="%22Aging%22">Aging</searchLink><br /><searchLink fieldCode="DE" term="%22Case-control+method%22">Case-control method</searchLink><br /><searchLink fieldCode="DE" term="%22Tertiary+care%22">Tertiary care</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22New+Delhi+%28India%29%22">New Delhi (India)</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Gallstone disease (GSD) poses a major health burden worldwide, contributing significantly to morbidity. While various modifiable and nonmodifiable risk factors, including age, gender, and body mass index (BMI), have been commonly associated with GSD development, recent studies have reported inconsistent results. In addition, regional disparities in GSD prevalence and risk factors remain insufficiently explored. Aims: This study aims to evaluate the association of age, gender, and BMI with GSD among patients presenting to a high-volume tertiary care hospital in North Delhi. Settings and Design: A hospital-based case–control study was conducted among patients in the General Surgery Department of a Tertiary care hospital. Materials and Methods: The study included 91 ultrasound-confirmed cases of GSD, along with an equal number of age- and sex-matched controls without GSD. Data on demographics, lifestyle, medical history, and BMI were collected. Statistical analysis used Chi-square tests and conditional logistic regression, with significance set at P < 0.05. Results: Females comprised 85.7% of cases, with nearly one-third belonging to the younger age group. Although the mean BMI was higher among cases, differences in age and BMI between groups were not statistically significant in this matched cohort. A positive family history of GSD or gallbladder carcinoma showed a significant association. No significant associations were observed with lifestyle factors such as diet, alcohol use, smoking, or physical activity. Conclusion: Female gender and positive family history remain important risk factors for GSD, whereas no significant associations were found with age, BMI, or lifestyle habits in this cohort. The findings suggest a potential shift in traditional risk factor profiles, warranting further investigation. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Saudi Journal for Health Sciences is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.4103/sjhs.sjhs_162_25 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 46 Subjects: – SubjectFull: Sex factors in disease Type: general – SubjectFull: Family history (Medicine) Type: general – SubjectFull: Disease risk factors Type: general – SubjectFull: Gallstones Type: general – SubjectFull: Body mass index Type: general – SubjectFull: Aging Type: general – SubjectFull: Case-control method Type: general – SubjectFull: Tertiary care Type: general – SubjectFull: New Delhi (India) Type: general Titles: – TitleFull: Association of age, gender, and body mass index with gallstone disease: Evidence from a case–control study at a tertiary care institute. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Agarwal, Komal – PersonEntity: Name: NameFull: Kumar, Jitendra – PersonEntity: Name: NameFull: Goyal, Ritik – PersonEntity: Name: NameFull: Raina, Rajni IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan-Apr2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 22781900 Numbering: – Type: volume Value: 15 – Type: issue Value: 1 Titles: – TitleFull: Saudi Journal for Health Sciences Type: main |
| ResultId | 1 |
