Clinical Differences Between Inpatients With and Without Alexithymia in Substance Use Disorder Treatment.

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Title: Clinical Differences Between Inpatients With and Without Alexithymia in Substance Use Disorder Treatment.
Authors: Remacle, Florine (AUTHOR), Kempeneers, Philippe (AUTHOR), Mreyen, Kristina (AUTHOR), Pallincourt, Romain (AUTHOR), Simon, Jessica (AUTHOR), Wildemeersch, Géraldine (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 8, p1268-1276. 9p.
Subjects: Substance abuse treatment, Emotion regulation, Self-esteem testing, Statistical power analysis, Repeated measures design, Self-efficacy, Center for Epidemiologic Studies Depression Scale, Research funding, Alexithymia, Hospital care, Questionnaires, Hospital patients, Severity of illness index, Anxiety, Emotions, Rumination (Cognition), Confidence, Desire, Motivation (Psychology), State-Trait Anxiety Inventory, Psychological stress, Analysis of variance, Belgians, Psychiatric hospitals, Psychological tests, Mental depression, Self-perception
Abstract: Background: This study investigates the clinical evolution of Belgian individuals following an inpatient treatment for substance use disorder (SUD), based on the presence or absence of alexithymia, as defined by difficulties in emotional identification and expression. Objectives: The objective of this study was to examine differences in clinical evolution during inpatient SUD treatment between individuals with high versus low levels of alexithymia. Among 119 inpatients, 92 were classified into two groups based on TAS-20 scores: a high-alexithymia group (n1 = 51, 42.86%, TAS-20 > 60) and a low-alexithymia group (n2 = 41, 34.45%, TAS-20 < 52). Clinical assessments were conducted at baseline, during the first week of hospitalization, and then at 2 weeks (n1 = 35, n2 = 29), and after 4 weeks of treatment (n1 = 24, n2 = 14). Results: At baseline, high alexithymia scores were associated with higher anxiety, emotional reactivity, and depressive symptoms. However, differences in addiction-related indicators, such as craving and self-efficacy, were less pronounced. All patients showed improvements in clinical symptoms during treatment, particularly in perceived stress and ruminations, but those with high alexithymia retained higher symptom severity. While both groups reported similar levels of craving, patients with alexithymia appeared to struggle more with emotional regulation. Conclusions: These findings suggest that alexithymia may negatively impact emotional regulation during SUD treatment and potentially affect long-term recovery. The results highlight the need for increased interventions that enhance emotional processing in individuals with alexithymia. Limitations include the small sample size and reliance on self-report measures, which may affect generalizability. Overall, this research enhances understanding of alexithymia's contribution to SUD treatment and supports the necessity for tailored therapeutic approaches, warranting further investigation into long-term effects and specific interventions for alexithymic traits. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Clinical Differences Between Inpatients With and Without Alexithymia in Substance Use Disorder Treatment.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: This study investigates the clinical evolution of Belgian individuals following an inpatient treatment for substance use disorder (SUD), based on the presence or absence of alexithymia, as defined by difficulties in emotional identification and expression. Objectives: The objective of this study was to examine differences in clinical evolution during inpatient SUD treatment between individuals with high versus low levels of alexithymia. Among 119 inpatients, 92 were classified into two groups based on TAS-20 scores: a high-alexithymia group (n1 = 51, 42.86%, TAS-20 &gt; 60) and a low-alexithymia group (n2 = 41, 34.45%, TAS-20 &lt; 52). Clinical assessments were conducted at baseline, during the first week of hospitalization, and then at 2 weeks (n1 = 35, n2 = 29), and after 4 weeks of treatment (n1 = 24, n2 = 14). Results: At baseline, high alexithymia scores were associated with higher anxiety, emotional reactivity, and depressive symptoms. However, differences in addiction-related indicators, such as craving and self-efficacy, were less pronounced. All patients showed improvements in clinical symptoms during treatment, particularly in perceived stress and ruminations, but those with high alexithymia retained higher symptom severity. While both groups reported similar levels of craving, patients with alexithymia appeared to struggle more with emotional regulation. Conclusions: These findings suggest that alexithymia may negatively impact emotional regulation during SUD treatment and potentially affect long-term recovery. The results highlight the need for increased interventions that enhance emotional processing in individuals with alexithymia. Limitations include the small sample size and reliance on self-report measures, which may affect generalizability. Overall, this research enhances understanding of alexithymia&#39;s contribution to SUD treatment and supports the necessity for tailored therapeutic approaches, warranting further investigation into long-term effects and specific interventions for alexithymic traits. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Substance Use &amp; Misuse is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1080/10826084.2025.2604210
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        Text: English
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        Type: general
      – SubjectFull: Emotion regulation
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      – SubjectFull: Self-esteem testing
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      – SubjectFull: Statistical power analysis
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      – SubjectFull: Self-efficacy
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      – SubjectFull: Center for Epidemiologic Studies Depression Scale
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      – SubjectFull: Research funding
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      – SubjectFull: Alexithymia
        Type: general
      – SubjectFull: Hospital care
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Hospital patients
        Type: general
      – SubjectFull: Severity of illness index
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      – SubjectFull: Psychological stress
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      – SubjectFull: Self-perception
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      – TitleFull: Clinical Differences Between Inpatients With and Without Alexithymia in Substance Use Disorder Treatment.
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              M: 07
              Text: 2026
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