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Prescription Opioid Misuse Among Sexual and Gender Minority (SGM) Youth in the United States: A Nationally Representative Study.

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Title: Prescription Opioid Misuse Among Sexual and Gender Minority (SGM) Youth in the United States: A Nationally Representative Study.
Authors: Kreider, Sophia L. (AUTHOR), Harrison, Lauren (AUTHOR), Reece-Nguyen, Travis (AUTHOR), Groenewald, Cornelius B. (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 8, p1250-1257. 8p.
Subjects: Substance abuse, Cross-sectional method, Sexual orientation, Pearson correlation (Statistics), Gender identity, Risk-taking behavior, High school students, Chi-squared test, Multivariate analysis, Descriptive statistics, Teenagers' conduct of life, Opioid analgesics, Sexual minorities, Drugs, Health equity, Data analysis software, Adolescence
Geographic Terms: United States
Abstract: Purpose: Recent research supports that sexual and gender minority (SGM) youth are at increased risk of prescription opioid misuse. Yet, the national prevalence of prescription opioid misuse in this population remains poorly described. Methods: Cross-sectional analysis of the 2023 Youth Risk and Behavior Survey (YRBS). Over 20,100 youth in grades 9–12 reported on their sexual and gender identities as well as current (past 30 days) and lifetime prescription opioid misuse. Weighted, multivariate Poisson regression analyses examined associations between SGM identities and current and lifetime opioid misuse controlling for demographic factors, other substance use behaviors, and depressive symptoms. Results: Prevalence of current and lifetime prescription opioid misuse was significantly higher among SGM youth compared to their non-SGM peers (7.0% vs. 3.7% for current misuse [p < 0.0001]; 17.8% vs. 9.7% for lifetime misuse [p < 0.0001]). Multivariate Poisson regression analyses support these findings for lifetime opioid misuse (aPR: 1.3; 95% CI: 1.1–1.6; p = 0.006) after controlling for covariates, but do not for current opioid misuse (aPR: 1.3; 95% CI: 0.9–1.8; p = 0.119). Across SGM identities, being gay or lesbian, bisexual, transgender, or questioning one's gender identity/sexuality was associated with higher prevalence rates of lifetime opioid misuse. Only participants questioning their sexuality or gender identity had significantly higher prevalence rates for current opioid misuse. Discussion: These findings suggest that SGM youth have disproportionately higher prevalence rates of prescription opioid misuse nationally, necessitating targeted public health interventions to address these disparities. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Prescription Opioid Misuse Among Sexual and Gender Minority (SGM) Youth in the United States: A Nationally Representative Study.
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– Name: Abstract
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  Data: Purpose: Recent research supports that sexual and gender minority (SGM) youth are at increased risk of prescription opioid misuse. Yet, the national prevalence of prescription opioid misuse in this population remains poorly described. Methods: Cross-sectional analysis of the 2023 Youth Risk and Behavior Survey (YRBS). Over 20,100 youth in grades 9–12 reported on their sexual and gender identities as well as current (past 30 days) and lifetime prescription opioid misuse. Weighted, multivariate Poisson regression analyses examined associations between SGM identities and current and lifetime opioid misuse controlling for demographic factors, other substance use behaviors, and depressive symptoms. Results: Prevalence of current and lifetime prescription opioid misuse was significantly higher among SGM youth compared to their non-SGM peers (7.0% vs. 3.7% for current misuse [p &lt; 0.0001]; 17.8% vs. 9.7% for lifetime misuse [p &lt; 0.0001]). Multivariate Poisson regression analyses support these findings for lifetime opioid misuse (aPR: 1.3; 95% CI: 1.1–1.6; p = 0.006) after controlling for covariates, but do not for current opioid misuse (aPR: 1.3; 95% CI: 0.9–1.8; p = 0.119). Across SGM identities, being gay or lesbian, bisexual, transgender, or questioning one&#39;s gender identity/sexuality was associated with higher prevalence rates of lifetime opioid misuse. Only participants questioning their sexuality or gender identity had significantly higher prevalence rates for current opioid misuse. Discussion: These findings suggest that SGM youth have disproportionately higher prevalence rates of prescription opioid misuse nationally, necessitating targeted public health interventions to address these disparities. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Substance Use &amp; Misuse is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=193623164
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/10826084.2025.2601834
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1250
    Subjects:
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Sexual orientation
        Type: general
      – SubjectFull: Pearson correlation (Statistics)
        Type: general
      – SubjectFull: Gender identity
        Type: general
      – SubjectFull: Risk-taking behavior
        Type: general
      – SubjectFull: High school students
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Teenagers' conduct of life
        Type: general
      – SubjectFull: Opioid analgesics
        Type: general
      – SubjectFull: Sexual minorities
        Type: general
      – SubjectFull: Drugs
        Type: general
      – SubjectFull: Health equity
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Adolescence
        Type: general
      – SubjectFull: United States
        Type: general
    Titles:
      – TitleFull: Prescription Opioid Misuse Among Sexual and Gender Minority (SGM) Youth in the United States: A Nationally Representative Study.
        Type: main
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            NameFull: Kreider, Sophia L.
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            NameFull: Harrison, Lauren
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            NameFull: Reece-Nguyen, Travis
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            NameFull: Groenewald, Cornelius B.
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            – D: 01
              M: 07
              Text: 2026
              Type: published
              Y: 2026
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